Patents by Inventor Naoto Kaneko
Naoto Kaneko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10138480Abstract: The present invention provides a novel technique by which the redox activity of a nucleic acid molecule can be evaluated. An evaluation method of the present invention includes: a detection step of electrochemically detecting a redox reaction to a substrate, the redox reaction being catalyzed by a nucleic acid molecule to be evaluated, using a device that electrochemically detects a redox reaction; and an evaluation step of evaluating redox activity of the nucleic acid molecule from a result of the detection of the redox reaction. As the device, a device in which a base provided with a detection portion is included, the detection portion includes an electrode system, and the nucleic acid molecule to be evaluated is arranged on the base is used. In the present invention, it is preferred that a plurality of kinds of nucleic acid molecule to be evaluated is arranged on the base, and the plurality of kinds of nucleic acid molecules to be evaluated is evaluated by a single device.Type: GrantFiled: November 16, 2015Date of Patent: November 27, 2018Assignee: NEC SOLUTION INNOVATORS, LTD.Inventors: Naoto Kaneko, Katsunori Horii, Jou Akitomi, Shintarou Katou, Iwao Waga
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Publication number: 20180327746Abstract: The present invention provides a novel nucleic acid molecule that can be used for detection of ?-amylase. The ?-amylase-binding nucleic acid molecule of the present invention is characterized in that it binds to ?-amylase with a dissociation constant of 17 nM or less, and preferably includes a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 22, for example. According to the nucleic acid molecule of the present invention, it is possible to detect ?-amylase in saliva.Type: ApplicationFiled: September 12, 2016Publication date: November 15, 2018Applicants: NEC Solution Innovators, Ltd., Gunma UniversityInventors: Hirotaka MINAGAWA, Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Ikuo SHIRATORI, Iwao WAGA, Masayasu KUWAHARA
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Publication number: 20180238867Abstract: The present invention provides a new detection device and a target detection method using the same. The detection device of the present invention includes a transistor provided with a nucleic acid sensor. The nucleic acid sensor includes a conformation-forming region (D) that forms a predetermined conformation and a binding region (A) that binds to a target. In the absence of the target, the conformation-forming region (D) is inhibited from forming the conformation. In the presence of the target, upon contact of the target to the binding region (A), the conformation-forming region (D) forms the conformation. In a state where the conformation is formed, the number of nucleotide residues that compose the nucleic acid sensor within a range of Debye length of the transistor increases or decreases as compared to a state where formation of the conformation is inhibited.Type: ApplicationFiled: October 27, 2016Publication date: August 23, 2018Applicant: NEC Solution Innovators, Ltd.Inventors: Katsunori HORII, Naoto KANEKO
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Patent number: 10012631Abstract: The present invention is intended to provide a novel fluorescence sensor for target analysis, a kit for target analysis, and a target analysis method using the same. The fluorescence sensor for target analysis according to the present invention includes a nucleic acid molecule that includes a G-quartet-forming nucleic acid region (D) that forms a G-quartet and a binding nucleic acid region (A) that binds to a target. In the absence of a target, formation of a G-quartet in the G-quartet-forming nucleic acid region (D) is inhibited. In the presence of a target, the target comes into contact with the binding nucleic acid region (A), the G-quartet is formed in the G-quartet-forming nucleic acid region (D) due to the contact, the G-quartet-forming region (D) and porphyrin forms a complex, and the complex generates fluorescence.Type: GrantFiled: June 27, 2014Date of Patent: July 3, 2018Assignee: NEC Solution Innovators, Ltd.Inventors: Naoto Kaneko, Ikuo Shiratori, Katsunori Horii, Jou Akitomi, Iwao Waga
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Patent number: 9880161Abstract: The present invention provides a novel sensor for detecting streptavidin (SA). The nucleic acid sensor for analyzing SA of the present invention includes the following nucleic acid element that includes a catalyst nucleic acid molecule (D) that exerts a catalytic function and a binding nucleic acid molecule (A) that binds to SA. The nucleic acid element is a double-stranded nucleic acid element including a first strand and a second strand. The first strand (ss1) includes the binding nucleic acid molecule (A), a loop-forming sequence (L1), and the catalyst nucleic acid molecule (D) linked in this order. The second strand (ss2) includes a stem-forming sequence (SA), a loop-forming sequence (L2), and a stem-forming sequence (SD) linked in this order.Type: GrantFiled: March 21, 2013Date of Patent: January 30, 2018Assignee: NEC Solution Innovators, Ltd.Inventors: Katsunori Horii, Naoto Kaneko, Jou Akitomi, Shintaro Kato, Iwao Waga
