Abstract: An endoscope treatment tool includes: a cylindrical cap attached to an outer side of a distal-end section of an endoscope and having first and second radial directions intersecting each other; a treatment tool supported at an outer side of the cap in the first radial direction to be movable in the longitudinal direction; and a linear flexible coupling member coupling the treatment tool with the cap such that the grasper reaches a position where the grasper protrudes from a distal end of the cap. A swing section of the coupling member couples the cap with the treatment tool to allow relative movement in the second radial direction, and, in response to pressed forward in the longitudinal direction by the treatment tool, swings about a swing axis extending in the second radial direction while generating a tensile force and bending the treatment tool inward in the first radial direction.

Abstract: The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.

Abstract: Provided is an endoscope holder capable of turning or swinging an endoscope inserted into a body with the endoscope fixed at a predetermined insertion position. An endoscope holder (1) includes a holder main body (3) having an insertion hole (2), gripping members (7a) and (7b) configured to pinch an endoscope E inserted into the insertion hole (2), first elastic members (12a) and (12b) configured to urge in a direction in which the gripping members (7a) and (7b) are separated from each other, a pressing member (13) configure to press the gripping member (7a) toward the gripping member (7b), a switching mechanism (17) configured to hold or release a pressing state, rollers (10) provided in gripping members (7a) and (7b), and a second elastic member (15) configured to swingably support the gripping member (7b).

Abstract: Provided is an endoscope holder capable of turning or swinging an endoscope inserted into a body with the endoscope fixed at a predetermined insertion position. An endoscope holder (1) includes a holder main body (3) having an insertion hole (2), gripping members (7a) and (7b) configured to pinch an endoscope E inserted into the insertion hole (2), first elastic members (12a) and (12b) configured to urge in a direction in which the gripping members (7a) and (7b) are separated from each other, a pressing member (13) configure to press the gripping member (7a) toward the gripping member (7b), a switching mechanism (17) configured to hold or release a pressing state, rollers (10) provided in gripping members (7a) and (7b), and a second elastic member (15) configured to swingably support the gripping member (7b).

Abstract: An endoscope treatment tool includes: a cap defining a longitudinal axis and a proximal-end opening for insertion of a distal end section of an endoscope to detachably attach the cap to the endoscope; a treatment tool extending longitudinally along an outside of the cap and having a distal end configured for tissue manipulation; and a coupling member extending between the cap and the treatment tool to movably couple the treatment tool to the cap, the coupling member having high flexibility.

Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.

Abstract: An endoscope treatment tool includes: a cylindrical cap attached to an outer side of a distal-end section of an endoscope and having first and second radial directions intersecting each other; a treatment tool supported at an outer side of the cap in the first radial direction to be movable in the longitudinal direction; and a linear flexible coupling member coupling the treatment tool with the cap such that the grasper reaches a position where the grasper protrudes from a distal end of the cap. A swing section of the coupling member couples the cap with the treatment tool to allow relative movement in the second radial direction, and, in response to pressed forward in the longitudinal direction by the treatment tool, swings about a swing axis extending in the second radial direction while generating a tensile force and bending the treatment tool inward in the first radial direction.

Abstract: The purpose of the present invention is to provide an injectable sol into a body, suited for delivery through a catheter, and usable for tissue perforation closure, ulcer protection, or vascular embolization. Provided are a sol for tissue perforation closure, a sol for ulcer protection, and a sol for vascular embolization, each containing from 0.6 mass % to 3 mass % of a collagen, water, from 200 mM to 330 mM sodium chloride, and a buffer and having a pH from 6.0 to 9.0.

Abstract: Object of the present invention is to provide a safe sol for submucosal local injection which gels and creates a mucosal elevation having a high retention rate of mucosal elevation height when locally injected into a digestive submucosa. Provided is a sol for submucosal local injection containing from 0.2 mass % to 1.2 mass % of a collagen, water, a buffer, and from 200 mM to 420 mM sodium chloride.

Abstract: Provided is an endoscope holder capable of turning or swinging an endoscope inserted into a body with the endoscope fixed at a predetermined insertion position. An endoscope holder (1) includes a holder main body (3) having an insertion hole (2), gripping members (7a) and (7b) configured to pinch an endoscope E inserted into the insertion hole (2), first elastic members (12a) and (12b) configured to urge in a direction in which the gripping members (7a) and (7b) are separated from each other, a pressing member (13) configure to press the gripping member (7a) toward the gripping member (7b), a switching mechanism (17) configured to hold or release a pressing state, rollers (10) provided in gripping members (7a) and (7b), and a second elastic member (15) configured to swingably support the gripping member (7b).

Abstract: Materials and methods for preventing gastrointestinal obstruction are provided. A peptide comprising between about 7 amino acids and about 32 amino acids in a solution may be introduced to a target site. The peptide may undergo self-organization under physiological conditions and/or in the presence of a cation.

Abstract: The present invention relates to a flex-knife that enables a technique such as tissue excision to be carried out more easily, and is provided with: a rod-shaped high frequency knife which is endoscopically inserted into a body cavity and is for performing cutting procedures; a wire, the high frequency knife connected to the front end thereof; a sheath consisting of an insulating material, into which the wire is inserted; a main body, the back end of the sheath being connected thereto; and a slider to which the back end of the wire is fixed and which is disposed to the main body to enable sliding in the axial direction; wherein the high frequency knife has a large diameter part at its distal end, the large diameter part having an outer diameter that is larger than the inner diameter of the sheath.

