Patents by Inventor Naoki Tsuno

Naoki Tsuno has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220098186
    Abstract: Provided herein are novel crystalline forms of a crystalline compound of Formula (I), which modulates the ORL-1 receptor. The crystalline compounds of Formula (I), compositions thereof, and methods of using thereof that are described herein are particularly useful for treatment, prevention, and management of several sleep disorders.
    Type: Application
    Filed: January 30, 2020
    Publication date: March 31, 2022
    Applicant: Purdue Pharma L.P.
    Inventors: Ronnie ORTIZ, David IGO, Naoki TSUNO, Mayu FUKUDA, Naoki MIYAKE
  • Patent number: 11111246
    Abstract: The invention relates to Substituted-Quinoxaline-Type Bridged-Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Grant
    Filed: December 6, 2019
    Date of Patent: September 7, 2021
    Assignee: Purdue Pharma L.P.
    Inventors: Jiangchao Yao, John W. F. Whitehead, Naoki Tsuno, Kouki Fuchino
  • Publication number: 20200223847
    Abstract: The invention relates to Substituted-Quinoxaline-Type Bridged-Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Application
    Filed: December 6, 2019
    Publication date: July 16, 2020
    Inventors: Jiangchao Yao, John W.F. Whitehead, Naoki Tsuno, Kouki Fuchino
  • Patent number: 10519156
    Abstract: Compounds of Formula (I): where R1, R2, R5, a, and b are disclosed herein, and pharmaceutically acceptable derivatives thereof, compositions thereof, and methods to treat or prevent a condition (such as pain) thereof. The disclosure also provides compounds of formula QB or O2 and their utility in manufacture processes in obtaining compounds of Formula (I).
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: December 31, 2019
    Assignee: Purdue Pharma L.P.
    Inventors: Jiangchao Yao, John W. F. Whitehead, Naoki Tsuno, Kouki Fuchino
  • Patent number: 10217543
    Abstract: Provided are: a transparent electroconductive film with good transparency, wherein the transparent electroconductive film has antiblocking properties that can withstand roll-to-roll manufacturing, and white haze on the transparent electroconductive film side is reduced. Also provided is a touch sensor in which the transparent electroconductive film is used. This transparent electroconductive film includes a transparent substrate 1 and a transparent electroconductive film 13 formed on one side of the transparent substrate, wherein the arithmetic mean surface roughness Ra in a 452×595 ?m field of view on the surface of the transparent electroconductive film 13 is greater than 0 nm and no more than 10 nm, and the arithmetic mean surface roughness Ra in a 452×595 ?m field of view on the surface of the transparent substrate 1 on which the transparent electroconductive film 13 is not formed is greater than 5 nm and less than 100 nm.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: February 26, 2019
    Assignee: NITTO DENKO CORPORATION
    Inventors: Motoki Haishi, Naoki Tsuno
  • Publication number: 20180370971
    Abstract: The invention relates to Substituted-Quinoxaline-Type Bridged-Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Application
    Filed: September 4, 2018
    Publication date: December 27, 2018
    Inventors: Jiangchao Yao, John W.F. Whitehead, Naoki Tsuno, Kouki Fuchino
  • Patent number: 10118927
    Abstract: The disclosure relates to Substituted Piperidin-4-amino-Type Compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof wherein R1, R2, R3, Q1, Q2, E1, E2, A, B, D, W, Z, a, b, n, and x are as defined herein, compositions comprising an effective amount of a Substituted Piperidin-4-amino-Type Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted Piperidin-4-amino-Type Compound.
    Type: Grant
    Filed: December 23, 2013
    Date of Patent: November 6, 2018
    Assignee: Purdue Pharma L.P.
    Inventors: Kevin Brown, Dawit Tadesse, Nobuyuki Tanaka, Naoki Tsuno, Xiaoming Zhou
  • Publication number: 20180155511
    Abstract: A laminate roll that is an elongated laminate wound in a form of a roll, wherein the laminate includes a transparent electrically conductive film including a polycycloolefin film and a transparent electrically conductive layer, and inclination of the direction of the slow axis of the polycycloolefin film with respect to the longitudinal direction of the elongated laminate falls within a range of±2° over the entire elongated laminate except opposite end portions thereof each of which accounts for 5% of the entire width of the elongated laminate.