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Patent number: 9880174Abstract: The present invention provides a novel sensor for detecting a target. The nucleic acid sensor of the present invention includes a nucleic acid element that includes a catalyst nucleic acid molecule (D) that exerts a catalytic function and a binding nucleic acid molecule (A) that binds to a target. The nucleic acid element is a double-stranded nucleic acid element including a first strand and a second strand. The first strand (ss1) includes the binding nucleic acid molecule (A), a loop-forming sequence (L1), and the catalyst nucleic acid molecule (D) linked in this order. The second strand (ss2) includes a stem-forming sequence (SA), a loop-forming sequence (L2), and a stem-forming sequence (SD) linked in this order.Type: GrantFiled: December 12, 2012Date of Patent: January 30, 2018Assignee: NEC Solution Innovators, Ltd.Inventors: Katsunori Horii, Naoto Kaneko, Jou Akitomi, Shintarou Katou, Iwao Waga
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Publication number: 20170356905Abstract: A target analysis tool and a target analysis method that allow easily analysis of a target. The first target analysis tool includes: a first chamber; a second chamber; and a third chamber. The first chamber, the second chamber, and the third chamber are disposed continuously in this order. The first chamber contains, as a first reagent, an immobilized first binding substance obtained by immobilizing, on a carrier, a first binding substance that binds to a target. The second chamber contains, as a second reagent, a labeled second binding substance obtained by binding a labeling substance to a second binding substance that binds to the first binding substance. The third chamber is a detection section in which the labeled second binding substance is detected.Type: ApplicationFiled: January 22, 2016Publication date: December 14, 2017Applicant: NEC Solution Innovators, Ltd.Inventors: Iwao WAGA, Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Yoshihito YOSHIDA
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Patent number: 9797888Abstract: The present invention provides a novel nucleic acid element candidate molecule for use in screening for a nucleic acid element for target analysis and a novel screening method for screening for a nucleic acid element for target analysis using the same. The candidate molecule according to the present invention is a molecule for screening for a nucleic acid element for target analysis, being the following single-stranded nucleic acid (I): (I) a single-stranded nucleic acid comprising a catalyst sequence (D), a blocking sequence (B), and a binding sequence (A) that binds to a target, linked in this order. The blocking sequence (B) is complementary to a partial region (Dp) in the catalyst sequence (D). A terminal region (Ab) on the blocking sequence (B) side in the binding sequence (A) is complementary to a flanking region (Df) of the partial region (Dp) in the catalyst sequence (D) and is complementary to a terminal region (Af) on the side opposite to the blocking sequence (B) side in the binding sequence (A).Type: GrantFiled: February 17, 2014Date of Patent: October 24, 2017Assignee: NEC Solution Innovators, Ltd.Inventors: Jou Akitomi, Naoto Kaneko, Katsunori Horii
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Patent number: 9790508Abstract: The present invention provides a novel nucleic acid molecule that can be used for detection of peanuts. The peanut-binding nucleic acid molecule of the present invention is characterized in that it binds to a peanut allergen with a dissociation constant of 10 nM or less, and preferably contains a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 15, for example. It is also preferable that, for example, the peanut-binding nucleic acid molecule of the present invention binds with significant specificity to the peanut allergen rather than to a soybean protein.Type: GrantFiled: June 26, 2014Date of Patent: October 17, 2017Assignee: NEC Solution Innovators, Ltd.Inventors: Tomoko Murata, Katsunori Horii, Ikuo Shiratori, Jou Akitomi, Naoto Kaneko, Iwao Waga
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Patent number: 9783807Abstract: A nucleic acid molecule utilizable for Salmonella detection is provided. The nucleic acid molecule which binds to Salmonella includes any of the following polynucleotides (a) to (d): (a) a polynucleotide composed of any of base sequences of SEQ ID NOs: 1 to 17; (b) a polynucleotide composed of a base sequence obtained by deletion, substitution, insertion, and/or addition of one or more bases in any of the base sequences in the polynucleotide (a) and is bound to Salmonella; (c) a polynucleotide composed of a base sequence having an identity of 80% or more to any of the base sequences in the polynucleotide (a) and is bound to Salmonella; and (d) a polynucleotide composed of a base sequence complementary to a polynucleotide which hybridizes to the polynucleotide (a) composed of any of the base sequences under stringent conditions and is bound to Salmonella.Type: GrantFiled: November 6, 2013Date of Patent: October 10, 2017Assignee: NEC SOLUTION INNOVATORS, LTD.Inventors: Hirotaka Minagawa, Jou Akitomi, Naoto Kaneko, Makio Furuichi, Katsunori Horii, Iwao Waga
