Abstract: A biological information measurement device adapted to be attached on an upper arm of a human body and used thereon includes a belt portion adapted to be wound around the upper arm, electrocardiographic measurement means including a plurality of electrodes for detecting an electrocardiographic signal of the human body, pulse wave measurement means including a pulse wave sensor for detecting a pulse wave of the human body, heartbeat vibration measurement means including a vibration sensor for detecting vibration caused by beating of a heart of the human body, and an analysis processing unit configured to calculate a pre-ejection time and a pulse transit time of the heart based on time series data of the electrocardiographic signal, time series data of the pulse wave, and time series data of the vibration caused by the beating of the heart.

Abstract: A biological information measurement device includes a sensor unit that detects predetermined biological information related to an organ of a living body, an A/D conversion unit that converts a measurement signal output from the sensor unit into a digital signal, a storage unit that stores information including a digital signal related to the measurement signal output from the A/D conversion unit, an analysis processing unit that determines presence or absence of a suspicion of an abnormality in the organ by analyzing the digital signal, and a measurement control unit that changes a sampling frequency related to A/D conversion of the measurement signal under a predetermined condition when the analysis processing unit has determined that a suspicion of an abnormality is present in the organ.

Abstract: The present invention has as an object to provide a bone metabolism improving agent that improves bone metabolism in a chronic renal failure patient receiving blood purification therapy such as hemodialysis, hemofiltration and hemodiafiltration. An acetic acid- and/or acetate salt-free bone metabolism improving agent that contains citric acid and/or a citrate salt as electrolytes and further contains another/other electrolyte/electrolytes and glucose solely or in combination is provided. A bone metabolism improving agent formulated into a dialysate or a substitution fluid having effects of improving bone metabolism including bone metabolism improvement in adynamic bone disease and especially in bone agenesis is also provided.

Abstract: The present invention has as an object to provide a bone metabolism improving agent that improves bone metabolism in a chronic renal failure patient receiving blood purification therapy such as hemodialysis, hemofiltration and hemodiafiltration. An acetic acid- and/or acetate salt-free bone metabolism improving agent that contains citric acid and/or a citrate salt as electrolytes and further contains another/other electrolyte/electrolytes and glucose solely or in combination is provided. A bone metabolism improving agent formulated into a dialysate or a substitution fluid having effects of improving bone metabolism including bone metabolism improvement in adynamic bone disease and especially in bone agenesis is also provided.