Abstract: A composite sintered material includes: a plurality of diamond grains having an average grain size of less than or equal to 10 ?m; a plurality of cubic boron nitride grains having an average grain size of less than or equal to 2 ?m; and a plurality of aluminum oxide grains having an average grain size of less than or equal to 0.5 ?m; and a remainder of a binder phase, wherein at least parts of adjacent diamond grains are bound to one another, the binder phase includes cobalt, in the composite sintered material, a content of the diamond grains is from 30 to 92 volume %, a content of the cubic boron nitride grains is from 3 to 40 volume %, a content of the aluminum oxide grains is from 2 to 15 volume %, and a content of the cobalt is from 3 to 30 volume %.

Abstract: An immune checkpoint suppressant containing as an active ingredient a mixture of (a) to (g), which are koji mold, yeast, and/or lactic acid bacterium fermentation products of: (a) barley, black soybean, red rice, black rice, adzuki bean, adlay, Japanese barnyard millet, foxtail millet, and/or proso millet; (b) mandarin orange, grape, apple, Vitis Coignetiae berry, peach, persimmon, papaya, Japanese pear, watermelon, Japanese apricot, fig, Chinese quince fruit, kabocha squash, kumquat, Yuzu, loquat fruit, apricot, jujube, chestnut, matatabi fruit, and/or Japanese plum; (c) purple sweet potato, Jerusalem artichoke, carrot, onion, sweet potato, taro, Japanese wild yarn, daikon, red turnip, great burdock, lotus root, yacon, lily bulb, arrowhead, ginger, garlic, and/or turmeric; (d) cabbage, perilla, Moms leaf, fish mint, Japanese mugwort, Sasa veitchii, and/or dandelion; (e) kelp, wakame, and/or mozuku; (f) black sesame, walnut, and/or ginkgo nut; and (g) maitake and/or shiitake mushroom.

Abstract: A quality-of-life improving agent, with a plant fermented product that is a mixture of substances (a) to (g): (a) a koji mold fermented product of one type or two or more types of beans/grains; (b) a yeast and/or lactic acid bacterium fermented product of one type or two or more types of fruits; (c) a yeast and/or lactic acid bacterium fermented product of one type or two or more types of root vegetables/tubers; (d) a yeast and/or lactic acid bacterium fermented product of one type or two or more types of flowers/leafy vegetables; (e) a yeast and/or lactic acid bacterium fermented product of one type or two or more types of seaweeds; (f) a yeast and/or lactic acid bacterium fermented product of one type or two or more types of seeds; and (g) a yeast and/or lactic acid bacterium fermented product of one type or two types of mushrooms.

Abstract: A press-through packaging material is disclosed including, in sequence, a substrate, an opaque underlayer laminated on at least a part of the surface of the substrate, and a printing layer that contains a colored metal pigment, and that is formed on at least a part of the surface of the opaque underlayer. The colored metal pigment includes a metal pigment, an amorphous silicon oxide film layer formed on the surface of the metal pigment, and metal particles supported on a part of or on the entire surface of the amorphous silicon oxide film layer, the opaque underlayer having a mass per unit area of 0.5 g/m2 or more and 3.0 g/m2 or less, and the printing layer having a mass per unit area of 1.0 g/m2 or more and 3.5 g/m2 or less.

Abstract: An immune checkpoint suppressant containing as an active ingredient a mixture of (a) to (g), which are koji mold, yeast, and/or lactic acid bacterium fermentation products of: (a) barley, black soybean, red rice, black rice, adzuki bean, adlay, Japanese barnyard millet, foxtail millet, and/or proso millet; (b) mandarin orange, grape, apple, Vitis coignetiae berry, peach, persimmon, papaya, Japanese pear, watermelon, Japanese apricot, fig, Chinese quince fruit, kabocha squash, kumquat, Yuzu, loquat fruit, apricot, jujube, chestnut, matatabi fruit, and/or Japanese plum; (c) purple sweet potato, Jerusalem artichoke, carrot, onion, sweet potato, taro, Japanese wild yarn, daikon, red turnip, great burdock, lotus root, yacon, lily bulb, arrowhead, ginger, garlic, and/or turmeric; (d) cabbage, perilla, Morus leaf, fish mint, Japanese mugwort, Sasa veitchii, and/or dandelion; (e) kelp, wakame, and/or mozuku; (f) black sesame, walnut, and/or ginkgo nut; and (g) maitake and/or shiitake mushroom.

