Abstract: The present disclosure provides a method for producing a frozen body of a three-dimensional tissue aggregate of retinal pigment epithelial cells, the method including a step of preparing the three-dimensional tissue aggregate of the retinal pigment epithelial cells, and a step of subjecting the three-dimensional tissue aggregate of the retinal pigment epithelial cells to a freezing treatment at a predetermined freezing temperature set in advance using, as an index, the occurrence rate of a linear aggregate of dead cells in the three-dimensional tissue aggregate of the retinal pigment epithelial cells after thawing, thus obtaining the frozen body.

Abstract: The invention provides a cell and biotissue transporting container for transporting cells or biotissues while maintaining their cultured state. A cell/biotissue transporting container A10 includes a base member 1 with an opening 110 at an upper end and a first tubular portion 11 extending vertically, a lid body 2 including a top plate portion 21 to close the opening 110 and a second tubular portion 22 extending from a peripheral edge of the top plate portion 21 in the thickness direction to fit onto the first tubular portion 11, and a container body 3, formed separately from the base member 1 using a flexible material, where the container body includes a bottom wall portion 31, a tubular side wall portion 32 rising from a peripheral edge of the bottom wall portion 31 and inserted into the opening 110, and a flange 33 extending outward from an upper edge of the side wall portion 32.

Abstract: The present invention relates to a method for cutting a cell sheet S, which includes cutting the cell sheet S that is cultured in the inside of a container 4 which has accommodated a culture medium M therein, by a cutting device 3 that emits a laser L. The cutting method includes: removing the culture medium M from the container 4 and also sealing the container 4 by a lid portion 13 provided with a transmission part made from a material which allows the laser L to pass through, in the inside of an aseptic room 2 that has been kept in an aseptic condition; taking out the container 4 sealed by the lid portion 13, from the aseptic room 2, and moving the container to the cutting device 3 that is provided in the outside of the aseptic room 2; and in the cutting device 3, passing the laser L through the transmission part of the lid portion 13, and cutting the cell sheet S by the laser L. The method enables the cell sheet S to be cut in such a state that the aseptic condition is kept.

Abstract: An object is to provide a novel medical use of adipose tissue-derived mesenchymal stem cells. It was discovered that adipose tissue-derived mesenchymal stem cells (ASC) promote improvement of erectile dysfunction and recovery of the urge to urinate (improvement of sensory disorders of the lower urinary tract). On the basis of the discovery, a cell preparation containing adipose tissue-derived mesenchymal stem cells, which is effective to erectile dysfunction or sensory disorders of the lower urinary tract, is provided. In one embodiment, adipose tissue-derived mesenchymal stem cells and body fat are used in combination.

Abstract: An object is to provide a novel medical use of adipose tissue-derived mesenchymal stem cells. It was discovered that adipose tissue-derived mesenchymal stem cells (ASC) promote improvement of erectile dysfunction and recovery of the urge to urinate (improvement of sensory disorders of the lower urinary tract). On the basis of the discovery, a cell preparation containing adipose tissue-derived mesenchymal stem cells, which is effective to erectile dysfunction or sensory disorders of the lower urinary tract, is provided. In one embodiment, adipose tissue-derived mesenchymal stem cells and body fat are used in combination.

Abstract: An object is to provide a novel medical use of adipose tissue-derived mesenchymal stem cells. It was discovered that adipose tissue-derived mesenchymal stem cells (ASC) promote improvement of erectile dysfunction and recovery of the urge to urinate (improvement of sensory disorders of the lower urinary tract). On the basis of the discovery, a cell preparation containing adipose tissue-derived mesenchymal stem cells, which is effective to erectile dysfunction or sensory disorders of the lower urinary tract, is provided. In one embodiment, adipose tissue-derived mesenchymal stem cells and body fat are used in combination.