Abstract: The present invention relates to an ion exchange fiber including: a core fiber; and an ion exchange layer that is disposed at a vicinity of the core fiber and includes a crosslinked polymer compound having an ion exchange group, in which, in a cross section perpendicular to a longitudinal direction of the ion exchange fiber, an area of the ion exchange layer occupies 50% or more and 90% or less of a total cross sectional area, and the ion exchange fiber has a swelling ratio of 50% or less.

Abstract: A hybrid vehicle includes a motor generator used for driving the vehicle, an engine used in combination with the motor generator, an accelerator sensor arranged in an instructing unit instructing increase and decrease in required drive torque, and a control device starting the engine when a required engine output value exceeds a start threshold. The controller decreases the start threshold according to at least increase in required drive torque, and preferably decreases the start threshold further according to decrease in vehicle speed sensed by a vehicle speed sensor.

Abstract: An electrode unit of a spot welding machine in which a recessed fitting portion having a circular shape in section is formed in a surface of a projecting portion of an electrode holder. A first groove is formed in an inner peripheral surface of the recessed fitting portion. A cooling water passage continuous to the recessed fitting portion is formed in the electrode holder. A columnar fitting portion is formed in a base end of the abutting portion of the electrode. A second groove is formed in an outer peripheral surface of the fitting portion. The fitting portion is inserted in the recessed fitting portion. An O ring is fitted in the first groove and the second groove. Then the electrode is attached to the projecting portion. A cooling water circulated in the cooling water passage cools down the electrode and the projecting portion.

Abstract: A method for examining Alzheimer's disease comprising (1) the measurement step of measuring an amount of lidocaine or a metabolite thereof in a cerebrospinal fluid derived from a lidocaine-administered test subject, and (2) the determination step of determining whether the test subject has Alzheimer's disease or not on the basis of the measured amount.

Abstract: Process for producing compound of Formula: wherein P2, P3 and R2 are the same as defined below, characterized by comprising reacting a compound represented by Formula (7): wherein P3 means a protecting group for hydroxy group; and Het means a 1-phenyl-1H-tetrazol-5-yl group, with a compound represented by Formula (8): wherein P2 means a protecting group for hydroxy group; and R2 means a phenyl group which may be substituted, in the presence of a base.

Abstract: A process for producing a compound represented by Formula (11): wherein P1, P7, P8, P9 and R1 are the same as defined herein, characterized by including reacting a compound represented by Formula (12): with a compound represented by Formula (13): in the presence of a catalyst.

Abstract: Process for producing compound of Formula: wherein P2, P3 and R2 are the same as defined below, characterized by comprising reacting a compound represented by Formula (7): wherein P3 means a protecting group for hydroxy group; and Het means a 1-phenyl-1H-tetrazol-5-yl group, with a compound represented by Formula (8): wherein P2 means a protecting group for hydroxy group; and R2 means a phenyl group which may be substituted, in the presence of a base.

Abstract: The present invention provides a novel bioactive substance having an antitumor activity and a process for producing it, and a medical use thereof. Namely, it provides a 12-membered ring macrolide compound represented by the following formula obtained from the incubation solution of Streptomyces sp. Mer. 11107 or a variant thereof, a pharmacologically acceptable salt thereof or a hydrate of them, and a process for producing it.

Abstract: A hybrid vehicle includes a motor generator used for driving the vehicle, an engine used in combination with the motor generator, an accelerator sensor arranged in an instructing unit instructing increase and decrease in required drive torque, and a control device starting the engine when a required engine output value exceeds a start threshold. The controller decreases the start threshold according to at least increase in required drive torque, and preferably decreases the start threshold further according to decrease in vehicle speed sensed by a vehicle speed sensor.

Abstract: [Problems to be Solved] To provide an effective process for total synthesis of pladienolide B and pladienolide D having excellent anti-tumor activity and to provide useful intermediates in the above-described process. [Measure for Solving the Problem] A process for producing a compound represented by Formula (11): wherein P1, P7, P8, P9 and R1 are the same as defined below, characterized by including reacting a compound represented by Formula (12): wherein P7 means a hydrogen atom or a protecting group for hydroxy group; R1 means a hydrogen atom or a hydroxy group, with a compound represented by Formula (13): wherein P1 means a hydrogen atom or a protecting group for hydroxy group; P8 means a hydrogen atom, an acetyl group or a protecting group for hydroxy group; P9 means a hydrogen atom or a protecting group for hydroxy group; or P8 and P9 may form together a group represented by a formula: wherein R5 means a phenyl group which may have a substituent, in the presence of a catalyst.

