Patents by Inventor Narasimha Kumar

Narasimha Kumar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240113986
    Abstract: Various embodiments include an automobile network device that includes a descriptor sorting engine (DSE). The DSE may include a direct memory access (DMA) controller, a memory organized by channel clusters that each include a plurality of first-in first-out (FIFO) memories, a timer, and a time stamp (TS) sorting logic component. The DMA controller may be configured to pull timestamp-pointer pairs from packet descriptors stored in an unsorted descriptor ring memory, store the timestamp-pointer pairs in the FIFO memories, trigger the TS sorting logic component to reorder the timestamp-pointer pairs in the FIFO memories so that they are sorted in ascending order, use the sorted timestamp-pointer pairs in the FIFO memories to read the packet descriptors stored in an unsorted descriptor ring memory, and store the packet descriptors in a sorted descriptor ring memory.
    Type: Application
    Filed: October 3, 2022
    Publication date: April 4, 2024
    Inventors: Narasimha Rao KORAMUTLA, Arun GOTHEKAR, Susheel Kumar Yadav YADAGIRI, Akshat GUPTA, Srinivas MARAKALA, Naveen Kumar NARALA, Radvajesh MUNIBYRAIAH
  • Publication number: 20240038488
    Abstract: Described herein are techniques for identifying biological structures using a cryogenic electron microscopy (cryo-EM). In some embodiments, first images captured at a first magnification level may be received depicting cryo-EM grid units. Using a first ML model, one or more cryo-EM grid units may be detected based on the first images. Second images of each cryo-EM grid unit captured at a second magnification level may be received and, using a second ML model, one or more apertures within the cryo-EM grid may be detected based on the second images. One or more images captured at a third magnification level of depicting at least one of ice or a biological structure suspended within each aperture may be received and a Fourier transformation may be generated. Using a third ML model, at least one image depicting the biological structure from the images may be identified based on the Fourier transformations.
    Type: Application
    Filed: August 1, 2023
    Publication date: February 1, 2024
    Inventors: Narasimha KUMAR, Elliot Marshall GRAY, Charles Alexandro RICE
  • Publication number: 20230416721
    Abstract: Methods of reducing survival of cancer cells in a subject by applying alternating electric fields to the cancer cells and delivering at least one of an E2F inhibitor and a CDK4/6 inhibitor to the cancer cells are provided. In some instances, alternating electric fields are applied to the cancer cells at a frequency between 80 and 300 kHz. In some instances, at least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some aspects, the alternating electric fields are applied to the cancer cells for at least 72 hours.
    Type: Application
    Filed: July 12, 2023
    Publication date: December 28, 2023
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michael D. STORY, Narasimha Kumar KARANAM
  • Publication number: 20230347173
    Abstract: A method of treating a tumor in a subject, the method comprises applying a tumor treating field to the tumor at a frequency between approximately 50 kHz and approximately 1,000 kHz; and delivering personalized ultra-fractionated adaptive radiotherapy (PULSAR) regimen.
    Type: Application
    Filed: March 31, 2023
    Publication date: November 2, 2023
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michael D. STORY, Debabrata SAHA, Narasimha Kumar KARANAM
  • Publication number: 20220288404
    Abstract: A method of treating a tumor in a subject, the method comprises delivering an ATR inhibitor to the tumor, and applying a tumor treating field to the tumor at a frequency between approximately 50 kHz and approximately 1,000 kHz.
    Type: Application
    Filed: March 11, 2022
    Publication date: September 15, 2022
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michael D. STORY, Narasimha Kumar KARANAM
  • Publication number: 20210292741
    Abstract: Methods of reducing survival of cancer cells in a subject by applying alternating electric fields to the cancer cells and delivering at least one of an E2F inhibitor and a CDK4/6 inhibitor to the cancer cells are provided. In some instances, alternating electric fields are applied to the cancer cells at a frequency between 80 and 300 kHz. In some instances, at least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some aspects, the alternating electric fields are applied to the cancer cells for at least 72 hours.
    Type: Application
    Filed: March 22, 2021
    Publication date: September 23, 2021
    Applicant: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Michael D. STORY, Narasimha Kumar KARANAM
  • Publication number: 20210268247
    Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.
    Type: Application
    Filed: February 11, 2021
    Publication date: September 2, 2021
    Inventors: Michael STORY, Debabrata SAHA, Narasimha Kumar KARANAM
  • Patent number: 11080684
    Abstract: An example relates to a method for processing data an on smartcard comprising: (i) obtaining a message; (ii) searching for a rule in at least one file of the smartcard based on the message; and (iii) in case the rule was found, executing the rule.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: August 3, 2021
    Assignee: Infineon Technologies AG
    Inventors: Bala Nagendra Raja Munjuluri, Franz-Josef Brücklmayr, Narasimha Kumar Vedala, Prakash Nayak
  • Patent number: 10953209
    Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.
    Type: Grant
    Filed: March 28, 2018
    Date of Patent: March 23, 2021
    Assignee: Board of Regents of the University of Texas System
    Inventors: Michael Story, Debabrata Saha, Narasimha Kumar Karanam
  • Publication number: 20190298982
    Abstract: Tumor-Treating Fields elicit a conditional vulnerability to PARP inhibitors (e.g., Olaparib) in certain cancer cells such as non-small cell lung cancer (NSCLC) cell lines. This conditional vulnerability is exploited in a method of killing cancer cells that comprises delivering a PARP inhibitor to the cancer cells and applying an alternating 80-300 kHz electric field to the cancer cells. At least a portion of the applying step is performed simultaneously with at least a portion of the delivering step. In some embodiments, an additional step of treating the cancer cells with a radiation therapy is added to the method. In some embodiments, the frequency of the alternating electric field is between 100 and 200 kHz.
