Patents by Inventor Naoki SOGA

Naoki SOGA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10974246
    Abstract: A high-density micro-chamber array has a translucent flat substrate, a hydrophobic layer in which a plurality of micro-chambers are provided, and a lipid bilayer membrane formed in each of the openings of the micro-chambers, wherein an electrode is provided in each of the micro-chambers, and when the side of the substrate on which the hydrophobic layer is provided is directed upward, the micro-chamber array is configured such that with at least one of the following A) and B) being met, light entering the substrate from below is transmitted through the substrate and penetrates into the micro-chambers' interiors, and light entering the substrate from the micro-chambers' interiors is transmitted through the substrate and escapes toward below the substrate. A) The electrode is provided on an inner side surface of each of the micro-chambers. B) The electrode is transparent and provided on a bottom surface of each of the micro-chambers.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: April 13, 2021
    Assignee: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Rikiya Watanabe, Hiroyuki Noji, Naoki Soga
  • Publication number: 20200261877
    Abstract: A method for forming a lipid membrane vesicle includes: filling a chamber with a first aqueous solution by introducing it to a liquid flow path facing a microreactor chip hydrophobic layer main surface; forming a first lipid monolayer membrane in an opening part of the chamber filled with the solution; forming a second lipid monolayer membrane on a layer interface of the organic solvent formed on the main surface of the hydrophobic layer with a second aqueous solution by introducing the solution to the liquid flow path; allowing a first aqueous solution form in the chamber to alter to a spherical droplet covered with the first lipid monolayer membrane; and forming a lipid membrane vesicle by moving the droplet to a position of the second lipid monolayer membrane by applying a physical action, and by zipping the first lipid monolayer membrane covering the droplet and the second lipid monolayer membrane.
    Type: Application
    Filed: April 19, 2018
    Publication date: August 20, 2020
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Rikiya WATANABE, Naoki SOGA, Hiroyuki NOJI
  • Publication number: 20200038860
    Abstract: A microreactor chip includes a substrate and a hydrophobic layer that is a layer provided on the substrate and made of a hydrophobic substance and is formed so that openings of a plurality of chambers are arranged regularly on a main surface of the layer. Each chamber is provided with a first lipid bilayer membrane and a second lipid bilayer membrane that are disposed with a gap therebetween in a depth direction so as to fractionate the chamber in the depth direction.
    Type: Application
    Filed: March 2, 2018
    Publication date: February 6, 2020
    Applicant: THE UNIVERSITY OF TOKYO
    Inventors: Rikiya WATANABE, Hiroyuki NOJI, Naoki SOGA
  • Publication number: 20180104686
    Abstract: A high-density micro-chamber array has a translucent flat substrate, a hydrophobic layer in which a plurality of micro-chambers are provided, and a lipid bilayer membrane formed in each of the openings of the micro-chambers, wherein an electrode is provided in each of the micro-chambers, and when the side of the substrate on which the hydrophobic layer is provided is directed upward, the micro-chamber array is configured such that with at least one of the following A) and B) being met, light entering the substrate from below is transmitted through the substrate and penetrates into the micro-chambers' interiors, and light entering the substrate from the micro-chambers' interiors is transmitted through the substrate and escapes toward below the substrate. A) The electrode is provided on an inner side surface of each of the micro-chambers. B) The electrode is transparent and provided on a bottom surface of each of the micro-chambers.
    Type: Application
    Filed: June 7, 2016
    Publication date: April 19, 2018
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Rikiya WATANABE, Hiroyuki NOJI, Naoki SOGA