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Patent number: 9637737Abstract: The present invention provides a novel technique by which the redox activity of a nucleic acid molecule can be evaluated. An evaluation method of the present invention includes: a detection step of electrochemically detecting a redox reaction to a substrate, the redox reaction being catalyzed by a nucleic acid molecule to be evaluated, using a device that electrochemically detects a redox reaction; and an evaluation step of evaluating redox activity of the nucleic acid molecule from a result of the detection of the redox reaction. As the device, a device in which a base provided with a detection portion is included, the detection portion includes an electrode system, and the nucleic acid molecule to be evaluated is arranged on the base is used. In the present invention, it is preferred that a plurality of kinds of nucleic acid molecule to be evaluated is arranged on the base, and the plurality of kinds of nucleic acid molecules to be evaluated is evaluated by a single device.Type: GrantFiled: July 2, 2012Date of Patent: May 2, 2017Assignee: NEC SOLUTION INNOVATORS, LTD.Inventors: Naoto Kaneko, Katsunori Horii, Jou Akitomi, Shintarou Katou, Iwao Waga
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Publication number: 20160298117Abstract: The present invention provides a novel nucleic acid molecule that can be used for detection of peanuts. The peanut-binding nucleic acid molecule of the present invention is characterized in that it binds to a peanut allergen with a dissociation constant of 10 nM or less, and preferably contains a polynucleotide consisting of any of base sequences of SEQ ID NOs: 1 to 15, for example. It is also preferable that, for example, the peanut-binding nucleic acid molecule of the present invention binds with significant specificity to the peanut allergen rather than to a soybean protein.Type: ApplicationFiled: June 26, 2014Publication date: October 13, 2016Applicant: NEC Solution Innovators, Ltd.Inventors: Tomoko MURATA, Katsunori HORII, Ikuo SHIRATORI, Jou AKITOMI, Naoto KANEKO, Iwao WAGA
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Patent number: 9410815Abstract: An entry point card displayed within a mapping application viewport may display context and other data based on a calendar appointment and other data that the user might, predictably, want to search for upon opening the mapping application. Using appointment information from a calendar application, an entry point card might display a time the user must leave his current location in order to make the appointment on time. Or, using a history of the user's routine errands or trips, the entry point card may display predicted information. For example, the card may display an amount of time to get to work or other information.Type: GrantFiled: March 20, 2015Date of Patent: August 9, 2016Assignee: GOOGLE INC.Inventors: Takahito Hirano, Ryo Kawaguchi, Masanori Goto, Koichi Suematsu, Pawel Szczepanski, Takahiro Kosakai, Naoto Kaneko, Taj J. Campbell, Peter Foo, Kaori Kozai
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Publication number: 20160202154Abstract: The present invention is intended to provide a novel sensor for target analysis and a target analysis method using the same. The sensor for target analysis according to the present invention includes a single-stranded nucleic acid molecule. The single-stranded nucleic acid molecule includes a first catalytic nucleic acid region (D1), a second catalytic nucleic acid region (D2), and a binding nucleic acid region (Ap) that binds to a target. The single-stranded nucleic acid molecule includes the first catalytic nucleic acid region (D1) at one end of the binding nucleic acid region (Ap) and the second catalytic nucleic acid region (D2) at the other end of the binding nucleic acid (Ap). In the absence of a target, the catalytic function by the first catalytic nucleic acid region (D1) and the second catalytic nucleic acid region (D2) is inhibited.Type: ApplicationFiled: June 27, 2014Publication date: July 14, 2016Applicant: NEC Solution Innovators, Ltd.Inventors: Katsunori HORII, Jou AKITOMI, Naoto KANEKO, Iwao WAGA
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Publication number: 20160169875Abstract: The present invention is to provide a new sensor for melamine detection. The nucleic acid sensor for melamine analysis of the present invention includes a polynucleotide (x1) that includes a catalytic nucleic acid molecule (D) that activates a catalytic function and a binding nucleic acid molecule (A) that binds to melamine. The polynucleotide (x1) has any one of the base sequences of SEQ ID NOs: 1 to 14, and n and m are positive integers. In the nucleic acid sensor, since the catalytic function of the catalytic nucleic acid molecule (D) is inhibited in the absence of melamine and the catalytic function of the catalytic nucleic acid molecule (D) is activated in the presence of melamine, melamine can be analyzed by detecting the catalytic function.Type: ApplicationFiled: July 23, 2013Publication date: June 16, 2016Inventors: Katsunori Horii, Naoto Kaneko, Jou Akitomi, Shintarou Katou, Makio Furuichi, Iwao Waga
