Patents by Inventor Narayan Chaudhuri

Narayan Chaudhuri has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230331751
    Abstract: The present invention provides stereoselective processes of manufacture for the phosphoramidate nucleotide Compound 1 or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: February 17, 2023
    Publication date: October 19, 2023
    Applicant: Atea Pharmaceuticals, Inc.
    Inventors: Adel Moussa, Narayan Chaudhuri
  • Patent number: 7598373
    Abstract: The present invention provides an improved process for preparing 2-C-methyl-D-ribonolactone.
    Type: Grant
    Filed: December 12, 2003
    Date of Patent: October 6, 2009
    Assignee: Idenix Pharmaceuticals, Inc.
    Inventors: Richard Storer, Adel M. Moussa, Narayan Chaudhuri, Frank Waligora
  • Publication number: 20050059632
    Abstract: An improved process for the preparation of 2?-modified nucleosides and 2?-deoxy-nucleosides, such as, ?-L-2?-deoxy-thymidine (LdT), is provided. In particular, the improved process is directed to the synthesis of a 2?-deoxynucleoside that may utilize different starting materials but that proceeds via a chloro-sugar intermediate or via a 2,2?-anhydro-1-furanosyl-nucleobase intermediate. Where an 2,2?-anhydro-1-furanosyl base intermediate is utilized, a reducing agent, such as Red-Al, and a sequestering agent, such as 15-crown-5 ether, that cause an intramolecular displacement reaction and formation of the desired nucleoside product in good yields are employed. An alternative process of the present invention utilizes a 2,2?-anhydro-1-furanosyl base intermediate without a sequestering agent to afford 2?-deoxynucleosides in good yields.
    Type: Application
    Filed: June 30, 2004
    Publication date: March 17, 2005
    Inventors: Richard Storer, Adel Moussa, Jingyang Wang, Narayan Chaudhuri, Steven Mathieu, Alistair Stewart
  • Publication number: 20050020825
    Abstract: The present invention provides an improved process for preparing ?-D and ?-L 2?-C-methyl-nucleosides and 2?-C-methyl-3?-O-ester nucleosides.
    Type: Application
    Filed: December 12, 2003
    Publication date: January 27, 2005
    Inventors: Richard Storer, Adel Moussa, Narayan Chaudhuri, Frank Waligora