Patents by Inventor Naoki Muto
Naoki Muto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6943659Abstract: A varistor includes a varistor element, a first layer which is porous on the varistor element, and a second layer on th first coating. The thickness t (mm) of the second layer is not smaller than 1.3/V. where V(ml/g) is the volume of pores of the first layer exposed to an outside of the first layer. This varistor includes the outer layers protected from being broken even when a non-ohmic interface in a voltage non-linear resistor is broken down with a voltage exceeding a rated level.Type: GrantFiled: June 24, 2003Date of Patent: September 13, 2005Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Tsutomu Kitsui, Minoru Ouchi, Naoki Muto
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Publication number: 20050088273Abstract: A varistor includes a varistor element, a first layer which is porous on the varistor element, and a second layer on the first coating. The thickness t (mm) of the second layer is not smaller than 1.3/V, where V(ml/g) is the volume of pores of the first layer exposed to an outside of the first layer. This varistor includes the outer layers protected from being broken even when a non-ohmic interface in a voltage non-linear resistor is broken down with a voltage exceeding a rated level.Type: ApplicationFiled: June 24, 2003Publication date: April 28, 2005Inventors: Tsutomu Kitsui, Minoru Ouchi, Naoki Muto
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Patent number: 5238816Abstract: A novel .omega.-carboxyalcohol oxidase catalyzes at least one of the following reactions:R--CH.sub.2 OH+O.sub.2 .fwdarw.R--CHO+H.sub.2 O.sub.2 a)R--CHO+O.sub.2 +H.sub.2 O.fwdarw.R--COOH+H.sub.2 O.sub.2 b)wherein R is alkyl, alkenyl, .omega.-carboxyalkyl or .omega.-carboxyalkenyl. The enzyme has substrate specificity on at least 12-hydroxydodecanoic acid, 1-dodecanol, 1-decanol, 1-octanol and 1-hexanol, and has no substrate specificity on methanol, ethanol or glycerol. The enzyme does not require the presence of NAD or NADP for its use. Also disclosed is a process for producing the enzyme, an assay method for substrates of the enzyme, and a process for producing carboxylic acid employing the enzyme.Type: GrantFiled: November 5, 1991Date of Patent: August 24, 1993Assignee: Asahi Kasei Kogyo Kabushiki KaishaInventors: Shigeyuki Imamura, Naoki Muto, Kenya Ishizawa
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Patent number: 5206148Abstract: A method for assaying aliphatic alcohol, aliphatic aldehyde or .omega.-carboxylic acid derivatives thereof, using a novel .omega.-carboxyalcohol oxidase which catalyzes at least one of the following reactions:a) R--CH.sub.2 OH+O.sub.2 .fwdarw.R--CHO+H.sub.2 O.sub.2b) R--CHO+O.sub.2 +H.sub.2 O.fwdarw.R--COOH+H.sub.2 O.sub.2wherein R is alkyl, alkenyl, .omega.-carboxyalkyl or .omega.-carboxyalkenyl. The enzyme has substrate specificity on at least 12-hydroxydodecanoic acid, 1-dodecanol, 1-decanol, 1-octanol and 1-hexanol, and has no substrate specificity on methanol, ethanol or glycerol. The enzyme does not require the presence of NAD or NADP for its use. Also disclosed is a process for producing the enzyme, an assay method for substrates of the enzyme, and a process for producing carboxylic acid employing the enzyme.Type: GrantFiled: November 5, 1991Date of Patent: April 27, 1993Assignee: Asahi Kasei Kogyo Kabushiki KaishaInventors: Shigeyuki Imamura, Naoki Muto, Kenya Ishizawa
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Patent number: 5171681Abstract: A novel .omega.-carboxyalcohol oxidase catalyzes at least one of the following reactions:a) R--CH.sub.2 OH+O.sub.2 .fwdarw.R--CHO+H.sub.2 O.sub.2b) R--CHO+O.sub.2 +H.sub.2 O.fwdarw.R--COOH+H.sub.2 O.sub.2wherein R is alkyl, alkenyl, .omega.-carboxyalkyl or .omega.- carboxyalkenyl. The enzyme has substrate specificity on at least 12-hydroxydodecanoic acid, 1-dodecanol, 1-decanol, 1-octanol and 1-hexanol, and has no substrate specificity on methanol, ethanol or glycerol. The enzyme does not require the presence of NAD or NADP for its use. Also disclosed is a process for producing the enzyme, an assay method for substrates of the enzyme, and a process for producing carboxylic acid employing the enzyme.Type: GrantFiled: August 21, 1990Date of Patent: December 15, 1992Assignee: Toyo Jozo Kabushiki KaishaInventors: Shigeyuki Imamura, Naoki Muto, Kenya Ishizawa
