Patents by Inventor Naoko Takaoka
Naoko Takaoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11794191Abstract: A dispensing tip holder is used when a dispensing tip is attached to a tip of a pipette, and includes a peripheral wall having a shape surrounding an outer peripheral surface of the dispensing tip, and an insertion portion having an insertion opening into which the dispensing tip is to be inserted. The peripheral wall has a first end into which the dispensing tip is to be inserted, and has a second end provided at a position opposite to the first end. The insertion portion is formed in the peripheral wall such that an outer peripheral surface of the dispensing tip abuts against an edge of the insertion opening, and is formed in the peripheral wall such that a tip of the dispensing tip does not project from the second end of the peripheral wall, when the dispensing tip is inserted into the insertion opening from the first end.Type: GrantFiled: July 30, 2020Date of Patent: October 24, 2023Assignee: SHIMADZU CORPORATIONInventors: Masamitsu Shikata, Kenji Ninomiya, Naoko Takaoka, Shinichiro Kobayashi
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Patent number: 11739376Abstract: A method for testing target nucleic acid includes the steps from (1) through (5) below: (1) mixing a specimen containing target nucleic acid with positive control nucleic acid to obtain a specimen mixture of the specimen and the positive control nucleic acid; (2) mixing the specimen mixture with a PCR buffer solution containing a surfactant to obtain a buffer solution mixture; (3) adding a portion of the buffer mixture to a solid composition for PCR control containing DNA polymerase, positive control nucleic acid, and PCR reaction control nucleic acid; (4) adding a portion of the buffer mixture to a solid composition for PCR reaction containing DNA polymerase and one or more kinds of PCR primer pair; and (5) detecting a PCR product generated as a result of the steps (3) and (4).Type: GrantFiled: September 17, 2020Date of Patent: August 29, 2023Assignee: SHIMADZU CORPORATIONInventor: Naoko Takaoka
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Publication number: 20210114018Abstract: A reaction vessel has plural wells each configured to accommodate a sample on the same plane or on the same straight line. Among the wells of a well plate, a specific well other than a well at a center of point symmetry is an orientation recognizing well in which a fluorescent dye is placed. The reaction vessel can identify a position of the orientation recognizing well by using fluorescence emitted from the fluorescent dye, and can thereby recognize an orientation of the reaction vessel.Type: ApplicationFiled: October 18, 2019Publication date: April 22, 2021Applicant: SHIMADZU CORPORATIONInventors: Naoko TAKAOKA, Masamitsu SHIKATA, Kenji NINOMIYA, Shinichiro KOBAYASHI
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Publication number: 20210087608Abstract: A method for testing target nucleic acid includes the steps from (1) through (5) below: (1) mixing a specimen containing target nucleic acid with positive control nucleic acid to obtain a specimen mixture of the specimen and the positive control nucleic acid; (2) mixing the specimen mixture with a PCR buffer solution containing a surfactant to obtain a buffer solution mixture; (3) adding a portion of the buffer mixture to a solid composition for PCR control containing DNA polymerase, positive control nucleic acid, and PCR reaction control nucleic acid; (4) adding a portion of the buffer mixture to a solid composition for PCR reaction containing DNA polymerase and one or more kinds of PCR primer pair; and (5) detecting a PCR product generated as a result of the steps (3) and (4).Type: ApplicationFiled: September 17, 2020Publication date: March 25, 2021Applicant: SHIMADZU CORPORATIONInventor: Naoko TAKAOKA
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Publication number: 20210031205Abstract: A dispensing tip holder is used when a dispensing tip is attached to a tip of a pipette, and includes a peripheral wall having a shape surrounding an outer peripheral surface of the dispensing tip, and an insertion portion having an insertion opening into which the dispensing tip is to be inserted. The peripheral wall has a first end into which the dispensing tip is to be inserted, and has a second end provided at a position opposite to the first end. The insertion portion is formed in the peripheral wall such that an outer peripheral surface of the dispensing tip abuts against an edge of the insertion opening, and is formed in the peripheral wall such that a tip of the dispensing tip does not project from the second end of the peripheral wall, when the dispensing tip is inserted into the insertion opening from the first end.Type: ApplicationFiled: July 30, 2020Publication date: February 4, 2021Applicant: SHIMADZU CORPORATIONInventors: Masamitsu SHIKATA, Kenji NINOMIYA, Naoko TAKAOKA, Shinichiro KOBAYASHI
