Patents by Inventor Naotoshi Tomita
Naotoshi Tomita has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11660383Abstract: An object of the present invention is to provide a material which can remove an activated leukocyte-activated platelet complex with high efficiency. The present invention provides a material for removing an activated leukocyte-activated platelet complex, the material being a water-insoluble carrier to the surface of which carrier a compound(s) having a charged functional group(s) is(are) bound, wherein an extending length ratio of the surface is 4 to 7.Type: GrantFiled: December 7, 2020Date of Patent: May 30, 2023Assignee: TORAY INDUSTRIES, INC.Inventors: Naotoshi Tomita, Kaoru Shimada, Hiroshi Takahashi
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Publication number: 20210086166Abstract: An object of the present invention is to provide a material which can remove an activated leukocyte-activated platelet complex with high efficiency. The present invention provides a material for removing an activated leukocyte-activated platelet complex, the material being a water-insoluble carrier to the surface of which carrier a compound(s) having a charged functional group(s) is(are) bound, wherein an extending length ratio of the surface is 4 to 7.Type: ApplicationFiled: December 7, 2020Publication date: March 25, 2021Applicant: TORAY INDUSTRIES, INC.Inventors: Naotoshi TOMITA, Kaoru SHIMADA, Hiroshi TAKAHASHI
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Patent number: 10888840Abstract: An object of the present invention is to provide a material which can remove an activated leukocyte-activated platelet complex with high efficiency. The present invention provides a material for removing an activated leukocyte-activated platelet complex, the material being a water-insoluble carrier to the surface of which carrier a compound(s) having a charged functional group(s) is(are) bound, wherein an extending length ratio of the surface is 4 to 7.Type: GrantFiled: June 6, 2018Date of Patent: January 12, 2021Assignee: TORAY INDUSTRIES, INC.Inventors: Naotoshi Tomita, Kaoru Shimada, Hiroshi Takahashi
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Publication number: 20200197594Abstract: An object of the present invention is to provide a material which can remove an activated leukocyte-activated platelet complex with high efficiency. The present invention provides a material for removing an activated leukocyte-activated platelet complex, the material being a water-insoluble carrier to the surface of which carrier a compound(s) having a charged functional group(s) is(are) bound, wherein an extending length ratio of the surface is 4 to 7.Type: ApplicationFiled: June 6, 2018Publication date: June 25, 2020Applicant: TORAY INDUSTRIES, INC.Inventors: Naotoshi TOMITA, Kaoru SHIMADA, Hiroshi TAKAHASHI
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Patent number: 10646850Abstract: An object of the present invention is to provide a material for blood purification having the capability to remove cytokines and activated leukocyte-activated platelet complexes. The present invention provides a material for blood purification, the material containing a water-insoluble material in which a ligand having an amide group(s) and an amino group(s) is bound to a substrate, wherein the content of the amide group(s) is 3.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material; and wherein the content of the amino group(s) is 1.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material.Type: GrantFiled: September 8, 2017Date of Patent: May 12, 2020Assignee: TORAY INDUSTRIES, INC.Inventors: Shungo Kanda, Hiroshi Takahashi, Naotoshi Tomita
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Publication number: 20190184371Abstract: An object of the present invention is to provide a material for blood purification having the capability to remove cytokines and activated leukocyte-activated platelet complexes. The present invention provides a material for blood purification, the material containing a water-insoluble material in which a ligand having an amide group(s) and an amino group(s) is bound to a substrate, wherein the content of the amide group(s) is 3.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material; and wherein the content of the amino group(s) is 1.0 to 7.0 mmol per 1 g dry weight of the water-insoluble material.Type: ApplicationFiled: September 8, 2017Publication date: June 20, 2019Applicant: TORAY INDUSTRIES, INC.Inventors: Shungo KANDA, Hiroshi TAKAHASHI, Naotoshi TOMITA
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Patent number: 9982369Abstract: A fiber for protein adsorption has a water absorption percentage of 1 to 50%, and the fiber includes a polymer containing as repeat units an aromatic hydrocarbon or a derivative thereof, wherein part of aromatic rings contained in the repeat units are cross-linked through a structure represented by Formula (I). A column for protein adsorption uses the fibers. A in Formula (I) is selected from an alkyl aliphatic group, phenyl aromatic group and amino group.Type: GrantFiled: September 16, 2015Date of Patent: May 29, 2018Assignee: Toray Industries, Inc.Inventors: Junichi Kasuya, Naotoshi Tomita, Yoshiyuki Ueno
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Patent number: 9937440Abstract: An adsorption carrier-packed column includes a central pipe, adsorption carrier, plate A, and plate B, wherein an insertion material C is inserted between the adsorption carrier and the plate A; an insertion material D is inserted between the adsorption carrier and the plate B; the ratio of the deformation rate of the insertion material C (C1) to the deformation rate of the adsorption carrier (E0) is 1<C1/E0<10, and the ratio of the deformation rate of the insertion material D (D1) to the deformation rate of the adsorption carrier (E0) is 1<D1/E0<10; and the ratio of the thickness of the insertion material C (TC) to the distance of a gap between the adsorption carrier and the plate A (LA) is 1.1<TC/LA<4, and the ratio of the thickness of the insertion material D (TD) to the distance of a gap between the adsorption carrier and the plate B (LB) is 1.1<TD/LB<4.Type: GrantFiled: May 30, 2014Date of Patent: April 10, 2018Assignee: Toray Industries, Inc.Inventors: Naotoshi Tomita, Kaoru Shimada, Yoshiyuki Ueno
