Patents by Inventor Naotaka Hamasaki

Naotaka Hamasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REAGENT FOR MEASURING TOTAL PROTEIN S ACTIVITY
    Publication number: 20160076078
    Abstract: A reagent is used for measuring a total protein S activity in a specimen of a patient to detect protein S abnormality. The reagent includes a first reagent containing at least activated protein C, a first phospholipid, a first surfactant, and calcium ions; a second reagent containing at least activated blood coagulation factor V, the first phospholipid, the first surfactant, and the calcium ions; and a third reagent containing at least activated blood coagulation factor X, prothrombin, a substrate of thrombin, a second phospholipid having a composition different from that of the first phospholipid, and the calcium ions. The first reagent, the second reagent, and the third reagent are prepared separately so that the first reagent, the second reagent, and the third reagent are sequentially applied to the specimen.
    Type: Application
    Filed: November 25, 2015
    Publication date: March 17, 2016
    Inventors: Naotaka HAMASAKI, Tomohide TSUDA, Xiuri JIN
  • Method of detecting colorectal cancer of stages 0 to I
    Patent number: 9134313
    Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: September 15, 2015
    Assignees: Tokyo Metropolitan Organization For Medical Research, CRC Inc., Tokyo Metropolitan Government, Trans Genic Inc.
    Inventors: Masao Kawakita, Kyoko Hiramatsu, Keiichi Takahashi, Naotaka Hamasaki, Koji Yamaguchi, Tsunehisa Kaku, Koichiro Muta, Munechika Enjoji, Seiji Naito, Jun Hayashi, Shoshu Mitsuyama, Hiroyuki Yamashita, Toru Inoue, Masato Kato
  • METHOD FOR DETECTING PROTEIN S ABNORMALITES
    Publication number: 20140057308
    Abstract: A method of detecting protein S abnormalities of the invention includes the steps of: measuring an activity value of total protein S and a protein content of total protein S in a specimen, and comparing between the protein activity of the total protein S and the protein content of total protein S, which are obtained from the measurements.
    Type: Application
    Filed: September 12, 2013
    Publication date: February 27, 2014
    Applicant: School Corporation Kyushu Bunka Gakuen
    Inventors: Naotaka HAMASAKI, Tomohide TSUDA, Xiuri JIN
  • N1, N12-DIACETYLSPERMINE AS TUMOR MARKER
    Publication number: 20090298098
    Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 3, 2009
    Applicants: TOKYO METROPOLITAN ORGANIZATION FOR MEDICAL RESEARCH, CRC Inc., Tokyo Metropolitan Government, Trans Genic Inc.
    Inventors: Masao KAWAKITA, Kyoko HIRAMATSU, Keiichi TAKAHASHI, Naotaka HAMASAKI, Koji YAMAGUCHI, Tsunehisa KAKU, Koichiro MUTA, Munechika ENJOJI, Seiji NAITO, Jun HAYASHI, Shoshu MITSUYAMA, Hiroyuki YAMASHITA, Toru INOUE, Masato KATO
  • N1,n12-diacetylspermine as tumor marker
    Publication number: 20070161059
    Abstract: A tumor marker comprising diacetylspermine, and a method of evaluating the state of a tumor, comprising reacting an antibody to diacetylspermine with a biological sample to thereby detect diacetylspermine and evaluating the state of the tumor using the obtained detection results as an indicator.
    Type: Application
    Filed: March 11, 2004
    Publication date: July 12, 2007
    Applicant: Trans Genic Inc.
    Inventors: Masao Kawakita, Kyoko Hiramatsu, Keiichi Takahashi, Naotaka Hamasaki, Koji Yamaguchi, Tsunehisa Kaku, Koichiro Muta, Munechika Enjoji, Seiji Naito, Jun Hayashi, Shoshu Mitsuyama, Hiroyuki Yamashita, Toru Inoue, Masato Kato
  • Process for preparing monosodium phosphoenolpyruvate
    Patent number: 4874882
    Abstract: Disclosed are a process for preparing monosodium phosphoenolpyruvate, which comprises subjecting monosodium monosubstituted phosphoenolpyruvate of Formula (I): ##STR1## wherein, R represents an alkyl group, a cycloalkyl group or an aralkyl group,to hydrolysis, and a use of monosodium phosphoenolpyruvate as a visceral function improver.This invention provides a simple production process of monosodium phosphoenolpyruvate which is practicable on an industrial acale.
    Type: Grant
    Filed: March 18, 1987
    Date of Patent: October 17, 1989
    Assignee: Ube Industries, Ltd.
    Inventors: Naotaka Hamasaki, Hirotaka Kawamura, Norio Ohtsu, Ichiro Nakakoshi, Kikuo Ataka, Kiyosi Oomori, Masahiko Kouno
  • Additive solution for blood preservation and activation
    Patent number: 4769318
    Abstract: There is disclosed an additive solution for blood preservation and activation, which comprises a phosphoenolpyruvic acid represented by the following formula (I): ##STR1## wherein R.sub.1 represents a hydrogen atom or an alkyl group having 1 to 12 carbon atoms, R.sub.2 and R.sub.3 represent a hydrogen atom, an alkali metal or an alkyl group having 1 to 12 carbon atoms respectively, a saccharide, adenine and an organic acid and/or a pharmaceutically acceptable alkali metal salt of the organic acid.
    Type: Grant
    Filed: April 15, 1987
    Date of Patent: September 6, 1988
    Assignees: Ube Industries, Ltd., The Japanese Red Cross Society
    Inventors: Naotaka Hamasaki, Shigeru Sasakawa, Masayuki Shiba