Patents by Inventor Narasimha Kumar
Narasimha Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240113986Abstract: Various embodiments include an automobile network device that includes a descriptor sorting engine (DSE). The DSE may include a direct memory access (DMA) controller, a memory organized by channel clusters that each include a plurality of first-in first-out (FIFO) memories, a timer, and a time stamp (TS) sorting logic component. The DMA controller may be configured to pull timestamp-pointer pairs from packet descriptors stored in an unsorted descriptor ring memory, store the timestamp-pointer pairs in the FIFO memories, trigger the TS sorting logic component to reorder the timestamp-pointer pairs in the FIFO memories so that they are sorted in ascending order, use the sorted timestamp-pointer pairs in the FIFO memories to read the packet descriptors stored in an unsorted descriptor ring memory, and store the packet descriptors in a sorted descriptor ring memory.Type: ApplicationFiled: October 3, 2022Publication date: April 4, 2024Inventors: Narasimha Rao KORAMUTLA, Arun GOTHEKAR, Susheel Kumar Yadav YADAGIRI, Akshat GUPTA, Srinivas MARAKALA, Naveen Kumar NARALA, Radvajesh MUNIBYRAIAH
-
Publication number: 20240038488Abstract: Described herein are techniques for identifying biological structures using a cryogenic electron microscopy (cryo-EM). In some embodiments, first images captured at a first magnification level may be received depicting cryo-EM grid units. Using a first ML model, one or more cryo-EM grid units may be detected based on the first images. Second images of each cryo-EM grid unit captured at a second magnification level may be received and, using a second ML model, one or more apertures within the cryo-EM grid may be detected based on the second images. One or more images captured at a third magnification level of depicting at least one of ice or a biological structure suspended within each aperture may be received and a Fourier transformation may be generated. Using a third ML model, at least one image depicting the biological structure from the images may be identified based on the Fourier transformations.Type: ApplicationFiled: August 1, 2023Publication date: February 1, 2024Inventors: Narasimha KUMAR, Elliot Marshall GRAY, Charles Alexandro RICE
-
Publication number: 20230416721Abstract: Methods of reducing survival of cancer cells in a subject by applying alternating electric fields to the cancer cells and delivering at least one of an E2F inhibitor and a CDK4/6 inhibitor to the cancer cells are provided. In some instances, alternating electric fields are applied to the cancer cells at a frequency between 80 and 300 kHz. In some instances, at least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some aspects, the alternating electric fields are applied to the cancer cells for at least 72 hours.Type: ApplicationFiled: July 12, 2023Publication date: December 28, 2023Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Michael D. STORY, Narasimha Kumar KARANAM
-
Publication number: 20230347173Abstract: A method of treating a tumor in a subject, the method comprises applying a tumor treating field to the tumor at a frequency between approximately 50 kHz and approximately 1,000 kHz; and delivering personalized ultra-fractionated adaptive radiotherapy (PULSAR) regimen.Type: ApplicationFiled: March 31, 2023Publication date: November 2, 2023Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Michael D. STORY, Debabrata SAHA, Narasimha Kumar KARANAM
-
Publication number: 20220288404Abstract: A method of treating a tumor in a subject, the method comprises delivering an ATR inhibitor to the tumor, and applying a tumor treating field to the tumor at a frequency between approximately 50 kHz and approximately 1,000 kHz.Type: ApplicationFiled: March 11, 2022Publication date: September 15, 2022Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Michael D. STORY, Narasimha Kumar KARANAM
-
Publication number: 20210292741Abstract: Methods of reducing survival of cancer cells in a subject by applying alternating electric fields to the cancer cells and delivering at least one of an E2F inhibitor and a CDK4/6 inhibitor to the cancer cells are provided. In some instances, alternating electric fields are applied to the cancer cells at a frequency between 80 and 300 kHz. In some instances, at least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some aspects, the alternating electric fields are applied to the cancer cells for at least 72 hours.Type: ApplicationFiled: March 22, 2021Publication date: September 23, 2021Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEMInventors: Michael D. STORY, Narasimha Kumar KARANAM
-
Publication number: 20210268247Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.Type: ApplicationFiled: February 11, 2021Publication date: September 2, 2021Inventors: Michael STORY, Debabrata SAHA, Narasimha Kumar KARANAM
-
Patent number: 11080684Abstract: An example relates to a method for processing data an on smartcard comprising: (i) obtaining a message; (ii) searching for a rule in at least one file of the smartcard based on the message; and (iii) in case the rule was found, executing the rule.Type: GrantFiled: December 8, 2014Date of Patent: August 3, 2021Assignee: Infineon Technologies AGInventors: Bala Nagendra Raja Munjuluri, Franz-Josef Brücklmayr, Narasimha Kumar Vedala, Prakash Nayak
-
Patent number: 10953209Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.Type: GrantFiled: March 28, 2018Date of Patent: March 23, 2021Assignee: Board of Regents of the University of Texas SystemInventors: Michael Story, Debabrata Saha, Narasimha Kumar Karanam
-
Publication number: 20190298982Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.Type: ApplicationFiled: March 28, 2018Publication date: October 3, 2019Inventors: Michael Story, Debabrata Saha, Narasimha Kumar Karanam
