Abstract: Provided is a drug that allows highly-efficient skipping of exon. The present invention provides an antisense oligomer wherein two or more unit oligomers targeting sequences that are neither consecutive nor overlap with each other in the same exon are connected.

Abstract: A supported metal catalyst, including: a support that is a collective body of conductive particles; and dispersed active metal particles supported on the conductive particles. The conductive particles include a plurality of pores; an average entrance pore diameter of the pores is 1 to 20 nm; a standard deviation of the average entrance pore diameter is equal to or less than 50% of the average entrance pore diameter; a number fraction of the active metal particles supported in a surface layer region of the conductive particles divided by a total number of the active metal particles is equal to or more than 50%; the surface layer region is a region on a surface of the conductive particles or a region in the pores within a depth of 15 nm from the surface; and an average interparticle distance of the active metal particles is 5 to 20 nm.

Abstract: A method for purifying a gas inside a polymer film production furnace with the use of the purification catalyst is provided. A purification catalyst for a gas inside a polymer film production furnace, contains a mixed oxide composed of a manganese-based oxide containing manganese and potassium and having a cryptomelane structure, and copper oxide. A method for purifying a gas inside a polymer film production furnace, includes a step 1 of bringing hot air containing volatile and/or sublimable organic substances, generated during production of a polymer film by the polymer film production furnace, into contact with the catalyst provided inside or outside the furnace, at a temperature in the range of 200 to 350° C. to decompose the organic substances oxidatively, and a step 2 of refluxing all or a part of a resultant decomposition gas to the polymer film production furnace.

Abstract: A method for purifying a gas inside a polymer film production furnace with the use of the purification catalyst is provided. A purification catalyst for a gas inside a polymer film production furnace, contains a mixed oxide composed of a manganese-based oxide containing manganese and potassium and having a cryptomelane structure, and copper oxide. A method for purifying a gas inside a polymer film production furnace, includes a step 1 of bringing hot air containing volatile and/or sublimable organic substances, generated during production of a polymer film by the polymer film production furnace, into contact with the catalyst provided inside or outside the furnace, at a temperature in the range of 200 to 350° C. to decompose the organic substances oxidatively, and a step 2 of refluxing all or a part of a resultant decomposition gas to the polymer film production furnace.

Abstract: A high durability catalyst for decomposing volatile organic compounds (VOCs) or sublimable organic substances, generated inside a polymer film production furnace, at a high conversion rate is provided. A method for purifying a gas inside a polymer film production furnace with the use of the catalyst is also provided. Provided are a purification catalyst for a gas inside a polymer film production furnace, which contains a mixed oxide composed of a manganese-based oxide containing manganese and potassium and having a cryptomelane structure, and copper oxide; and a method for purifying a gas inside a polymer film production furnace, comprising a step 1 of bringing hot air containing volatile and/or sublimable organic substances, generated during production of a polymer film by the polymer film production furnace, into contact with the catalyst provided inside or outside the furnace, at a temperature in the range of 200 to 350° C.