Abstract: RNA molecules for RNA interference to target a mutant allele with a point mutation, wherein the molecule has a nucleotide sequence complementary to a nucleotide sequence of a coding region of the mutant allele; and when counted from the base at the 5?-end in the nucleotide sequence complementary to the sequence of the mutant allele: a base at position 5 or 6 is mismatched with a base in the mutant allele; a base at position 10 or 11 is at the position of the point mutation and is identical to the base at the position of the point mutation in the mutant allele; the group at the 2?-position of the pentose in the ribonucleotide at position 8 is modified with OCH3, halogen, or LNA; and the group at the 2?-position of the pentose in the ribonucleotide at position 7 is not modified with any of OCH3, halogen, and LNA.

Abstract: Provided a microdevice capable of performing analysis quickly and at a high level of sensitivity even when a minute amount of sample solution is used. The microdevice is equipped with a rotation board, a reaction field provided on the rotation board, and an introduction portion for introducing a solution into the reaction field. The microdevice is characterized in that the following angle is always 45 to 90°: an angle of a part of a wall surface of the reaction field where the centrifugal force has the greatest effect with respect to the direction of the centrifugal force generated when the rotation board is rotated.

Abstract: In order to realize an accurate electrochemical measurement without a peak caused due to a silver chloride complex ion, an electrochemical measurement electrode of the present invention which measures an electrochemical active substance in a sample solution containing a chloride ion includes (i) a working electrode, (ii) a reference electrode made of silver and silver chloride, and (iii) a silver ion capturing material which captures a silver ion out of a silver chloride complex ion generated in the reference electrode.

Abstract: The present invention provides a biosensor including a working electrode or working electrodes on which a reaction material or a bonding material is immobilized, where the reaction material is reactive with a target material so as to produce a product, and the bonding material is bondable with a target material; a counter electrode; and a reaction section for holding a sample liquid containing the target material, the working electrode and the counter electrode being provided on a bottom surface of the reaction section, and the working electrode occupying the bottom surface of the reaction section by a ratio of 0.7 or greater.

Abstract: Provided a microdevice capable of performing analysis quickly and at a high level of sensitivity even when a minute amount of sample solution is used. The microdevice is equipped with a rotation board, a reaction field provided on the rotation board, and an introduction portion for introducing a solution into the reaction field. The microdevice is characterized in that the following angle is always 45 to 90°: an angle of a part of a wall surface of the reaction field where the centrifugal force has the greatest effect with respect to the direction of the centrifugal force generated when the rotation board is rotated.

Abstract: In order to realize an accurate electrochemical measurement without a peak caused due to a silver chloride complex ion, an electrochemical measurement electrode of the present invention which measures an electrochemical active substance in a sample solution containing a chloride ion includes (i) a working electrode, (ii) a reference electrode made of silver and silver chloride, and (iii) a silver ion capturing material which captures a silver ion out of a silver chloride complex ion generated in the reference electrode.