Patents by Inventor Naoya Shinozaki

Naoya Shinozaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11952423
    Abstract: A novel antibody that can be used as an anti-tumor agent and an anti-tumor agent that comprises, as an active ingredient, a molecule containing such an antibody.
    Type: Grant
    Filed: May 16, 2023
    Date of Patent: April 9, 2024
    Assignees: MIE UNIVERSITY, DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Hiroshi Shiku, Yasushi Akahori, Kento Tanaka, Ayaka Yatsu, Junya Ichikawa, Toshiaki Ohtsuka, Shiho Kozuma, Ryuji Hashimoto, Makiko Nakayama, Naoya Shinozaki, Kensuke Nakamura, Ichiro Watanabe, Shinji Furuzono
  • Publication number: 20230348616
    Abstract: An antibody that can be used as an anti-tumor agent and an anti-tumor agent comprises a molecule containing such an antibody. Such an antibody or a binding fragment thereof comprises: a heavy chain CDRH1 consisting of SEQ ID NO: 54, a heavy chain CDRH2 consisting of SEQ ID NO: 55, a heavy chain CDRH3 consisting of SEQ ID NO: 56, a light chain CDRL1 consisting of SEQ ID NO: 57 or a light chain CDRL1 consisting of an amino acid sequence derived from SEQ ID NO: 57 in which amino acid 7 is W and/or amino acid 8 is K, a light chain CDRL2 consisting of SEQ ID NO: 58, and a light chain CDRL3 consisting of SEQ ID NO: 59 or a light chain CDRL3 consisting of an amino acid sequence derived from SEQ ID NO: 59 in which amino acid 2 is A or S.
    Type: Application
    Filed: March 29, 2021
    Publication date: November 2, 2023
    Applicants: MIE UNIVERSITY, DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Hiroshi SHIKU, Yasushi AKAHORI, Kento TANAKA, Ayaka YATSU, Junya ICHIKAWA, Toshiaki OHTSUKA, Shiho KOZUMA, Ryuji HASHIMOTO, Makiko NAKAYAMA, Naoya SHINOZAKI, Kensuke NAKAMURA, Ichiro WATANABE, Shinji FURUZONO
  • Publication number: 20230287121
    Abstract: A novel antibody that can be used as an anti-tumor agent and an anti-tumor agent that comprises, as an active ingredient, a molecule containing such an antibody.
    Type: Application
    Filed: May 16, 2023
    Publication date: September 14, 2023
    Applicants: MIE UNIVERSITY, DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Hiroshi SHIKU, Yasushi AKAHORI, Kento TANAKA, Ayaka YATSU, Junya ICHIKAWA, Toshiaki OHTSUKA, Shiho OKZUMA, Ryuji HASHIMOTO, Makiko NAKAYAMA, Naoya SHINOZAKI, Kensuke NAKAMURA, Ichiro WATANABE, Shinji FURUZONO
  • Publication number: 20170305988
    Abstract: The present invention provides a peptide selected from the following (i) and (ii): (i) a peptide having the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing; and (ii) a peptide having an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing by the conservative amino acid substitution, deletion, addition, or insertion of 1 to 28 (inclusive) amino acids except at the 1st Xaa to the 11th Xaa counting from the amino terminus.
    Type: Application
    Filed: July 10, 2017
    Publication date: October 26, 2017
    Inventors: Tohru TAKAHASHI, Naoya SHINOZAKI, Takeshi TAKIZAWA, Takako KIMURA
  • Patent number: 9708382
    Abstract: The present invention provides a peptide library comprising a plurality of mutant peptides based on the extracellular binding domain of the TACI protein. The mutant peptides of the library have the capacity to bind to target molecules other than the endogenous TACI ligands. The present invention further provides a peptide library comprising a plurality of mutant peptides each comprising an amino acid sequence of SEQ ID NO: 1 in the Sequence Listing.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: July 18, 2017
    Assignee: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Tohru Takahashi, Naoya Shinozaki, Takeshi Takizawa, Takako Kimura
  • Publication number: 20150308886
    Abstract: A platform scale provided with an enclosure for surrounding the sides of the platform scale, wherein: the platform scale comprises shock-absorbing members that extend outward at multiple places of the feet, which support the main body of the platform scale on a base; the enclosure is configured from only side walls that surround the sides of the platform scale; the height of the side walls placed on the base is set to be lower than the height of the upper surface of the weighing tray of the platform scale; and the side walls set on the base do not touch portions of the platform scale other than the shock-absorbing members.
    Type: Application
    Filed: August 26, 2013
    Publication date: October 29, 2015
    Applicant: SHINKO DENSHI CO., LTD.