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Patent number: 9867927Abstract: A carrier for blood component adsorption enables selective and efficient adsorption removal of granulocytes and monocytes and, at the same time, enables adsorption removal of inflammatory cytokines. The carrier for blood component adsorption includes a water-insoluble carrier having a surface to which a functional group(s) containing a silyl group and an amino group is/are introduced.Type: GrantFiled: February 24, 2012Date of Patent: January 16, 2018Assignee: Toray Industries, Inc.Inventors: Naotoshi Tomita, Yoshiyuki Ueno, Kazuhiro Tanahashi
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Patent number: 9802178Abstract: A carrier for blood component adsorption includes a water-insoluble carrier composed of a fiber or particle, the water-insoluble carrier having a surface to which a functional group(s) is/are introduced, the functional group(s) containing an acidic functional group selected from the group consisting of the sulfate group, sulfite group and sulfonate group; and containing an amino group; the fiber having a fiber diameter of, or the particle having a particle diameter of, 0.5 to 20 ?m.Type: GrantFiled: October 26, 2011Date of Patent: October 31, 2017Assignee: Toray Industries, Inc.Inventors: Naotoshi Tomita, Yoshiyuki Ueno, Kazuhiro Tanahashi
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Publication number: 20170253999Abstract: A fiber for protein adsorption has a water absorption percentage of 1 to 50%, and the fiber includes a polymer containing as repeat units an aromatic hydrocarbon or a derivative thereof, wherein part of aromatic rings contained in the repeat units are cross-linked through a structure represented by Formula (I). A column for protein adsorption uses the fibers. A in Formula (I) is selected from an alkyl aliphatic group, phenyl aromatic group and amino group.Type: ApplicationFiled: September 16, 2015Publication date: September 7, 2017Applicant: Toray Industries, Inc.Inventors: Junichi Kasuya, Naotoshi Tomita, Yoshiyuki Ueno
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Publication number: 20160107100Abstract: An adsorption carrier-packed column includes a central pipe, adsorption carrier, plate A, and plate B, wherein an insertion material C is inserted between the adsorption carrier and the plate A; an insertion material D is inserted between the adsorption carrier and the plate B; the ratio of the deformation rate of the insertion material C (C1) to the deformation rate of the adsorption carrier (E0) is 1<C1/E0<10, and the ratio of the deformation rate of the insertion material D (D1) to the deformation rate of the adsorption carrier (E0) is 1<D1/E0<10; and the ratio of the thickness of the insertion material C (TC) to the distance of a gap between the adsorption carrier and the plate A (LA) is 1.1<TC/LA<4, and the ratio of the thickness of the insertion material D (TD) to the distance of a gap between the adsorption carrier and the plate B (LB) is 1.1<TD/LB<4.Type: ApplicationFiled: May 30, 2014Publication date: April 21, 2016Inventors: Naotoshi Tomita, Kaoru Shimada, Yoshiyuki Ueno
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Patent number: 9023947Abstract: An adsorptive carrier includes one or more high-molecular-weight compounds each of which includes two or more aromatic ring-containing repeating units, the aromatic rings being covalently bound to each other via a structure represented by Formula (I): wherein R1 represents hydrogen or an organic group, and R2 represents an organic group.Type: GrantFiled: August 8, 2012Date of Patent: May 5, 2015Assignee: Toray Industries, Inc.Inventors: Naotoshi Tomita, Yoshiyuki Ueno
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Publication number: 20140206818Abstract: An adsorptive carrier includes one or more high-molecular-weight compounds each of which includes two or more aromatic ring-containing repeating units, the aromatic rings being covalently bound to each other via a structure represented by Formula (I): wherein R1 represents hydrogen or an organic group, and R2 represents an organic group.Type: ApplicationFiled: August 8, 2012Publication date: July 24, 2014Applicant: TORAY INDUSTRIES, INC.Inventors: Naotoshi Tomita, Yoshiyuki Ueno
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Publication number: 20130327698Abstract: A carrier for blood component adsorption enables selective and efficient adsorption removal of granulocytes and monocytes and, at the same time, enables adsorption removal of inflammatory cytokines. The carrier for blood component adsorption includes a water-insoluble carrier having a surface to which a functional group(s) containing a silyl group and an amino group is/are introduced.Type: ApplicationFiled: February 24, 2012Publication date: December 12, 2013Applicant: Toray Industries, Inc.Inventors: Naotoshi Tomita, Yoshiyuki Ueno, Kazuhiro Tanahashi
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Publication number: 20130220912Abstract: A carrier for blood component adsorption includes a water-insoluble carrier composed of a fiber or particle, the water-insoluble carrier having a surface to which a functional group(s) is/are introduced, the functional group(s) containing an acidic functional group selected from the group consisting of the sulfate group, sulfite group and sulfonate group; and containing an amino group; the fiber having a fiber diameter of, or the particle having a particle diameter of, 0.5 to 20 ?m.Type: ApplicationFiled: October 26, 2011Publication date: August 29, 2013Applicant: Toray Industries, Inc.Inventors: Naotoshi Tomita, Yoshiyuki Ueno, Kazuhiro Tanahashi