-
Patent number: 9910794Abstract: A method for executing a program code is suggested, the method comprising: checking a memory access policy resource based on a trigger; and comparing a current program counter with a program counter information provided by the memory access policy resource and, in case the comparison of the current program counter and the program counter information fulfills a predefined condition, conducting a memory access policy check to allow permitted operations.Type: GrantFiled: September 26, 2014Date of Patent: March 6, 2018Assignee: Infineon Technologies AGInventors: Narasimha Kumar Vedala, Bala Nagendra Raja Munjuluri, Prakash Nayak
-
Patent number: 9852083Abstract: A method for executing a program code is suggested, the method comprising: checking a memory access policy resource based on a trigger; and comparing a current program counter with a program counter information provided by the memory access policy resource and, in case the comparison of the current program counter and the program counter information fulfills a predefined condition, conducting a memory access policy check to allow permitted operations.Type: GrantFiled: September 26, 2014Date of Patent: December 26, 2017Assignee: Infineon Technologies AGInventors: Narasimha Kumar Vedala, Bala Nagendra Raja Munjuluri, Prakash Nayak
-
Publication number: 20160162881Abstract: An example relates to a method for processing data an on smartcard comprising: (i) obtaining a message; (ii) searching for a rule in at least one file of the smartcard based on the message; and (iii) in case the rule was found, executing the rule.Type: ApplicationFiled: December 8, 2014Publication date: June 9, 2016Inventors: Bala Nagendra Raja MUNJULURI, Franz-Josef BRUECKLMAYR, Narasimha Kumar VEDALA, Prakash NAYAK
-
Publication number: 20160092378Abstract: A method for executing a program code is suggested, the method comprising: checking a memory access policy resource based on a trigger; and comparing a current program counter with a program counter information provided by the memory access policy resource and, in case the comparison of the current program counter and the program counter information fulfills a predefined condition, conducting a memory access policy check to allow permitted operations.Type: ApplicationFiled: September 26, 2014Publication date: March 31, 2016Inventors: Narasimha Kumar VEDALA, Bala Nagendra Raja MUNJULURI, Prakash NAYAK
-
Patent number: 8298789Abstract: The present invention discloses a process for the preparation of rhPTH (1-34) also known as teriparatide by construction of a novel nucleotide, as an NcoI.IXhoI fragment as set forth in SEQ. ID. No.:1 encoding a chimeric fusion protein as set forth in SEQ.ID. No.:2 comprising of a fusion partner consisting of 41 amino acids belonging to Escherichia coli ?-galactosidase (LacZ) gene, an endopeptidase cleavage site, rhPTH (1-34) gene fragment, cloning the said nucleotide in an expression vector under the control of T7 promoter, transforming Escherichia coli with the said vector and expressing the chimeric fusion protein in fed batch fermentation. The present invention further discloses a low feed rate lactose induction for optimized expression of rhPTH (1-34) in Escherichia coli.Type: GrantFiled: December 6, 2007Date of Patent: October 30, 2012Assignee: USV LimitedInventors: Uma Sankararaman, Dipanwita Maiti, Meera Sankarankutty, Rakesh Shekhawat, Narasimha Kumar Kopparapu, Gulnaz Zaidi, Bipinchandra Rathod, Niren Praful Thakar, Priti Thakur, Anjali Chutke, Shrikant Mishra
-
Publication number: 20100145033Abstract: The present invention discloses a process for the preparation of rhPTH (1-34) also known as teriparatide by con-struction of a novel nucleotide, as an NcoI.IXhoI fragemt as set forth in SEQ. ID. No.:1 encoding a chimeric fusion protein as set forth in SEQ.ID. No.:2 comprising of a fusion partner consisting of 41 amino acids belonging to Escherichia coli ?-galactosidase (LacZ) gene, an endopeptidase cleavage site, rhPTH (1-34) gene fragment, cloning the said nucleotide in an expression vector under the control of T7 promoter, transforming Escherichia coli with the said vector and expressing the chimeric fusion protein in fed batch fermentation. The present invention further discloses a low feed rate lactose induction for optimized expression of rhPTH (1-34) in Escherichia coli.Type: ApplicationFiled: December 6, 2007Publication date: June 10, 2010Applicant: USV LimitedInventors: Uma Sankararaman, Dipanwita Maiti, Meera Sankarankutty, Rakesh Shekhawat, Narasimha Kumar Kopparapu, Gulnaz Zaidi, Bipinchandra Rathod, Niren Praful Thakar, Priti Thakur, Anjali Chutke, Shrikant Mishra
-
Patent number: 5903752Abstract: An improved method and apparatus for embedding a real-time multi-tasking kernel in a non-real-time operating system is disclosed. Through encapsulating a real-time kernel into the interrupt handling environment of a non-real-time operating system, such as Windows.RTM., the method of the present invention allows for an entire real-time environment to be supported within the operating system. The scheduler of the real-time kernel supports multiple threads of execution all running at higher priority than the application tasks. By using synchronization mechanisms of the operating system, e.g. VxD events in enhanced mode Windows.RTM., the real-time tasks are able to make use of system services of the operating system. Real-time tasks not requiring system services execute more quickly from interrupt mode. Real-time tasks requiring system services execute partially from interrupt mode and partially from event mode.Type: GrantFiled: October 17, 1996Date of Patent: May 11, 1999Assignee: Intel CorporationInventors: Thomas J. Dingwall, Narasimha Kumar