    Type: Application
    Filed: April 14, 2016
    Publication date: June 7, 2018
    Inventors: Kentaro TAKEDA, Naoki TSUNO, Hidehiko ANDO, Akinori NISHIMURA, Takami HIKITA
  • Publication number: 20180148449
    Abstract: The invention relates to Substituted-Quinoxaline-Type Bridged-Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Application
    Filed: January 23, 2018
    Publication date: May 31, 2018
    Inventors: Jiangchao Yao, John W.F. Whitehead, Naoki Tsuno, Kouki Fuchino
  • Patent number: 9890164
    Abstract: Compounds of Formula (I): where R1, R2, R5, a, and b are disclosed herein, and pharmaceutically acceptable derivatives thereof (a “Substituted-Quinoxaline-Type Bridged-Piperidine Compound”), compositions comprising an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Bridged-Piperidine Compound.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: February 13, 2018
    Assignees: Purdue Pharma, L.P., Shionogi & Co., LTD.
    Inventors: Naoki Tsuno, Jiangchao Yao
  • Patent number: 9874987
    Abstract: Provided are a double-sided transparent conductive film which has blocking resistance and a low reflectance, and is inhibited from scattering reflected light to exhibit good visibility; a roll thereof; and a touch panel.
    Type: Grant
    Filed: January 29, 2015
    Date of Patent: January 23, 2018
    Assignee: NITTO DENKO CORPORATION
    Inventors: Naoki Hashimoto, Katsunori Takada, Kazuhiro Ikai, Shinya Hiraoka, Hiroki Kuramoto, Naoki Tsuno, Toru Umemoto, Hiroyuki Takao
  • Publication number: 20170338003
    Abstract: Provided are: a transparent electroconductive film with good transparency, wherein the transparent electroconductive film has antiblocking properties that can withstand roll-to-roll manufacturing, and white haze on the transparent electroconductive film side is reduced. Also provided is a touch sensor in which the transparent electroconductive film is used. This transparent electroconductive film includes a transparent substrate 1 and a transparent electroconductive film 13 formed on one side of the transparent substrate, wherein the arithmetic mean surface roughness Ra in a 452×595 ?m field of view on the surface of the transparent electroconductive film 13 is greater than 0 nm and no more than 10 nm, and the arithmetic mean surface roughness Ra in a 452×595 ?m field of view on the surface of the transparent substrate 1 on which the transparent electroconductive film 13 is not formed is greater than 5 nm and less than 100 nm.
    Type: Application
    Filed: December 2, 2015
    Publication date: November 23, 2017
    Applicant: NITTO DENKO CORPORATION
    Inventors: Motoki Haishi, Naoki Tsuno
  • Patent number: 9708338
    Abstract: The present invention is related to a compound represented by formula (I) wherein —X— is —NH— or —S—; —Z— is —O— or —S—; R3, R5 and R6 are each independently a hydrogen atom, substituted or unsubstituted alkyl, or the like; R7 is a cyano, substituted or unsubstituted amino, or the like; R7? is each independently a halogen; b is 0 or 1; or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising thereof.
    Type: Grant
    Filed: March 22, 2016
    Date of Patent: July 18, 2017
    Assignee: SHIONOGI & CO., LTD.
    Inventors: Akira Yukimasa, Naoki Tsuno, Motohiro Fujiu, Hiroki Yamaguchi, Hiromi Kudo, Tatsuhiko Ueno, Yusuke Ichihashi, Takatsugu Inoue, Shinji Suzuki
  • Patent number: 9609745
    Abstract: A transparent conductive film includes a film base, a cured resin layer formed at one side of the film base, and an indium composite oxide layer laminated at a side of the cured resin layer opposite to the film base. The indium composite oxide layer has a thickness of 20 nm to 50 nm. The cured resin layer has a plurality of spherical particles and a binder resin layer which fixes the plurality of spherical particles to the film base. A difference w?d between a mode particle size w and a thickness d of the binder resin layer is greater than zero and less than or equal to 1.2 ?m, where w is a mode particle size of the spherical particles and d is a thickness of the binder resin layer.
