Patents by Inventor Naomichi Matsumoto

Naomichi Matsumoto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for predicting risk of porencephaly or cerebral hemorrhage
    Patent number: 9580753
    Abstract: As a result of intensive screening on mutations of the COL4A2 gene in 35 Japanese patients with porencephaly, it was found that the COL4A2 gene is a causative gene for familial and sporadic porencephalies. Since an identical heterozygous mutation of the COL4A2 gene was found in both a porencephaly patient and healthy individuals, this pathogenic mutation is considered to be dominantly inherited with incomplete penetrance. It can be predicted that a living body having a COL4A2 gene mutation has a high risk of occurrence of porencephaly and/or cerebral hemorrhage.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: February 28, 2017
    Assignee: PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY
    Inventors: Naomichi Matsumoto, Hirotomo Saitsu
  • METHOD FOR PREDICTING RISK OF PORENCEPHALY OR CEREBRAL HEMORRHAGE
    Publication number: 20140315208
    Abstract: As a result of intensive screening on mutations of the COL4A2 gene in 35 Japanese patients with porencephaly, it was found that the COL4A2 gene is a causative gene for familial and sporadic porencephalies. Since an identical heterozygous mutation of the COL4A2 gene was found in both a porencephaly patient and healthy individuals, this pathogenic mutation is considered to be dominantly inherited with incomplete penetrance. It can be predicted that a living body having a COL4A2 gene mutation has a high risk of occurrence of porencephaly and/or cerebral hemorrhage.
    Type: Application
    Filed: October 29, 2012
    Publication date: October 23, 2014
    Applicant: Public University Corporation Yokohama City Univer
    Inventors: Naomichi Matsumoto, Hirotomo Saitsu
  • Probe for diagnosis of marfan syndrome and a method for screening using the probe
    Publication number: 20100209923
    Abstract: The purpose of this invention is to provide a probe for diagnosis of Marfan syndrome, which enables early diagnosis of Marfan syndrome, and to provide a method for screening using said probe. The invention is a probe for a Marfan Syndrome characterized by using a nucleic acid comprising following (a) or (b); (a) a nucleic acid comprising a base sequence represented by base numbers 1-180000 shown in SEQ ID No. 1 of the sequence listing, or (b) a nucleic acid in which a part of the base sequence of said base numbers 1-180000 is deleted, substituted or added, and having 80% homology with said base sequence.
    Type: Application
    Filed: February 2, 2010
    Publication date: August 19, 2010
    Applicants: NAGASAKI UNIVERSITY, INSTITUT NATIONAL DE LE SANTE ET DE LA RECHERCHE MEDICALE
    Inventors: Norio Niikawa, Naomichi Matsumoto, Catherine Boileau, Gwenaielle Beroud, Guillaume Jondeau
  • Probe for Diagnosis of Marfan Syndrome and a Method for Screening Using the Probe
    Publication number: 20080199856
    Abstract: The purpose of this invention is to provide a probe for diagnosis of Marfan syndrome, which enables early diagnosis of Marfan syndrome, and to provide a method for screening using said probe. The invention is a probe for a Marfan Syndrome characterized by using a nucleic acid comprising following (a) or (b); (a) a nucleic acid comprising a base sequence represented by base numbers 1-180000 shown in SEQ ID No. 1 of the sequence listing, or (b) a nucleic acid in which a part of the base sequence of said base numbers 1-180000 is deleted, substituted or added, and having 80% homology with said base sequence.
    Type: Application
    Filed: May 27, 2005
    Publication date: August 21, 2008
    Applicant: NAGASAKI UNIVERSITY
    Inventors: Norio Niikawa, Naomichi Matsumoto, Catherine Boileau, Gwenaielle Beroud, Guillaume Jondeau
  • Nucleic acid, probe comprising the nucleic acid and screening method using the probe
    Patent number: 7323301
    Abstract: A nucleic acid is (a) a nucleic acid comprising a base sequence shown in base numbers 1–39726 of SEQ ID NO: 1, or (b) a nucleic acid wherein a part of the bases 1–39726 of SEQ ID NO: 1 is deleted, substituted or added, and having a homology of 80% for the base sequence. Also, a probe comprises the above nucleic acid, and a screening is carried out by using such a probe.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: January 29, 2008
    Assignee: Nagasaki University
    Inventors: Naomichi Matsumoto, Norio Niikawa
  • Nucleic acid, probe comprising the nucleic acid and screening method using the probe
    Publication number: 20030162203
    Abstract: A nucleic acid is (a) a nucleic acid comprising a base sequence shown in a base sequence number 1-39726 of a sequence No.1 of a sequence table, or (b) a nucleic acid wherein a part of the base sequence of the base sequence number 1-39726 is deleted, substituted or added, and having a homology of 80% for the base sequence. Also, a probe comprises the above nucleic acid, and a screening is carried out by using such a probe.
    Type: Application
    Filed: December 4, 2002
    Publication date: August 28, 2003
    Applicant: Nagasaki University
    Inventors: Naomichi Matsumoto, Norio Niikawa