Patents by Inventor Naoto Mamiya

Naoto Mamiya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HCV core protein binding agents for treatment of hepatitis C virus infection
    Patent number: 7094401
    Abstract: The present invention provides a method of treating or preventing hepatitis C virus infection in a subject which comprises administering an effective amount of an agent to the subject, wherein the agent is capable of specifically binding to the HCV core protein so as to inhibit hepatitis C virus replication. The present invention also provides a method for determining whether a compound can treat or prevent hepatitis C virus infection in a subject, wherein the compound treats or prevents hepatitis C virus infection by specifically inhibiting the binding of HCV core protein and said agent so as to suppress hepatitis C virus replication. The present invention further provides a composition for inhibiting cell growth, comprises a HCV core protein or a variant thereof, wherein said HCV core protein or its variant inhibit cancer cell growth by inhibiting the cellular DEAD box proteins.
    Type: Grant
    Filed: September 29, 1999
    Date of Patent: August 22, 2006
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Howard J. Worman, Naoto Mamiya
  • HCV E2 PROTEIN BINDING AGENTS FOR TREATMENT OF HEPATITIS C VIRUS INFECTION
    Publication number: 20020160936
    Abstract: The present invention provides a method of treating or preventing hepatitis C virus infection in a subject which comprises administering an effective amount of an agent to the subject, wherein the agent is capable of inhibiting the attachment of hepatitis C virus onto cells by specifically binding to the hepatitis C virus envelope E2 protein so as to treat or prevent hepatitis C virus infection.
    Type: Application
    Filed: September 29, 1999
    Publication date: October 31, 2002
    Inventors: HOWARD J. WORMAN, NAOTO MAMIYA