Patents by Inventor Naoko Takebe

Naoko Takebe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR COLLECTING AND USING PLACENTA CORD BLOOD STEM CELLS
    Publication number: 20200138872
    Abstract: An innovative method of collecting cord blood stem cells from an isolated mammalian non-exsanguinated or partially exsanguinated placenta by placental perfusion is described and also an easy method for safe long duration cold storage of the placenta. Placental perfusion can include perfusing the isolated placenta with a pulsatile flow of perfusion solution, for example, using a pulsatile or peristaltic pump or device. The stem cells can then be isolated from the perfusate. Significantly increased amounts of CD133+ stem cells can be collected from the perfusate. The perfusion solution can include an anticoagulant. The isolated mammalian placenta need not be treated with an anticoagulant prior to perfusing. The isolated placenta can be free from an anticoagulant prior to perfusing.
    Type: Application
    Filed: December 16, 2019
    Publication date: May 7, 2020
    Applicant: CELULARITY, INC.
    Inventor: Naoko TAKEBE
  • Methods for collecting and using placenta cord blood stem cells
    Patent number: 10548926
    Abstract: An innovative method of collecting cord blood stem cells from an isolated mammalian non-exsanguinated or partially exsanguinated placenta by placental perfusion is described and also an easy method for safe long duration cold storage of the placenta. Placental perfusion can include perfusing the isolated placenta with a pulsatile flow of perfusion solution, for example, using a pulsatile or peristaltic pump or device. The stem cells can then be isolated from the perfusate. Significantly increased amounts of CD133+ stem cells can be collected from the perfusate. The perfusion solution can include an anticoagulant. The isolated mammalian placenta need not be treated with an anticoagulant prior to perfusing. The isolated placenta can be free from an anticoagulant prior to perfusing.
    Type: Grant
    Filed: March 11, 2016
    Date of Patent: February 4, 2020
    Assignee: CELULARITY, INC.
    Inventor: Naoko Takebe
  • METHODS FOR COLLECTING AND USING PLACENTA CORD BLOOD STEM CELLS
    Publication number: 20160220618
    Abstract: An innovative method of collecting cord blood stem cells from an isolated mammalian non-exsanguinated or partially exsanguinated placenta by placental perfusion is described and also an easy method for safe long duration cold storage of the placenta. Placental perfusion can include perfusing the isolated placenta with a pulsatile flow of perfusion solution, for example, using a pulsatile or peristaltic pump or device. The stem cells can then be isolated from the perfusate. Significantly increased amounts of CD133+ stem cells can be collected from the perfusate. The perfusion solution can include an anticoagulant. The isolated mammalian placenta need not be treated with an anticoagulant prior to perfusing. The isolated placenta can be free from an anticoagulant prior to perfusing.
    Type: Application
    Filed: March 11, 2016
    Publication date: August 4, 2016
    Applicant: ANTHROGENESIS CORPORATION
    Inventor: Naoko TAKEBE
  • Methods for collecting and using placenta cord blood stem cell
    Patent number: 8329468
    Abstract: An innovative method of collecting cord blood stem cells from an isolated mammalian non-exsanguinated or partially exsanguinated placenta by placental perfusion is described and also an easy method for safe long duration cold storage of the placenta. Placental perfusion can include perfusing the isolated placenta with a pulsatile flow of perfusion solution, for example, using a pulsatile or peristaltic pump or device. The stem cells can then be isolated from the perfusate. Significantly increased amounts of CD133+ stem cells can be collected from the perfusate. The perfusion solution can include an anticoagulant. The isolated mammalian placenta need not be treated with an anticoagulant prior to perfusing. The isolated placenta can be free from an anticoagulant prior to perfusing.
    Type: Grant
    Filed: November 10, 2008
    Date of Patent: December 11, 2012
    Assignee: Cord Blood Science Inc.
    Inventor: Naoko Takebe
  • Breast cancer resistance protein (BCRP) and antibodies thereto
    Patent number: 7803917
    Abstract: The present invention provides a breast cancer resistance polynucleotide and protein of Macaca mulata (rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: September 28, 2010
    Assignee: University of Maryland
    Inventor: Naoko Takebe
  • METHODS FOR COLLECTING AND USING PLACENTA CORD BLOOD STEM CELLS
    Publication number: 20090123437
    Abstract: An innovative method of collecting cord blood stem cells from an isolated mammalian non-exsanguinated or partially exsanguinated placenta by placental perfusion is described and also an easy method for safe long duration cold storage of the placenta. Placental perfusion can include perfusing the isolated placenta with a pulsatile flow of perfusion solution, for example, using a pulsatile or peristaltic pump or device. The stem cells can then be isolated from the perfusate. Significantly increased amounts of CD133+ stem cells can be collected from the perfusate. The perfusion solution can include an anticoagulant. The isolated mammalian placenta need not be treated with an anticoagulant prior to perfusing. The isolated placenta can be free from an anticoagulant prior to perfusing.
    Type: Application
    Filed: November 10, 2008
    Publication date: May 14, 2009
    Inventor: Naoko TAKEBE
  • BREAST CANCER RESISTANCE PROTEIN (BCRP) AND ANTIBODIES THERETO
    Publication number: 20090098572
    Abstract: The present invention provides a breast cancer resistance polynucleotide and protein of Macaca mulata (rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.
    Type: Application
    Filed: November 6, 2008
    Publication date: April 16, 2009
    Inventor: Naoko TAKEBE
  • Breast cancer resistance protein (BCRP) and antibodies thereto
    Patent number: 7465788
    Abstract: The present invention provides a breast cancer resistance polynucleotide and protein of Macaca mulata (rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.
    Type: Grant
    Filed: January 18, 2006
    Date of Patent: December 16, 2008
    Assignee: University of Maryland
    Inventor: Naoko Takebe
  • Rhesus BCRP and antibodies thereto
    Publication number: 20060160139
    Abstract: The present invention provides a breast cancer resistance polynucleotide and protein of Macaca mulata (rhesus monkey) and uses thereof. The present invention also provides anti-BCRP antibodies and uses thereof, particularly as a hematopoietic stem cell marker.
    Type: Application
    Filed: January 18, 2006
    Publication date: July 20, 2006
    Inventor: Naoko Takebe