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Publication number: 20200290051Abstract: To improve a sealing property of a reaction container over a period before and after implementing gene amplification processing. A gene amplification device includes: a reaction container holder having a container insertion part into which a main body of a reaction container including the main body and a lid attached to an upper portion of the main body is inserted, the reaction container holder having a function of raising and lowering a temperature of the reaction container inserted into the container insertion part; and a heat seal part disposed near an contacting portion between the main body and the lid of the reaction container inserted into the container insertion part of the reaction container holder, the heat seal part heating a temperature of the contacting portion to a temperature higher than a heatproof temperature of the main body or the lid of the reaction container.Type: ApplicationFiled: March 14, 2019Publication date: September 17, 2020Applicant: SHIMADZU CORPORATIONInventors: Kenji Ninomiya, Masamitsu Shikata, Naoko Takaoka, Shinichiro Kobayashi
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Publication number: 20190022658Abstract: A gene measurement apparatus includes: a temperature control block that is provided with, on its upper surface, a plurality of reaction vessel wells each being used to house a reaction vessel, and that performs temperature treatment on a specimen in the reaction vessel by controlling temperature of the plurality of reaction vessel wells using a heating element or a cooling element; and a reaction vessel detector configured to detect whether the reaction vessel is housed in each of the plurality of reaction vessel wells of the temperature control block before the temperature treatment is started.Type: ApplicationFiled: July 20, 2018Publication date: January 24, 2019Applicant: SHIMADZU CORPORATIONInventors: Kenji NINOMIYA, Masamitsu SHIKATA, Naoko TAKAOKA, Shinichiro KOBAYASHI
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Patent number: 10080551Abstract: A stool collection container includes: a stool collection container main body having a structure in which a stick holder for holding a stool collection stick is detachably mounted on one end side while the stool collection part and the stool collection stick are housed inside; and a collection needle penetrating through a wall surface of the another end side of the stool collection container main body so that a tip thereof is inserted into the stool collection container main body, the collection needle being provided so as to be detachable from the stool collection container main body. When the stick holder is mounted on one end side of the stool collection container main body, the tip of the collection needle is inserted into the opening of the stool collection part housed inside the stool collection container main body.Type: GrantFiled: January 13, 2017Date of Patent: September 25, 2018Assignee: SHIMADZU CORPORATIONInventors: Masamitsu Shikata, Naoko Takaoka
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Publication number: 20180199922Abstract: A stool collection container includes: a stool collection container main body having a structure in which a stick holder for holding a stool collection stick is detachably mounted on one end side while the stool collection part and the stool collection stick are housed inside; and a collection needle penetrating through a wall surface of the another end side of the stool collection container main body so that a tip thereof is inserted into the stool collection container main body, the collection needle being provided so as to be detachable from the stool collection container main body. When the stick holder is mounted on one end side of the stool collection container main body, the tip of the collection needle is inserted into the opening of the stool collection part housed inside the stool collection container main body.Type: ApplicationFiled: January 13, 2017Publication date: July 19, 2018Applicant: SHIMADZU CORPORATIONInventors: Masamitsu SHIKATA, Naoko TAKAOKA
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Patent number: 6165724Abstract: The object of the present invention is to provide a simple, rapid and highly sensitive method of examining EHEC or VTEC in the examination of food poisoning and diarrhea. In the present invention, the oligonucleotides of SEQ ID NOS: 1-9 hybridizing selectively with a Vero toxin gene from EHEC (or VTEC) or with an O antigen-synthesizing region gene from pathogenic E. coli O157 are prepared and used as primers for gene amplification. By this method, bacteria producing O157 as one of the pathogenic factors in these bacteria and E. coli capable of producing Vero toxin can be selectively detected.Type: GrantFiled: May 19, 1999Date of Patent: December 26, 2000Assignee: Shimadzu CorporationInventors: Shigeru Fukushima, Naoko Takaoka