Publication number: 20240309017
Abstract: The present invention generally relates to a process for purification of (2R,5S,13aR)-8-methoxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1?,2?:4,5] pyrazino [2,1-b] [1,3] oxazepine-10-carboxylic acid of Formula I and (2R,5S,13aR)-8-methoxy-7,9-dioxo-N-[(2,4,6-trifluorophenyl)methyl)]-2,3,4,5,7,9,13,13a-octahydro-2,5-methano pyrido-[1?,2?:4,5] pyrazino[2,1-b] [1,3]-oxazepine-10-carboxamide of Formula II, an intermediates for the preparation of bictegravir.
Type:
Application
Filed:
July 21, 2021
Publication date:
September 19, 2024
Inventors:
Raja Babu BALUSU, Ram THAIMATTAM, Giri Babu PEDDINTI, Nagarjuna PODILE, Venkata Lakshmi Narasimha Rao DAMMALAPATI, Uma Maheswar Rao VASIREDDI