    Type: Application
    Filed: March 28, 2018
    Publication date: October 3, 2019
    Inventors: Michael Story, Debabrata Saha, Narasimha Kumar Karanam
  • Patent number: 9910794
    Abstract: A method for executing a program code is suggested, the method comprising: checking a memory access policy resource based on a trigger; and comparing a current program counter with a program counter information provided by the memory access policy resource and, in case the comparison of the current program counter and the program counter information fulfills a predefined condition, conducting a memory access policy check to allow permitted operations.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: March 6, 2018
    Assignee: Infineon Technologies AG
    Inventors: Narasimha Kumar Vedala, Bala Nagendra Raja Munjuluri, Prakash Nayak
  • Patent number: 9852083
    Abstract: A method for executing a program code is suggested, the method comprising: checking a memory access policy resource based on a trigger; and comparing a current program counter with a program counter information provided by the memory access policy resource and, in case the comparison of the current program counter and the program counter information fulfills a predefined condition, conducting a memory access policy check to allow permitted operations.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: December 26, 2017
    Assignee: Infineon Technologies AG
    Inventors: Narasimha Kumar Vedala, Bala Nagendra Raja Munjuluri, Prakash Nayak
  • Publication number: 20160162881
    Abstract: An example relates to a method for processing data an on smartcard comprising: (i) obtaining a message; (ii) searching for a rule in at least one file of the smartcard based on the message; and (iii) in case the rule was found, executing the rule.
    Type: Application
    Filed: December 8, 2014
    Publication date: June 9, 2016
    Inventors: Bala Nagendra Raja MUNJULURI, Franz-Josef BRUECKLMAYR, Narasimha Kumar VEDALA, Prakash NAYAK
  • Publication number: 20160092378
    Abstract: A method for executing a program code is suggested, the method comprising: checking a memory access policy resource based on a trigger; and comparing a current program counter with a program counter information provided by the memory access policy resource and, in case the comparison of the current program counter and the program counter information fulfills a predefined condition, conducting a memory access policy check to allow permitted operations.
    Type: Application
    Filed: September 26, 2014
    Publication date: March 31, 2016
    Inventors: Narasimha Kumar VEDALA, Bala Nagendra Raja MUNJULURI, Prakash NAYAK
  • Patent number: 8298789
    Abstract: The present invention discloses a process for the preparation of rhPTH (1-34) also known as teriparatide by construction of a novel nucleotide, as an NcoI.IXhoI fragment as set forth in SEQ. ID. No.:1 encoding a chimeric fusion protein as set forth in SEQ.ID. No.:2 comprising of a fusion partner consisting of 41 amino acids belonging to Escherichia coli ?-galactosidase (LacZ) gene, an endopeptidase cleavage site, rhPTH (1-34) gene fragment, cloning the said nucleotide in an expression vector under the control of T7 promoter, transforming Escherichia coli with the said vector and expressing the chimeric fusion protein in fed batch fermentation. The present invention further discloses a low feed rate lactose induction for optimized expression of rhPTH (1-34) in Escherichia coli.
    Type: Grant
    Filed: December 6, 2007
    Date of Patent: October 30, 2012
    Assignee: USV Limited
    Inventors: Uma Sankararaman, Dipanwita Maiti, Meera Sankarankutty, Rakesh Shekhawat, Narasimha Kumar Kopparapu, Gulnaz Zaidi, Bipinchandra Rathod, Niren Praful Thakar, Priti Thakur, Anjali Chutke, Shrikant Mishra
  • Publication number: 20100145033
    Abstract: The present invention discloses a process for the preparation of rhPTH (1-34) also known as teriparatide by con-struction of a novel nucleotide, as an NcoI.IXhoI fragemt as set forth in SEQ. ID. No.:1 encoding a chimeric fusion protein as set forth in SEQ.ID. No.:2 comprising of a fusion partner consisting of 41 amino acids belonging to Escherichia coli ?-galactosidase (LacZ) gene, an endopeptidase cleavage site, rhPTH (1-34) gene fragment, cloning the said nucleotide in an expression vector under the control of T7 promoter, transforming Escherichia coli with the said vector and expressing the chimeric fusion protein in fed batch fermentation. The present invention further discloses a low feed rate lactose induction for optimized expression of rhPTH (1-34) in Escherichia coli.
    Type: Application
    Filed: December 6, 2007
    Publication date: June 10, 2010
    Applicant: USV Limited
    Inventors: Uma Sankararaman, Dipanwita Maiti, Meera Sankarankutty, Rakesh Shekhawat, Narasimha Kumar Kopparapu, Gulnaz Zaidi, Bipinchandra Rathod, Niren Praful Thakar, Priti Thakur, Anjali Chutke, Shrikant Mishra
  • Patent number: 5903752
    Abstract: An improved method and apparatus for embedding a real-time multi-tasking kernel in a non-real-time operating system is disclosed. Through encapsulating a real-time kernel into the interrupt handling environment of a non-real-time operating system, such as Windows.RTM., the method of the present invention allows for an entire real-time environment to be supported within the operating system. The scheduler of the real-time kernel supports multiple threads of execution all running at higher priority than the application tasks. By using synchronization mechanisms of the operating system, e.g. VxD events in enhanced mode Windows.RTM., the real-time tasks are able to make use of system services of the operating system. Real-time tasks not requiring system services execute more quickly from interrupt mode. Real-time tasks requiring system services execute partially from interrupt mode and partially from event mode.
    Type: Grant
    Filed: October 17, 1996
    Date of Patent: May 11, 1999
    Assignee: Intel Corporation
    Inventors: Thomas J. Dingwall, Narasimha Kumar