Patents by Inventor Narasimha Rao Krishnamurthy

Narasimha Rao Krishnamurthy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline Structure of FABI from Burkholderia Pseudomallei
    Publication number: 20170088822
    Abstract: The present invention relates to drug targets for Burkholderia pseudomallei. The invention provides a crystalline polypeptide derived from Burkholderia pseudomallei comprising the amino acid sequence set forth in SEQ ID NO: 1. Also provided are methods for co-crystallizing a binary enoyl-acyl carrier protein reductase (FabI) with a potential inhibitor of an FabI activity and for identifying an inhibitor of an activity of enoyl-acyl carrier protein reductase (FabI). A representative example of such a crystalline structure is a BpmFabI:AFN-1252 complex.
    Type: Application
    Filed: September 30, 2015
    Publication date: March 30, 2017
    Applicant: AURIGENE DISCOVERY TECHNOLOGIES LIMITED
    Inventors: Narasimha Rao Krishnamurthy, Anirudha Lakshminarasimhan, Thomas Antony, Hosahalli S. Subramanya