Abstract: A display selection button 10 comprises a light projecting unit 21, a light guide plate 13, a light receiving units 22, a control unit 30, and LED 23,24. The light guide plate 13 has an incident surface 13a to which the light emitted from the light projecting unit 21 is incident, a plurality of prisms 13d that reflect incident light toward the side approaching or touching a finger and are provided at positions corresponding to push buttons 10c, and an exit surface 13b that emits the light reflected in the direction in which the finger approaches. The light receiving units 22 receive light emitted from the exit surface 13b and reflected from a finger. The control unit 30 detects the approach of a finger depending on the amount of light received by the light receiving units 22. The light guide plate 13 has the plurality of the prisms 13e that reflect the incident light and displays the desired design.

Abstract: A display selection button 10 comprises a light projecting unit 21, a light guide plate 13, a plurality of light receiving units 22, and a control unit 30. The light guide plate 13 has an incident surface 13a, a plurality of prisms 13d that reflect incident light toward the side approached by a finger and are provided at positions corresponding to push buttons 10c, and an exit surface 13b that emits the light reflected by the prisms 13d in the direction in which the finger approaches or touches. The light receiving units 22 are provided at positions corresponding to the push buttons 10c and receive light reflected from a finger approaching a push button 10c. The prisms 13d reflect light so as to compensate for the amount of light that decreases depending on the distance from the light projecting unit 21.

Abstract: A display selection button 10 comprises a light projecting unit 21, a light guide plate 13, a light receiving units 22, a control unit 30, and a printed sheet 14 and a LED 25. The light guide plate 13 has an incident surface 13a to which the light emitted from the light projecting unit 21 is incident, a plurality of prisms 13d that reflect incident light toward the side approaching or touching a finger and are provided at positions corresponding to push buttons 10c, and an exit surface 13b that emits the light reflected in the direction in which the finger approaches. The light receiving units 22 receive light emitted from the exit surface 13b and reflected from a finger. The control unit 30 detects the approach of a finger depending on the amount of light received by the light receiving units 22. The printed sheet 14 displays the desired numerals. The LED 25 emits light for displaying the desired numerals in the printed sheet 14.

Abstract: A display selection button 10 comprises a light projecting unit 21, a light guide plate 13, a plurality of light receiving units 22, and a control unit 30. The light guide plate 13 has an incident surface 13a to which the light projected from the light projecting unit 21 incident, a plurality of prisms 13d that reflect incident light toward the finger side and are provided at positions corresponding to push buttons 10c, and an exit surface 13b that emits the light reflected in the direction in which the finger approaches. The light receiving units 22 are provided at positions corresponding to the push buttons 10c and receive light reflected from a finger. The light receiving unit 22 have higher detection sensitivity as a distance from the light projecting unit 21 increases so as to compensate for the amount of light that decreases depending on the distance from the light projecting unit 21.

Abstract: For example, in agricultural and horticultural crop production, pests, etc. still cause heavy damage, and there is a demand for the development of novel agricultural and horticultural insecticidal agents due to factors such as the emergence of pests resistant to existing drugs. The present invention has found that a compound represented by the general formula (1): wherein X and Y each represent an oxygen atom or a sulfur atom, Z represents a hydroxyl group or the like, R1 represents an alkoxycarbonyl group or the like, R2 represents a substituted phenyl group or the like, R3 represents a hydrogen atom or the like, and R4 represents a substituted phenyl group or the like, or a salt thereof exhibits a high insecticidal effect on pests, etc. in the agricultural and horticultural field, and provides an agricultural and horticultural insecticidal agent comprising the same as an active ingredient and a method for using the same.

Abstract: In production of crops of agriculture and horticulture or the like, damage caused by diseases is still large, and, due to factors such as occurrence of resistant diseases to existing drugs, development of new agrohorticultural fungicides is desired. The present invention provides an agrohorticultural fungicide and a method of use thereof, an active ingredient thereof being a compound represented by the general formula (I) or salts thereof: {wherein R1 denotes a hydrogen atom or (C1-C6)alkyl group or the like. R2 denotes a hydrogen atom or the like. R3 denotes a hydrogen atom or (C1-C6)alkyl group or the like. R4 denotes a (C1-C6)alkyl group, (C3-C6)cycloalkyl group or aryl group or the like. X1 and X2 denote a hydrogen atom or halogen atom or the like. Y denotes an oxygen atom.}.

Abstract: It is intended to reveal a polynucleotide serving as a novel causative gene of a cancer and, on the basis of this finding, to provide a method for detecting the polynucleotide or a polypeptide encoded thereby, a kit and a primer set for the detection, a method for screening for a substance that inhibits the polypeptide, and a pharmaceutical composition for the treatment of a cancer, containing the inhibiting substance. The detection method of the present invention detects a BRAF fusion protein or a fusion gene encoding the fusion protein, or a PXN or GMDS fusion protein or a fusion gene encoding the fusion protein in a digestive organ-derived sample obtained from a subject.

Abstract: A thermal device according to the present disclosure includes a ceramic container, a fluid, and a sealing portion. The container includes an internal space, an opening portion connected to the internal space, and a communication path configured to connect the internal space and the opening portion. The fluid is located in the internal space. The sealing portion blocks the opening portion. The sealing portion includes a core portion and a flange connected to the core portion. The flange is bonded to the container around the opening portion. The core portion is located inside the opening portion. A portion of the core portion is in contact with the wall surface of the opening portion.

