Patents by Inventor Naoto Matsuishi

Naoto Matsuishi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetrazolyl-substituted pyrido[1,2-a]pyrimidines and use as SRS-A antagonists
    Patent number: 4816459
    Abstract: Pyrido[1,2-a]pyrimidine derivatives of the general formula [I] and their physiologically acceptable salts are provided: ##STR1## where R is a hydrogen atom, a halogen atom or a methyl group, and n is a whole number of 0, 1 or 2. The pyrido[1,2-a]-pyrimidine derivatives and their salts exhibit an excellent antagonistic effect on slow-reacting substance of anaphylaxis and, therefore, are useable for the treatment of allergic diseases.
    Type: Grant
    Filed: October 1, 1986
    Date of Patent: March 28, 1989
    Assignee: Tokyo Tanabe Co. Ltd.
    Inventors: Naoto Matsuishi, Yoshio Nakagawa, Michiaki Amano, Norihiko Kakehi, Toshio Kawashima, Shigeki Omura
  • Imidazo[4,5-b]pyridine compounds and pharmaceutical compositions containing same
    Patent number: 4808596
    Abstract: Imidazo[4,5-b]pyridine compounds of the general formula [I] are provided: ##STR1## where R.sup.1 is straight-chain or branched C.sub.1-8 alkoxy which may be substituted with cycloalkyl, or C.sub.2-4 fluoroalkyloxy, R.sup.2 is H, methyl or methoxy, and R.sup.3 and R.sup.4 are each H or methyl and may be the same or different. All these compounds have good activity of inhibiting potassium ion-dependent adenosine triphosphatase and excellent storage stability, so that they are usable for the treatment of gastric and/or duodenal ulcers.
    Type: Grant
    Filed: July 24, 1987
    Date of Patent: February 28, 1989
    Assignee: Tokyo Tanabe Company, Ltd.
    Inventors: Naoto Matsuishi, Haruki Takeda, Kenichi Iizumi, Kiyokazu Murakami, Akira Hisamitsu
  • Pyrido[1,2-a]pyrimidine compounds, corresponding intermediates and use as SRS-A antagonists
    Patent number: 4798832
    Abstract: Pyrido[1,2-a]pyrimidine derivatives of the general formula [I] and their physiologically acceptable salts are provided: ##STR1## where R is a hydrogen atom, a halogen atom or a methyl group, and n is 0, 1 or 2. The pyrido[1,2-a]pyrimidine derivatives and their salts exhibit an excellent antagonistic effect on slow-reacting substance of anaphylaxis and, therefore, are useable for the treatment of allergic diseases.
    Type: Grant
    Filed: April 13, 1987
    Date of Patent: January 17, 1989
    Assignee: Tokyo Tanabe Company, Limited
    Inventors: Naoto Matsuishi, Yoshio Nakagawa, Michiaki Amano, Norihiko Kakehi, Toshio Kawashima, Shigeki Omura
  • Benzimidazole derivatives
    Patent number: 4753955
    Abstract: Benzimidazole derivatives of the general formula [I] are provided: ##STR1## wherein R.sup.1 is hydrogen, methyl or methoxy, and R.sup.2 and R.sup.3 each is hydrogen or methyl, at least one of R.sup.1, R.sup.2 and R.sup.3 being a member other than hydrogen. The benzimidazole derivatives exhibit an excellent activity of inhibiting the potassium ion-dependent adenosine triphosphatase, as well as a good stability during storage. Therefore, the benzimidazole derivatives are usable for the treatment of gastric and/or duodenal ulcers.
    Type: Grant
    Filed: February 10, 1987
    Date of Patent: June 28, 1988
    Assignee: Tokyo Tanabe Company, Ltd.
    Inventors: Naoto Matsuishi, Haruki Takeda, Kenichi Iizumi, Kiyokazu Murakami, Akira Hisamitsu