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Patent number: 5081023Abstract: A antibiotic L53-18A and a pharmaceutically acceptable salt thereof which are useful for treatment of bacterial inventions are obtained by culturing, for example, Saccharopolyspora sp. L53-18 (FERM BP 2231) in a medium and the antibiotic accumulated therein is collected.Type: GrantFiled: December 27, 1989Date of Patent: January 14, 1992Assignee: Toyo Yozo Company, Ltd.Inventors: Satoshi Yaginuma, Atsuki Morishita, Naoki Muto, Kenya Ishizawa, Mitsuo Hayashi, Tetsu Saito
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L-glutamic acid oxidase (H.sub.2 O.sub.2 -generating), its production and analytical method therefor
Patent number: 4605615Abstract: L-glutamic acid oxidase having the following biochemical properties:(a) substrate specificity: L-glutamic acid,(b) enzyme action: catalyzes a reaction which forms one mole of .alpha.-ketoglutaric acid, one mole of ammonia and one mole of hydrogen peroxide from one mole of L-glutamic acid, one mole of oxygen and one mole of water, as follows: ##STR1## This oxidase is produced by culturing microorganisms belonging to genus Streptomyces in a nutrient medium and isolating the thus-produced L-glutamic acid oxidase. Particular microorganisms of genus Streptomyces are sp. A7700 FERM P-6241 (NRRL No. 15267) and sp. 8063 FERM P-6242 (NRRL No. 15268). The oxidase can be used for detecting L-glutamic acid or L-glutamate, in an aqueous sample, because it catalyzes a reaction which forms one mole of .alpha.-ketoglutaric acid, one mole of ammonia and one mole of hydrogen peroxide from one mole of glutamic acid, one mole of oxygen and one mole of water.Type: GrantFiled: March 2, 1983Date of Patent: August 12, 1986Assignee: Toyo Jozo Kabushiki KaishaInventors: Hidehiko Ishikawa, Hideo Misaki, Naoki Muto -
Patent number: 4525458Abstract: The invention is to provide a method for the production of sphingomyelinase, by culturing in a medium a sphingomyelinase-producing strain belonging to genus Streptomyces and collecting the resulting sphingomyelinase from the cultured medium. The strain, Streptomyces sp. A 9107, newly separated from a soil, is found preferable for the method of the present invention, and has been deposited as NRRL 15100 and FERM-P 4978.Type: GrantFiled: September 1, 1982Date of Patent: June 25, 1985Assignee: Toyo Jozo Company, Ltd.Inventors: Shigeyuki Imamura, Hideo Misaki, Naoki Muto
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Patent number: 4482707Abstract: Antibiotic saccharocins of the formula ##STR1## wherein R is hydrogen (saccharocin) or hydroxyl (3'-oxysaccharocin) are produced by culturing a microorganism belonging to the genus Saccharopolyspora, for example Saccharopolyspora sp. AC 3440 FERM-P No. 6238, in a conventional nutrient medium, and separating the thus-produced saccharocins from the cultured medium. The noval saccharocins exhibit anti-bacterial activity against Gram negative bacteria.Type: GrantFiled: December 8, 1982Date of Patent: November 13, 1984Assignee: Toyo Jozo Kabushiki KaishaInventors: Hideo Sakakibara, Shuzo Satoi, Masashi Awata, Hitoshi Sagai, Mitsuo Hayashi, Naoki Muto, Masaki Takada
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Patent number: 4423218Abstract: Antibiotic neplanocin A of the formula ##STR1## is produced by culturing Ampullariella sp. A 11079 FERM-P No. 4494 in a nutrient medium and then separating the neplanocin A thus produced from the culture medium.Type: GrantFiled: November 3, 1980Date of Patent: December 27, 1983Assignee: Toyo Jozo Kabushiki KaishaInventors: Masaru Otani, Satoshi Yaginuma, Masatoshi Tsujino, Naoki Muto, Tetsu Saito, Tadashiro Fujii
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Patent number: 4349667Abstract: Aminoglycoside antibiotic G-367-2 believed to have the formula ##STR1## is produced by culturing Dactylosporangium thailandense G-367 FERM-P No. 4840 in a nutrient medium and separating the produced antibiotic therefrom. It has strong antibacterial effect against Gram negative bacteria.Type: GrantFiled: July 9, 1980Date of Patent: September 14, 1982Assignee: Toyo Jozo Kabushiki KaishaInventors: Tadashiro Fujii, Shuzo Satoi, Naoki Muto, Mitsuo Hayashi, Akira Kodama, Masaru Otani
