Abstract: The present invention relates to S-allylmercapto-N-acetylcysteine (ASSNAC) and its pharmaceutically acceptable salts and solvates, which are useful for up-regulation of cellular glutathione levels and expression of phase II detoxifying enzymes. The invention further provides methods of use thereof in the prevention, alleviation or treatment of oxidative stress induced by reactive oxygen species (ROS).

Abstract: There is provided compositions-of-matter comprising fibrin or fibrinogen crosslinked with at least one reducing sugar.

Abstract: The present invention relates to S-allylmercapto-N-acetylcysteine (ASSNAC) and its pharmaceutically acceptable salts and solvates, which are useful for up-regulation of cellular glutathione levels and expression of phase II detoxifying enzymes. The invention further provides methods of use thereof in the prevention, alleviation or treatment of oxidative stress induced by reactive oxygen species (ROS).

Abstract: A pharmaceutical composition for the treatment of disorders of the anterior segment of the eye or for the preservation of isolated cornea. The composition comprises, as an active ingredient, an agent capable of causing a net efflux of cholesterol from cells.

Abstract: A device for analyzing liquid body-specimens, the device comprising at least one specimen handling station for obtaining preparation on a carrying media, and an imaging station fitted with an optical image capturing device for analyzing the preparation. A carriage with a carrying media receptacle rotatably retains the carrying media and is displaceable between a loading position and an unloading position with respective positions at the stations. An incremental displacement mechanism for displacing at least one of the carrying media and an imaging device so as to obtain at least one consecutive image of the preparation.

Abstract: An inhibitor of cholesterol synthesis is used for the treatment, alleviation or prevention of skin disorders.

Abstract: An inhibitor of cholesterol synthesis is used for the treatment, alleviation or prevention of skin disorders.

Abstract: A method for determining a platelet function in a primary hemostasis is provided in which a blood sample or a platelet containing fraction thereof is introduced into a vessel having a flat bottom which has an inner surface covered with a substrate capable of inducing platelet adhesion thereto and aggregation such as ECM (extracellular matrix). Preparation is then rotated inside the vessel, and consequently shear forces develop on the surface which bring to adhesion an aggregation of the blood platelets to the surface. Morphological parameters of blood aggregates are then determined.

Abstract: The invention relates to compositions which induce in humans regeneration of the corneal endothelium. The compositions of the invention are of value in regenerating the corneal endothelium in humans, which is frequently damaged in the course of eye surgery and injuries. Such regeneration is very important to ensure the full functionality of the eye. The compositions of the invention comprise as active ingredient an adequate quantity of fibroblast growth factor (FGF) in a suitable physiologically acceptable vehicle. A preferred embodiment of the invention relates to a composition containing a certain quantity of hyaluronic acid and any other viscoelastic agent.