Abstract: A semiconductive ceramic member according to the present disclosure contains a plurality of aluminum oxide crystal grains, and a plurality of titanium oxide crystal grains. The total content of aluminum oxide and titanium oxide is 99% by mass or more per 100% by mass of all constituents. The content of the aluminum oxide is 86% by mass or more and 96% by mass or less and the content of the titanium oxide is 4% by mass or more and 14% by mass or less per 100% by mass of the aluminum oxide and the titanium oxide in total. A peak of TiOx (0<x<2) is present within a binding energy range of 456 eV to 462 eV (both inclusive) in X-ray photoelectron spectroscopy measurement. The semiconductive ceramic member further contains silicon, and the content of the silicon in terms of its oxide in a first region is larger than the content of the silicon in terms of its oxide in a grain boundary.

Abstract: In production of crops of agriculture and horticulture or the like, damage caused by diseases is still large, and, due to factors such as occurrence of resistant diseases to existing drugs, development of new agrohorticultural fungicides is desired. The present invention provides an agrohorticultural fungicide and a method of use thereof of, an active ingredient thereof being a compound represented by the general formula (I) or salts thereof: {wherein X1, X2, X3 and X4 denote a hydrogen atom or the like, A, B, Y, denote a single bond or carbonyl group or the like, Q denotes a (C1-C6)alkyl group or hetero ring or the like, R5 and R6 denote a hydrogen atom or (C1-C6)alkyl group or the like.}.

Abstract: A thermal device according to the present disclosure includes a ceramic container, a fluid, and a sealing portion. The container includes an internal space, an opening portion connected to the internal space, and a communication path configured to connect the internal space and the opening portion. The fluid is located in the internal space. The sealing portion blocks the opening portion. The sealing portion includes a core portion and a flange connected to the core portion. The flange is bonded to the container around the opening portion. The core portion is located inside the opening portion. A portion of the core portion is in contact with the wall surface of the opening portion.

Abstract: Described is a method for differentiating destructive thyroiditis, including measuring at least one of monoiodotyrosine and diiodotyrosine in a sample.

Abstract: An X-ray diagnosis apparatus according to the present embodiment comprises: an X-ray irradiator configured to irradiate X-rays; an imager configured to image an identifier that identifies a position of an X-ray detector which detects X-rays; and processing circuitry configured to calculate, based on the identifier shown on an image imaged by the imager, a relative position of the X-ray irradiator regarding the X-ray detector and an irradiation position of the X-ray irradiator where a corresponding relative position meets a predetermined X-ray imaging condition; and output, based on the relative position and the irradiation position, a movement information of the X-ray irradiator.

Abstract: An x-ray diagnostic apparatus according to an embodiment includes a radiographic unit, a movable unit, and processing circuitry. The radiographic unit performs radiography. The movable unit is provided in the radiographic unit and is movable to plural positions. The processing circuitry moves the movable unit to a position where the movable unit and a disinfection apparatus that performs disinfection have a predetermined positional relation to each other.

Abstract: In production of crops of agriculture and horticulture or the like, damage caused by diseases is still large, and, due to factors such as occurrence of resistant diseases to existing drugs, development of new agrohorticultural fungicides is desired. The present invention provides an agrohorticultural fungicide and a method of use thereof of, an active ingredient thereof being a compound represented by the general formula (I) or salts thereof: {wherein X1, X2, X3 and X4 denote a hydrogen atom or the like, A, B, Y, denote a single bond or carbonyl group or the like, Q denotes a (C1-C6)alkyl group or hetero ring or the like, R5 and R6 denote a hydrogen atom or (C1-C6)alkyl group or the like.}.

Abstract: The object of the present invention is to provide a humanized or mouse-human chimeric anti-podoplanin antibody or an antibody fragment containing the antigen-binding region thereof, and the object is achieved by providing an isolated humanized or mouse-human chimeric anti-podoplanin antibody which comprises a predetermined amino acid sequence, or an antibody fragment containing the antigen-binding region thereof.

Abstract: In production of crops of agriculture and horticulture or the like, damage caused by diseases is still large, and, due to factors such as occurrence of resistant diseases to existing drugs, development of new agrohorticultural fungicides is desired. General formula (I) As a result of intensive research to develop novel fungicides, the present inventors found that the compound represented by the general formula (I) of the present invention or a salt thereof is useful as an agrohorticultural fungicide to complete the present invention.

Abstract: A drug containing, as an active ingredient, a compound represented by ALK inhibitors such as brigatinib, AP26113-analog, and AZD3463 has been found to be effective against a non-small cell lung cancer having a point mutation at C797S in EGFR which has acquired a resistance to chemotherapy agents. Further, the drug used in combination with an anti-EGFR antibody demonstrates a notable suppression effect on the tumor growth. The drug has a potential to be a therapeutic agent effective against a non-small cell lung cancer which is resistant to gefitinib, a first generation therapeutic agent and osimertinib, a third generation therapeutic agent.

Abstract: In production of crops of agriculture and horticulture or the like, damage caused by diseases is still large, and, due to factors such as occurrence of resistant diseases to existing drugs, development of new agrohorticultural fungicides is desired. The present invention provides an agrohorticultural fungicide and a method of use thereof, an active ingredient thereof being a compound represented by the general formula (I) or salts thereof: {wherein R1 denotes a hydrogen atom or (C1-C6)alkyl group or the like. R2 denotes a hydrogen atom or the like. R3 denotes a hydrogen atom or (C1-C6)alkyl group or the like. R4 denotes a (C1-C6)alkyl group, (C3-C6)cycloalkyl group or aryl group or the like. X1 and X2 denote a hydrogen atom or halogen atom or the like. Y denotes an oxygen atom.}.

Abstract: An electrical discharge machining method includes selectively immersing only a portion of a workpiece in an electrical discharge machining liquid such that a machining object portion included in the portion of the workpiece is opposed to an electrode immersed in the electrical discharge machining liquid and applying an electrical discharge machining to the machining object portion by applying a voltage between the electrode and the workpiece in a state where the portion of the workpiece is selectively immersed in the electrical discharge machining liquid.