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Patent number: 4347323Abstract: A novel glycerol kinase is produced from the microorganism Streptomyces canus FERM-P No. 4977 and is useful as a diagnostic reagent for assay of triglycerides and glycerol in body fluids such as serum.Type: GrantFiled: May 28, 1980Date of Patent: August 31, 1982Assignee: Toyo Jozo Kabushiki KaishaInventors: Shigeyuki Imamura, Tohru Matsumoto, Naoki Muto, Hideo Misaki
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Patent number: 4321376Abstract: Neplanocin-B and -F of the formula ##STR1## in which Y is oxygen or a valence bond, are produced by culturing Ampullariella sp. A 11079 FERM-P No. 4494 in a nutrient medium and then separating the neplanocin-B and -F thus produced from the culture medium.Type: GrantFiled: December 7, 1979Date of Patent: March 23, 1982Assignee: Toyo Jozo Kabushiki KaishaInventors: Masaru Otani, Satoshi Yaginuma, Masatoshi Tsujino, Naoki Muto, Tetsu Saito, Tadashiro Fujii
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Patent number: 4297486Abstract: Aminoglycoside antibiotic G-367-1 believed to have the formulae ##STR1## is produced by culturing Dactylosporangium thailandense G-367 FERM-P No. 4840 in a nutrient medium and separating the produced antibiotic therefrom. It has strong antibacterial effect against Gram negative bacteria.Type: GrantFiled: April 3, 1980Date of Patent: October 27, 1981Assignee: Toyo Jozo Kabushiki KaishaInventors: Tadashiro Fujii, Shuzo Satoi, Naoki Muto, Mitsuo Hayashi, Akira Kodama, Masaru Otani
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Patent number: 4291021Abstract: A novel microorganism species belonging to the genus Micromonospora, i.e. Micromonospora sp. A 11725 is found to be capable of producing novel macrolide antibiotics A 11725 I, A 11725 II and A 11725 III. Novel antibiotics A 11725 Ia and A 11725 IIa are also found to be derived by chemical modification of the antibiotics A 11725 I and A 11725 II, respectively. All of these antibiotics or salts thereof exhibit excellent antibacterial and anti-mycoplasmal activities against various microorganisms such as Staphylococcus or Mycoplasma, and therefore useful for various purposes including medicaments.Type: GrantFiled: May 10, 1979Date of Patent: September 22, 1981Assignee: Toyo Jozo Company, Ltd.Inventors: Masaru Otani, Shuzo Satoi, Naoki Muto, Tetsu Saito, Tadashiro Fujii, Seiji Katsumata, Mitsuo Hayashi, Masaru Ono
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Patent number: 4288429Abstract: A group of sulfur-containing antibiotics, planothiocin-A, -B, -C, -D, -E, -F and -G, are produced by culturing Actinoplanes sp. A12526 in a nutrient medium, and separating the thus-produced planothiocins therefrom. The novel antibiotics have utility in therapeutic or prophylactic antibacterial compositions or feed additives for livestock, poultry or fish.Type: GrantFiled: August 5, 1980Date of Patent: September 8, 1981Assignee: Toyo Jozo Kabushiki KaishaInventors: Tadashiro Fujii, Satoshi Yaginuma, Naoki Muto, Mitsuo Hayashi
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Patent number: 4254256Abstract: An amino sugar compound represented by the general formula: ##STR1## (wherein m is an integer of 0 to 8, n is an integer of 1 to 8 and m+n is an integer of 1 to 8) has strong glycosidase inhibiting action and is produced by culturing an amino sugar compound producing microorganisms belonging to Streptomyces.Type: GrantFiled: December 12, 1978Date of Patent: March 3, 1981Assignee: Toyo Jozo company, Ltd.Inventors: Masaru Otani, Tetsu Saito, Shuzo Satoi, Junzo Mizoguchi, Naoki Muto
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Patent number: 4135980Abstract: A novel enzyme choline oxidase is produced by culturing a microorganism belonging to the genus Arthrobacter, and particularly the species Arthrobacter globiformis B-0577 FERM-P No. 3518, NRRL B-11097, and isolating the choline oxidase thus produced from the culture medium. Choline oxidase is useful for the determination of choline or betaine aldehyde in a sample by mixing the new product with the sample and then measuring the generated hydrogen peroxide, betaine or consumed oxygen.Type: GrantFiled: April 22, 1977Date of Patent: January 23, 1979Assignee: Toyo Jozo Kabushiki KaishaInventors: Shigeru Ikuta, Yoshifumi Horiuchi, Hideo Misaki, Kazuo Matsuura, Shigeyuki Imamura, Naoki Muto