Abstract: Materials and methods for preventing gastrointestinal obstruction are provided. A peptide comprising between about 7 amino acids and about 32 amino acids in a solution may be introduced to a target site. The peptide may undergo self-organization under physiological conditions and/or in the presence of a cation.

Abstract: A high-frequency treatment instrument having a sheath; an elongated extension member; a narrow portion provided on an inner surface of the sheath; and a pressing member which allows the elongated extension member to advance and retract only in a part of the sheath. The elongated extension member is advanced to form a first treatment electrode extending along a central axial line of the sheath and the elongated extension member is further advanced to form a second treatment electrode which intersects with the central axial line of the sheath.

Abstract: The endoscope treatment tool 1 has a distal end member 3 which is installed in an endoscope. A connection member 4 is attached to the distal end member 3 in a freely rotatable manner. In the connection member 4, a portion which is supported by a cap 12 of the distal end member 3 is a second pivot shaft 15. A portion penetrating a supporting member 21 of a treatment portion 5 is a first pivot shaft 23. The first pivot shaft 23 is also a rotational axis of a pair of forceps members 22 provided in the treatment member 5. When the forceps members 22 are used, a coil sheath 6 is extended by an operation at the side of the proximal end. The connection member 4 rotates about the second pivot shaft 15, which is a fulcrum, and the treatment portion 5 moves forward beyond the cap 12. In accordance with the present invention, it is possible to resolve the difficulty of procedures by positioning the treatment portion in an appropriate location.

Abstract: An endoscopic instrument includes: a high-frequency knife for carrying out incisional intervention; a wire having a distal end connected to the high-frequency knife; an outer sheath for allowing the wire to pass therethrough; a main body having a proximal end of the sheath fixed thereto; a first slider, capable of freely sliding on the main body, having the wire fixed thereto; at least a stopper projecting radially outward relative to the wire; a first abutment member making contact with the stopper and regulating distal sliding movement of the wire; and a projection-length-adjusting member, provided in the outer sheath, for regulating proximal sliding movement of the wire by making contact with the stopper. This configuration allows the high-frequency knife to be maintained at different projection lengths based on the stopper making contact with the first abutment member and the stopper making contact with the projection-length-adjusting member.

Abstract: The present invention relates to a flex-knife that enables a technique such as tissue excision to be carried out more easily, and is provided with: a rod-shaped high frequency knife which is endoscopically inserted into a body cavity and is for performing cutting procedures; a wire, the high frequency knife connected to the front end thereof; a sheath consisting of an insulating material, into which the wire is inserted; a main body, the back end of the sheath being connected thereto; and a slider to which the back end of the wire is fixed and which is disposed to the main body to enable sliding in the axial direction; wherein the high frequency knife has a large diameter part at its distal end, the large diameter part having an outer diameter that is larger than the inner diameter of the sheath.

Abstract: An endoscopic instrument includes: a high-frequency knife for carrying out incisional intervention; a wire having a distal end connected to the high-frequency knife; an outer sheath for allowing the wire to pass therethrough; a main body having a proximal end of the sheath fixed thereto; a first slider, capable of freely sliding on the main body, having the wire fixed thereto; at least a stopper projecting radially outward relative to the wire; a first abutment member making contact with the stopper and regulating distal sliding movement of the wire; and a projection-length-adjusting member, provided in the outer sheath, for regulating proximal sliding movement of the wire by making contact with the stopper. This configuration allows the high-frequency knife to be maintained at different projection lengths based on the stopper making contact with the first abutment member and the stopper making contact with the projection-length-adjusting member.

Abstract: The endoscope treatment tool 1 has a distal end member 3 which is installed in an endoscope. A connection member 4 is attached to the distal end member 3 in a freely rotatable manner. In the connection member 4, a portion which is supported by a cap 12 of the distal end member 3 is a second pivot shaft 15. A portion penetrating a supporting member 21 of a treatment portion 5 is a first pivot shaft 23. The first pivot shaft 23 is also a rotational axis of a pair of forceps members 22 provided in the treatment member 5. When the forceps members 22 are used, a coil sheath 6 is extended by an operation at the side of the proximal end. The connection member 4 rotates about the second pivot shaft 15, which is a fulcrum, and the treatment portion 5 moves forward beyond the cap 12. In accordance with the present invention, it is possible to resolve the difficulty of procedures by positioning the treatment portion in an appropriate location.

Abstract: A high-frequency treatment instrument for performing a high-frequency treatment on a pathological lesion portion includes an elongated flexible sheath 2, a pair of arm portions 3A and 3B which is disposed in the sheath 2 so as to freely extend and retract, which is in a closed state in the sheath, and which is opened in a direction moving away from a center axial line of the sheath 2 when it protrudes from the distal end of the sheath 2, a linear treatment electrode which is connected to the distal end sides of the pair of arm portions and which is stretched between the arm portions when the pair of arm portions are opened, an operating wire (elongated extension member) which is disposed in the sheath 2 so as to freely extend and retract and the distal end of which is connected to the treatment electrode, and an operating portion, to which the proximal ends of the sheath and the operating wire are connected, and which operates the operating wire to extend and retract relative to the sheath 2.