Patents by Inventor Naoko Tanese

Naoko Tanese has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tata-binding protein associated factor, nucleic acids
    Patent number: 5637686
    Abstract: TATA-binding protein associated factors, TAFs, nuclear proteins involved in RNA polymerase I, II, and III transcription, and nucleic acids encoding TAFs are disclosed. The disclosed methods and compositions find use in developing pharmaceuticals, diagnosis and therapy.
    Type: Grant
    Filed: May 9, 1996
    Date of Patent: June 10, 1997
    Assignee: The Regents of the University of California
    Inventors: Robert Tjian, Lucio Comai, Brian D. Dynlact, Timothy Hoey, Siegfried Ruppert, Naoko Tanese, Edith Wang, Robert O. J. Weinzierl
  • TATA-binding protein associated factors drug screens
    Patent number: 5534410
    Abstract: TATA-binding protein associated factors, TAFs, nuclear proteins involved in RNA polymerase I, II, and III transcription, and nucleic acids encoding TAFs are disclosed. The disclosed methods and compositions find use in developing pharmaceuticals, diagnosis and therapy.
    Type: Grant
    Filed: January 28, 1994
    Date of Patent: July 9, 1996
    Assignee: The Regents of the University of California
    Inventors: Robert Tjian, Lucio Comai, Brian D. Dynlacht, Timothy Hoey, Siegfried Ruppert, Naoko Tanese, Edith Wang, Robert O. J. Weinzierl
  • Expression of human immunodeficiency virus (HIV) reverse transcriptase
    Patent number: 5256554
    Abstract: This invention describes pHRT25, a plasmid containing a modified pol gene of the Human Immunodeficiency Virus Type 1 (HIV-1), formerly HTLV-III, under control of an inducible trp promoter. Methods of expressing reverse transcriptase activity using pHRT25 in E. coli are described.
    Type: Grant
    Filed: December 2, 1991
    Date of Patent: October 26, 1993
    Assignees: The Trustees of Columbia University in the City of New York, The Dana Farber Cancer Institute
    Inventors: Stephen P. Goff, Naoko Tanese, William A. Haseltine
  • Expression of human immunodeficiency virus (HIV) reverse transcriptase
    Patent number: 5202259
    Abstract: This invention provides a plasmid identified as pHRTRX2 and deposited in E. coli HB101 under ATCC Accession No. 67828. The invention also provides for a polypeptide having HIV reverse transcriptase activity and for a method by which the polypeptide can be prepared which comprises growing a host cell comprising the plasmid pHRTRX2 under suitable conditions permitting production of the polypeptide and recovering the resulting polypeptide.
    Type: Grant
    Filed: December 28, 1988
    Date of Patent: April 13, 1993
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Stephen P. Goff, Naoko Tanese
  • Expression of enzymatically active reverse transcriptase
    Patent number: 4943531
    Abstract: This invention provides a plasmic which, when introduced into a suitable host cell and grown under appropriate conditions, effects expression of a gene on the plasmid and production of a polypeptide having reverse transcriptase activity. The plasmid is a double-stranded DNA molecule which includes in a 5' to 3' order the following: a DNA sequence which includes an inducible promoter; a DNA sequence which includes an ATG initiation condon; the central portion of the Moloney murine leukemia virus (MuLV) pol gene, said central portion including a DNA sequence which encodes the polypeptide having reverse transcriptase activity; a DNA sequence which contains a gene associated with a selectable or identifiable phenotypic trait which is manifested when the vector is present in the host cell; and a DNA sequence which contains an origin of replication from a bacterial plasmid capable of autonomous replication in the host cell.
    Type: Grant
    Filed: May 6, 1985
    Date of Patent: July 24, 1990
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Stephen P. Goff, Naoko Tanese, Monica J. Roth