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Publication number: 20160146772Abstract: The present invention is intended to provide a novel fluorescence sensor for target analysis, a kit for target analysis, and a target analysis method using the same. The fluorescence sensor for target analysis according to the present invention includes a nucleic acid molecule that includes a G-quartet-forming nucleic acid region (D) that forms a G-quartet and a binding nucleic acid region (A) that binds to a target. In the absence of a target, formation of a G-quartet in the G-quartet-forming nucleic acid region (D) is inhibited. In the presence of a target, the target comes into contact with the binding nucleic acid region (A), the G-quartet is formed in the G-quartet-forming nucleic acid region (D) due to the contact, the G-quartet-forming region (D) and porphyrin forms a complex, and the complex generates fluorescence.Type: ApplicationFiled: June 27, 2014Publication date: May 26, 2016Applicant: NEC Solution Innovators, Ltd.Inventors: Naoto KANEKO, Ikuo SHIRATORI, Katsunori HORII, Jou AKITOMI, Iwao WAGA
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Publication number: 20160060630Abstract: The present invention provides a novel technique by which the redox activity of a nucleic acid molecule can be evaluated. An evaluation method of the present invention includes: a detection step of electrochemically detecting a redox reaction to a substrate, the redox reaction being catalyzed by a nucleic acid molecule to be evaluated, using a device that electrochemically detects a redox reaction; and an evaluation step of evaluating redox activity of the nucleic acid molecule from a result of the detection of the redox reaction. As the device, a device in which a base provided with a detection portion is included, the detection portion includes an electrode system, and the nucleic acid molecule to be evaluated is arranged on the base is used. In the present invention, it is preferred that a plurality of kinds of nucleic acid molecule to be evaluated is arranged on the base, and the plurality of kinds of nucleic acid molecules to be evaluated is evaluated by a single device.Type: ApplicationFiled: November 16, 2015Publication date: March 3, 2016Inventors: Naoto KANEKO, Katsunori Horii, Jou Akitomi, Shintarou Katou, Iwao Waga
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Publication number: 20160040023Abstract: For transparent electrodes formed by using a metal nanowire-based transparent conductive film, accomplished are simplification of processes necessary in patterning the transparent conductive film and improvement in patterning accuracy of the transparent electrodes formed by using the transparent conductive film. An ink for forming the transparent conductive film used for the transparent electrodes having a distance between the electrodes of 20 ?m or more contains: metal nanowires, a photosensitive material; and a solvent. The metal nanowires have an average length of 1.5 times or less the distance between the electrodes.Type: ApplicationFiled: April 2, 2014Publication date: February 11, 2016Applicant: Dexerials CorporationInventors: Yasuhisa ISHII, Mikihisa MIZUNO, Junichi INOUE, Naoto KANEKO
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Publication number: 20160003811Abstract: The present invention provides a novel nucleic acid element candidate molecule for use in screening for a nucleic acid element for target analysis and a novel screening method for screening for a nucleic acid element for target analysis using the same. The candidate molecule according to the present invention is a molecule for screening for a nucleic acid element for target analysis, being the following single-stranded nucleic acid (I): (I) a single-stranded nucleic acid comprising a catalyst sequence (D), a blocking sequence (B), and a binding sequence (A) that binds to a target, linked in this order. The blocking sequence (B) is complementary to a partial region (Dp) in the catalyst sequence (D). A terminal region (Ab) on the blocking sequence (B) side in the binding sequence (A) is complementary to a flanking region (Df) of the partial region (Dp) in the catalyst sequence (D) and is complementary to a terminal region (Af) on the side opposite to the blocking sequence (B) side in the binding sequence (A).Type: ApplicationFiled: February 17, 2014Publication date: January 7, 2016Applicant: NEC SOLUTION INNOVATORS, LTD.Inventors: Jou AKITOMI, Naoto KANEKO, Katsunori HORII
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Publication number: 20150299709Abstract: A nucleic acid molecule utilizable for Salmonella detection is provided. The nucleic acid molecule which binds to Salmonella includes any of the following polynucleotides (a) to (d): (a) a polynucleotide composed of any of base sequences of SEQ ID NOs: 1 to 17; (b) a polynucleotide composed of a base sequence obtained by deletion, substitution, insertion, and/or addition of one or more bases in any of the base sequences in the polynucleotide (a) and is bound to Salmonella; (c) a polynucleotide composed of a base sequence having an identity of 80% or more to any of the base sequences in the polynucleotide (a) and is bound to Salmonella; and (d) a polynucleotide composed of a base sequence complementary to a polynucleotide which hybridizes to the polynucleotide (a) composed of any of the base sequences under stringent conditions and is bound to Salmonella.Type: ApplicationFiled: November 6, 2013Publication date: October 22, 2015Inventors: Hirotaka Minagawa, Jou Akitomi, Naoto Kaneko, Makio Furuichi, Katsunori Horii, lwao Waga