    Inventors: Naoya Shinozaki, Kazufumi Naito, Tsubasa Takanami
  • Patent number: 8853568
    Abstract: (Problem) To provide a high precision platform scale (Means to Solve the Problem) A platform scale for weighing an object to be weighed by supporting it by a plurality of load detection sections, wherein the load detection section comprises a load sensor 40 having a block body 42 for transmitting an applied load to a tuning fork vibrator 41 coupled to the block body 42 by reducing the load, a circuit board having fabricated thereon circuitry for converting a signal from the tuning fork vibrator into a digital signal and a sensor case 33 for accommodating the load sensor and the circuit board. The sensor case 33 is made by casting stainless material by a lost wax process and is directly coupled to parallel base frames 20 for maintaining the distance between the base frames. The sensor case has sufficient mechanical strength and also acts as a structural member for the base frames, thereby reducing the number of components and the height of a weighing table.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: October 7, 2014
    Assignee: Shinko Denshi Co., Ltd.
    Inventors: Naoya Shinozaki, Shinichiro Ishida, Kazufumi Naito
  • Patent number: 8770044
    Abstract: A load detection sensor capable of stably weighing a heavy object to be weighed in high precision. The load detection sensor according to the present invention includes a force sensor including a tuning fork vibrator and a block body that has a rectangular parallelepiped outer shape and transmits an applied load to the force sensor by using a lever to reduce the load. It is characterized in that the block body contains therein a lever mechanism and a Roberval mechanism by working on the longitudinal side thereof and that the force sensor is coupled to the side of the block body. Although the block body is cut and ground in the side for fabricating the lever mechanism and the Roberval mechanism, it maintains the rectangular parallelepiped outer shape and sufficient mechanical strength, thereby enabling to stably reduce the applied load.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: July 8, 2014
    Assignee: Shinko Denshi Co., Ltd.
    Inventor: Naoya Shinozaki
  • Publication number: 20130316929
    Abstract: The present invention provides a peptide selected from the following (i) and (ii): (i) a peptide having the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing; and (ii) a peptide having an amino acid sequence derived from the amino acid sequence represented by SEQ ID NO: 1 in the Sequence Listing by the conservative amino acid substitution, deletion, addition, or insertion of 1 to (inclusive) amino acids except at the 1st Xaa to the 11th Xaa counting from the amino terminus.
    Type: Application
    Filed: August 1, 2013
    Publication date: November 28, 2013
    Applicant: Daiichi Sankyo Company, Limited
    Inventors: Tohru TAKAHASHI, Naoya SHINOZAKI, Takeshi TAKIZAWA, Takako KIMURA
  • Publication number: 20120080241
    Abstract: A platform scale for weighing an object to be weighed by supporting it by a plurality of load detection sections, wherein the load detection section comprises a load sensor 40 having a block body 42 for transmitting an applied load to a tuning fork vibrator 41 coupled to the block body 42 by reducing the load, a circuit board having fabricated thereon circuitry for converting a signal from the tuning fork vibrator into a digital signal and a sensor case 33 for accommodating the load sensor and the circuit board. The sensor case 33 is made by casting stainless material by a lost wax process and is directly coupled to parallel base frames 20 for maintaining the distance between the base frames. The sensor case has sufficient mechanical strength and also acts as a structural member for the base frames, thereby reducing the number of components and the height of a weighing table.
    Type: Application
    Filed: June 23, 2010
    Publication date: April 5, 2012
    Applicant: SHINKO DENSHI CO., LTD.
    Inventors: Naoya Shinozaki, Shinichiro Ishida, Kazufumi Naito
  • Publication number: 20120073387
    Abstract: (Problem) To provide a load detection sensor capable of stably weighing a heavy object to be weighed in high precision (Means to solve the problem) The load detection sensor 40 according to the present invention comprises a force sensor 41 including a tuning fork vibrator and a block body 42 that has a rectangular parallelepiped outer shape and transmits an applied load to the force sensor by using a lever to reduce the load. It is characterized in that the block body 42 contains therein a lever mechanism and a Roberval mechanism by working on the longitudinal side thereof and that the force sensor 41 is coupled to the side of the block body 42. Although the block body is cut and ground in the side for fabricating the lever mechanism and the Roberval mechanism, it maintains the rectangular parallelepiped outer shape and sufficient mechanical strength, thereby enabling to stably reduce the applied load.
    Type: Application
    Filed: June 23, 2010
    Publication date: March 29, 2012
    Applicant: SHINKO DENSHI CO., LTD.
    Inventor: Naoya Shinozaki