Patents by Inventor Naoki EGASHIRA

Naoki EGASHIRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-AMINOBUT-2-ENAMIDE DERIVATIVES AND SALTS THEREOF
    Publication number: 20230023023
    Abstract: The present invention provides an antitumor agent comprising a compound or a pharmaceutically acceptable salt thereof that covalently binds to GTP-bound KRASG12C as an active ingredient.
    Type: Application
    Filed: October 29, 2020
    Publication date: January 26, 2023
    Inventors: KAZUAKI SHIBATA, YUICHI KAWAI, HIROKI ASAKURA, TETSUYA SUGIMOTO, NAOKI EGASHIRA, TOMOHIRO YAMAMOTO, TATSUYA SUZUKI, YUKI KATAOKA, TAKESHI SAGARA, TOSHIHIRO SAKAMOTO, HITOMI KONDO, CHRISTOPHER CHARLES FREDERICK HAMLETT, PATRICK SCHÖPF, DAVID GEOFFREY TWIGG
  • 5H-pyrrolo[2,3-D]pyrimidin-6(7H)-one derivative
    Patent number: 10538528
    Abstract: The invention of the present application provides a compound represented by Formula (I) or a salt thereof, which exhibits an inhibitory activity against at least one kinase selected from the group consisting of Akt kinase, Rsk kinase, and S6K kinase and/or a cell proliferation inhibiting effect and is useful as a prophylactic and/or therapeutic agent for diseases associated with the above-mentioned kinases, particularly cancer.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: January 21, 2020
    Assignee: Taiho Pahrmaceutical Co., Ltd.
    Inventors: Tetsuya Sugimoto, Toshihiro Sakamoto, Fuyuki Yamamoto, Yu Kobayakawa, Naoki Egashira, Koji Ichikawa, Takumitsu Machida
  • NOVEL 5H-PYRROLO[2,3-D]PYRIMIDIN-6(7H)-ONE DERIVATIVE
    Publication number: 20190292190
    Abstract: The invention of the present application provides a compound represented by Formula (I) or a salt thereof, which exhibits an inhibitory activity against at least one kinase selected from the group consisting of Akt kinase, Rsk kinase, and S6K kinase and/or a cell proliferation inhibiting effect and is useful as a prophylactic and/or therapeutic agent for diseases associated with the above-mentioned kinases, particularly cancer.
    Type: Application
    Filed: May 19, 2017
    Publication date: September 26, 2019
    Applicant: Taiho Pharmaceutical Co., Ltd.
    Inventors: Tetsuya SUGIMOTO, Toshihiro SAKAMOTO, Fuyuki YAMAMOTO, Yu KOBAYAKAWA, Naoki EGASHIRA, Koji ICHIKAWA, Takumitsu MACHIDA