Patents by Inventor Naoko Takaoka

Naoko Takaoka has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11794191
    Abstract: A dispensing tip holder is used when a dispensing tip is attached to a tip of a pipette, and includes a peripheral wall having a shape surrounding an outer peripheral surface of the dispensing tip, and an insertion portion having an insertion opening into which the dispensing tip is to be inserted. The peripheral wall has a first end into which the dispensing tip is to be inserted, and has a second end provided at a position opposite to the first end. The insertion portion is formed in the peripheral wall such that an outer peripheral surface of the dispensing tip abuts against an edge of the insertion opening, and is formed in the peripheral wall such that a tip of the dispensing tip does not project from the second end of the peripheral wall, when the dispensing tip is inserted into the insertion opening from the first end.
    Type: Grant
    Filed: July 30, 2020
    Date of Patent: October 24, 2023
    Assignee: SHIMADZU CORPORATION
    Inventors: Masamitsu Shikata, Kenji Ninomiya, Naoko Takaoka, Shinichiro Kobayashi
  • Patent number: 11739376
    Abstract: A method for testing target nucleic acid includes the steps from (1) through (5) below: (1) mixing a specimen containing target nucleic acid with positive control nucleic acid to obtain a specimen mixture of the specimen and the positive control nucleic acid; (2) mixing the specimen mixture with a PCR buffer solution containing a surfactant to obtain a buffer solution mixture; (3) adding a portion of the buffer mixture to a solid composition for PCR control containing DNA polymerase, positive control nucleic acid, and PCR reaction control nucleic acid; (4) adding a portion of the buffer mixture to a solid composition for PCR reaction containing DNA polymerase and one or more kinds of PCR primer pair; and (5) detecting a PCR product generated as a result of the steps (3) and (4).
    Type: Grant
    Filed: September 17, 2020
    Date of Patent: August 29, 2023
    Assignee: SHIMADZU CORPORATION
    Inventor: Naoko Takaoka
  • Publication number: 20210114018
    Abstract: A reaction vessel has plural wells each configured to accommodate a sample on the same plane or on the same straight line. Among the wells of a well plate, a specific well other than a well at a center of point symmetry is an orientation recognizing well in which a fluorescent dye is placed. The reaction vessel can identify a position of the orientation recognizing well by using fluorescence emitted from the fluorescent dye, and can thereby recognize an orientation of the reaction vessel.
    Type: Application
    Filed: October 18, 2019
    Publication date: April 22, 2021
    Applicant: SHIMADZU CORPORATION
    Inventors: Naoko TAKAOKA, Masamitsu SHIKATA, Kenji NINOMIYA, Shinichiro KOBAYASHI
  • Publication number: 20210087608
    Abstract: A method for testing target nucleic acid includes the steps from (1) through (5) below: (1) mixing a specimen containing target nucleic acid with positive control nucleic acid to obtain a specimen mixture of the specimen and the positive control nucleic acid; (2) mixing the specimen mixture with a PCR buffer solution containing a surfactant to obtain a buffer solution mixture; (3) adding a portion of the buffer mixture to a solid composition for PCR control containing DNA polymerase, positive control nucleic acid, and PCR reaction control nucleic acid; (4) adding a portion of the buffer mixture to a solid composition for PCR reaction containing DNA polymerase and one or more kinds of PCR primer pair; and (5) detecting a PCR product generated as a result of the steps (3) and (4).