Abstract: The present invention provides a novel compound exhibiting an excellent suppressing effect to cell injury caused by radicals and neurotoxicity induced by excitatory nuerotransmitters such as glutamate. Specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them. Wherein Z represents a bivalent organic group and the like of from 2 to 3 carbon atom(s) which may have a substituent; and R3 represents a carboxyl group and the like.

Abstract: The present invention provides a novel bioactive substance having an antitumor activity and a process for producing it, and a medical use thereof. Namely, it provides a 12-membered ring macrolide compound represented by the following formula obtained from the incubation solution of Streptomyces sp. Mer. 11107 or a variant thereof, a pharmacologically acceptable salt thereof or a hydrate of them, and a process for producing it.

Abstract: The present invention provides a novel bioactive substance having an antitumor activity and a process for producing it, and a medical use thereof. Namely, it provides a 12-membered ring macrolide compound represented by the following formula obtained from the incubation solution of Streptomyces sp. Mer.

Abstract: The present invention provides a novel compound exhibiting an excellent suppressing effect to cell injury caused by radicals and neurotoxicity induced by excitatory nuerotransmitters such as glutamate. Specifically, it provides a compound represented by the following formula, a salt thereof or a hydrate of them.

Abstract: An apparatus includes a passage along which a recording medium with magnetic information recorded thereon can travel and an information read head disposed along the passage for reading the magnetic information. The apparatus also includes a first print head disposed on the first side of the passage and a second print head disposed on the second side of the passage. The first print head prints information on a first surface of the recording media based on data obtained by the information read head and the second print head prints information on a second surface of the recording media based on the data obtained by the information read head. Methods of processing a recording medium with magnetic information recorded thereon also are disclosed.

Abstract: An apparatus includes a passage along which a recording medium with magnetic information recorded thereon can travel and an information read head disposed along the passage for reading the magnetic information. The apparatus also includes a first print head disposed on the first side of the passage and a second print head disposed on the second side of the passage. The first print head prints information on a first surface of the recording media based on data obtained by the information read head and the second print head prints information on a second surface of the recording media based on the data obtained by the information read head. Methods of processing a recording medium with magnetic information recorded thereon also are disclosed.

Abstract: An apparatus includes a passage along which a recording medium with magnetic information recorded thereon can travel and an information read head disposed along the passage for reading the magnetic information. The apparatus also includes a first print head disposed on the first side of the passage and a second print head disposed on the second side of the passage. The first print head prints information on a first surface of the recording media based on data obtained by the information read head and the second print head prints information on a second surface of the recording media based on the data obtained by the information read head. Methods of processing a recording medium with magnetic information recorded thereon also are disclosed.

Abstract: A winding shaft, for use in a printer allows a wound recording paper to be easily removed therefrom. The winding shaft includes a shaft main body, a winding portion and a support-removing member. The winding portion, which sandwiches the shaft main body, winds the recording paper therearound. The shaft main body includes a pair of support-removing members, which respectively project from the shaft main body. The two support-removing members are respectively supported on the two side portions of the shaft main body in such a manner that they can be freely rotated about their respective support shafts. A tension-coiled spring is bridgingly disposed between the two support-removing members, so that the two support-removing members remain in standing positions when no external force is applied to them.

Abstract: A winding shaft, for use in a printer, which allows a wound recording paper to be easily removed therefrom. The winding shaft includes a shaft main body, a winding portion and a support-removing member. The winding portion, which sandwiches the shaft main body, winds the recording paper therearound. The shaft main body includes a pair of support-removing members, which respectively project from the shaft main body. The two support-removing members are respectively supported on the two side portions of the shaft main body in such a manner that they can be freely rotated about their respective support shafts. A tension-coiled spring is bridgingly disposed between the two support-removing members, so that the two support-removing members remain in standing positions when no external force is applied to them.

Abstract: A print head 6 is disposed next to a transportation path for transporting a cut-sheet form V. A guide frame 17 with a guide member 17a projecting into the transportation path away from the print head 6 is disposed on the cut-sheet form V insertion opening side of the print head 6. A platen unit 16 with a platen 33 is mounted to rotate freely, and a frame member 30 is disposed on the platen unit 16. When the platen unit 16 is closed, the guide member 17a of the guide frame 17 and the guide member 30b of the frame member 30 touch, thus forming an ejection path guiding the roll paper S away from the junction with the cut-sheet form V transportation path. When the platen unit 16 is opened, the guide member 17a of guide frame 17 and the guide member 30b of frame member 30 separate, thereby enabling cut-sheet form V insertion.