    Type: Grant
    Filed: December 10, 2012
    Date of Patent: March 28, 2017
    Assignee: NITTO DENKO CORPORATION
    Inventors: Katsunori Takada, Kazuhiro Ikai, Hiroki Kuramoto, Hiroyuki Takao, Naoki Tsuno
  • Patent number: 9607733
    Abstract: A double-sided transparent conductive film including a base material film, having an anti-blocking layer, an optical adjusting layer and a transparent conductive layer formed in this order on each of both sides of the base material film, wherein an anti-blocking layer containing particles is formed at least one of: a location between the base material film and one optical adjusting layer; and a location between the base material film and the other optical adjusting layer, the anti-blocking layer has a flat portion and protrusion portions caused by the particles, and a value obtained by subtracting a thickness of the flat portion of the anti-blocking layer from a mode diameter of the particles is larger than a thickness of the optical adjusting layer.
    Type: Grant
    Filed: May 20, 2014
    Date of Patent: March 28, 2017
    Assignee: NITTO DENKO CORPORATION
    Inventors: Katsunori Takada, Naoki Hashimoto, Shinya Hiraoka, Kazuhiro Ikai, Hiroki Kuramoto, Hiroyuki Takao, Naoki Tsuno, Toru Umemoto
  • Publication number: 20170010709
    Abstract: Provided are a double-sided transparent conductive film which has blocking resistance and a low reflectance, and is inhibited from scattering reflected light to exhibit good visibility; a roll thereof; and a touch panel.
    Type: Application
    Filed: January 29, 2015
    Publication date: January 12, 2017
    Applicant: NITTO DENKO CORPORATION
    Inventors: Naoki HASHIMOTO, Katsunori TAKADA, Kazuhiro IKAI, Shinya HIRAOKA, Hiroki KURAMOTO, Naoki TSUNO, Toru UMEMOTO, Hiroyuki TAKAO
  • Patent number: 9527840
    Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: December 27, 2016
    Assignees: Purdue Pharma L.P., Shionogi & Co. Ltd.
    Inventors: Kouki Fuchino, R. Richard Goehring, Bin Shao, Yoshiyuki Taoda, Naoki Tsuno, John William Frank Whitehead, Jiangchao Yao
  • Publication number: 20160272640
    Abstract: The disclosure relates to Substituted Piperidin-4-amino-Type Compounds of Formula (I) and pharmaceutically acceptable salts and solvates thereof wherein R1, R2, R3, Q1, Q2, E1, E2, A, B, D, W, Z, a, b, n, and x are as defined herein, compositions comprising an effective amount of a Substituted Piperidin-4-amino-Type Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted Piperidin-4-amino-Type Compound.
    Type: Application
    Filed: December 23, 2013
    Publication date: September 22, 2016
    Applicant: Shionogi & Co., Ltd.
    Inventors: Kevin Brown, Dawit Tadesse, Nobuyuki Tanaka, Naoki Tsuno, Xiaoming Zhou
  • Publication number: 20160200721
    Abstract: The present invention is related to a compound represented by formula (I) wherein —X— is —NH— or —S—; —Z— is —O— or —S—; R3, R5 and R6 are each independently a hydrogen atom, substituted or unsubstituted alkyl, or the like; R7 is a cyano, substituted or unsubstituted amino, or the like; R7? is each independently a halogen; b is 0 or 1; or a pharmaceutically acceptable salt thereof, or a pharmaceutical composition comprising thereof.
    Type: Application
    Filed: March 22, 2016
    Publication date: July 14, 2016
    Applicant: Shionogi & Co., Ltd.
    Inventors: Akira YUKIMASA, Naoki TSUNO, Motohiro FUJIU, Hiroki YAMAGUCHI, Hiromi KUDO, Tatsuhiko UENO, Yusuke ICHIHASHI, Takatsugu INOUE, Shinji SUZUKI
  • Publication number: 20160159785
    Abstract: The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.
    Type: Application
    Filed: February 11, 2016
    Publication date: June 9, 2016
    Inventors: Kouki FUCHINO, R. Richard Goehring, Akira Matsumura, Bin Shao, Yoshiyuki Taoda, Naoki Tsuno, John William Frank Whitehead, Jiangchao Yao