Abstract: An axial fan rotates around a rotating shaft. The axial fan includes a hub, and a plurality of blades extending in a radial direction from the hub. Each blade includes a leading edge, a trailing edge including a depression, and a reinforcing protrusion located at least forwardmost and having a wall thickness thicker than a surrounding portion. As viewed along a rotating shaft direction, when a first virtual line and a second virtual line perpendicular to the radial direction are drawn, the reinforcing protrusion extends radially inside of the first virtual line and extends radially outside of the second virtual line, the first virtual line and the second virtual line respectively pass through a rearmost first endpoint in the rotation direction on a radially inside of a rear end that substantially overlaps the depression, and a rearmost second endpoint on a radially outside of the rear end.

Abstract: Provided herein are methods for reducing, minimizing, or controlling drug-drug interactions resulting from administration of a first drug that is vadadustat (i.e., {[5-(3- chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid (Compound 1)) and a second drug (for example, a drug comprising a multivalent cation such as calcium, iron, magnesium, lanthanum, aluminum, and the like; a statin drug; sulfasalazine; or furosemide), to a subject.