    Type: Application
    Filed: September 17, 2020
    Publication date: March 25, 2021
    Applicant: SHIMADZU CORPORATION
    Inventor: Naoko TAKAOKA
  • Publication number: 20210031205
    Abstract: A dispensing tip holder is used when a dispensing tip is attached to a tip of a pipette, and includes a peripheral wall having a shape surrounding an outer peripheral surface of the dispensing tip, and an insertion portion having an insertion opening into which the dispensing tip is to be inserted. The peripheral wall has a first end into which the dispensing tip is to be inserted, and has a second end provided at a position opposite to the first end. The insertion portion is formed in the peripheral wall such that an outer peripheral surface of the dispensing tip abuts against an edge of the insertion opening, and is formed in the peripheral wall such that a tip of the dispensing tip does not project from the second end of the peripheral wall, when the dispensing tip is inserted into the insertion opening from the first end.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 4, 2021
    Applicant: SHIMADZU CORPORATION
    Inventors: Masamitsu SHIKATA, Kenji NINOMIYA, Naoko TAKAOKA, Shinichiro KOBAYASHI
  • Publication number: 20200290051
    Abstract: To improve a sealing property of a reaction container over a period before and after implementing gene amplification processing. A gene amplification device includes: a reaction container holder having a container insertion part into which a main body of a reaction container including the main body and a lid attached to an upper portion of the main body is inserted, the reaction container holder having a function of raising and lowering a temperature of the reaction container inserted into the container insertion part; and a heat seal part disposed near an contacting portion between the main body and the lid of the reaction container inserted into the container insertion part of the reaction container holder, the heat seal part heating a temperature of the contacting portion to a temperature higher than a heatproof temperature of the main body or the lid of the reaction container.
    Type: Application
    Filed: March 14, 2019
    Publication date: September 17, 2020
    Applicant: SHIMADZU CORPORATION
    Inventors: Kenji Ninomiya, Masamitsu Shikata, Naoko Takaoka, Shinichiro Kobayashi
  • Publication number: 20190022658
    Abstract: A gene measurement apparatus includes: a temperature control block that is provided with, on its upper surface, a plurality of reaction vessel wells each being used to house a reaction vessel, and that performs temperature treatment on a specimen in the reaction vessel by controlling temperature of the plurality of reaction vessel wells using a heating element or a cooling element; and a reaction vessel detector configured to detect whether the reaction vessel is housed in each of the plurality of reaction vessel wells of the temperature control block before the temperature treatment is started.
    Type: Application
    Filed: July 20, 2018
    Publication date: January 24, 2019
    Applicant: SHIMADZU CORPORATION
    Inventors: Kenji NINOMIYA, Masamitsu SHIKATA, Naoko TAKAOKA, Shinichiro KOBAYASHI
  • Patent number: 10080551
    Abstract: A stool collection container includes: a stool collection container main body having a structure in which a stick holder for holding a stool collection stick is detachably mounted on one end side while the stool collection part and the stool collection stick are housed inside; and a collection needle penetrating through a wall surface of the another end side of the stool collection container main body so that a tip thereof is inserted into the stool collection container main body, the collection needle being provided so as to be detachable from the stool collection container main body. When the stick holder is mounted on one end side of the stool collection container main body, the tip of the collection needle is inserted into the opening of the stool collection part housed inside the stool collection container main body.
    Type: Grant
    Filed: January 13, 2017
    Date of Patent: September 25, 2018
    Assignee: SHIMADZU CORPORATION
    Inventors: Masamitsu Shikata, Naoko Takaoka
  • Publication number: 20180199922
    Abstract: A stool collection container includes: a stool collection container main body having a structure in which a stick holder for holding a stool collection stick is detachably mounted on one end side while the stool collection part and the stool collection stick are housed inside; and a collection needle penetrating through a wall surface of the another end side of the stool collection container main body so that a tip thereof is inserted into the stool collection container main body, the collection needle being provided so as to be detachable from the stool collection container main body. When the stick holder is mounted on one end side of the stool collection container main body, the tip of the collection needle is inserted into the opening of the stool collection part housed inside the stool collection container main body.
    Type: Application
    Filed: January 13, 2017
    Publication date: July 19, 2018
    Applicant: SHIMADZU CORPORATION
    Inventors: Masamitsu SHIKATA, Naoko TAKAOKA
  • Patent number: 6165724
    Abstract: The object of the present invention is to provide a simple, rapid and highly sensitive method of examining EHEC or VTEC in the examination of food poisoning and diarrhea. In the present invention, the oligonucleotides of SEQ ID NOS: 1-9 hybridizing selectively with a Vero toxin gene from EHEC (or VTEC) or with an O antigen-synthesizing region gene from pathogenic E. coli O157 are prepared and used as primers for gene amplification. By this method, bacteria producing O157 as one of the pathogenic factors in these bacteria and E. coli capable of producing Vero toxin can be selectively detected.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: December 26, 2000
    Assignee: Shimadzu Corporation
    Inventors: Shigeru Fukushima, Naoko Takaoka