Abstract: A prophylactic agent for spontaneous cancer may contain a plant fermentation product as a mixture of (a) to (g), fermentation products of: (a) barley, black soybean, red rice, black rice, adzuki bean, adlay, Japanese barnyard millet, foxtail millet, and/or proso millet; (b) mandarin orange, grape, apple, Vitis coignetiae berry, peach, persimmon, papaya, Japanese pear, watermelon, Japanese apricot, fig, Chinese quince fruit, kabocha squash, kumquat, Yuzu, loquat fruit, apricot, jujube, chestnut, matatabi fruit, and/or Japanese plum; (c) purple sweet potato, Jerusalem artichoke, carrot, onion, sweet potato, taro, Japanese wild yarn, daikon, red turnip, great burdock, lotus root, yacon, lily bulb, arrowhead, ginger, garlic, and/or turmeric; (d) cabbage, perilla, Moms leaf, fish mint, Japanese mugwort, Sasa veitchii, and/or dandelion; (e) kelp, wakame, and/or mozuku; (f) black sesame, walnut, and/or ginkgo nut; and (g) maitake and/or shiitake.

Abstract: An object of the present invention is to provide a senescence retarding agent that delays the onset of senescence symptoms and extends longevity, and is superior in safety.

Abstract: An object of the present invention is to provide a senescence retarding agent that delays the onset of senescence symptoms and extends longevity, and is superior in safety.

Abstract: A laminate and the like capable of improving the barcode reading accuracy with a configuration having a smaller number of layers is provided. Further, a laminate and the like capable of further improving the barcode reading accuracy and further reducing the size of a barcode portion even when applied to a conventional layer configuration is provided. The laminate includes a colored barcode print layer 5, a base material layer 1, and a bead-containing coating layer 7 having beads 7b dispersed in a resin 7a.

Abstract: A laminate and the like capable of improving the barcode reading accuracy with a configuration having a smaller number of layers is provided. Further, a laminate and the like capable of further improving the barcode reading accuracy and further reducing the size of a barcode portion even when applied to a conventional layer configuration is provided. The laminate includes a colored barcode print layer 5, a base material layer 1, and a bead-containing coating layer 7 having beads 7b dispersed in a resin 7a.

Abstract: An agent for alleviating, treating and preventing vascular failure and a vascular endothelial cell-protecting agent characterized by containing, as an effective ingredient, at least one active oxygen scavenger such as astaxanthin and tocotrienols; and a food, a drink and an animal feed having an effect of alleviating, treating and preventing vascular failure and an effect of protecting vascular endothelial cells characterized by containing, as the effective ingredient, at least one active oxygen scavenger such as astaxanthin and tocotrienols.

Abstract: [Object] In recent years, life style-related diseases, particularly circulatory system diseases caused by the tendency toward high caloric diet, the change in life style, lack of exercise, stress and so on increased and have became a serious social problem. These diseases are caused mainly by injures in blood vessels. To prevent injures in blood vessels, there has been required a vascular endothelial cell-protecting agent and a food having an effect of protecting vascular endothelial cells.

Abstract: Facsimile apparatus stores, in a memory, a telephone number for connecting to a server of an Internet facsimile transmission service company. The facsimile apparatus transmits facsimile signals via the Internet, a registration number of a user of the service company, a facsimile number of the destination, and a protocol for connecting to the service company. Connection to a server of the service company is established by pressing a button and further processing for connection with the Internet is executed. The server of the service company converts the image information of the facsimile signals as received from the facsimile apparatus into image data of its own format appropriate for Internet transfer, selects a second server which is located close to the destination based on the destination facsimile number, and transfers the data via the Internet. The second server reconverts the image data into a format conforming to the destination facsimile, connects to the destination facsimile, and transmits the data.

Abstract: A method of purifying a polypeptide having a physiological activity such as one having interferon activities from a culture mixture of a microorganism obtained by a recombinant DNA technique and capable of producing the polypeptide is disclosed. The method comprises subjecting the cultured cells to extraction and purification in the presence of a salt of zinc or copper and polyethyleneimine thereby inhibiting decomposition and denaturation of the polypeptide. The extracted polypeptide can be further purified by column chromatographies using a column containing an anion exchange resin, column containing a cation exchange resin and column containing a gel filtration resin.