Patents by Inventor Narendra Nath Tandon
Narendra Nath Tandon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12370219Abstract: Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.Type: GrantFiled: March 7, 2025Date of Patent: July 29, 2025Assignee: Cellphire, Inc.Inventors: Keith Andrew Moskowitz, Braden Carl Ishler, William Matthew Dickerson, Narendra Nath Tandon, Amber Nicole Lee, Stephen Edward Amos, Rafael Jorda, Michael Alexander Mathews
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Publication number: 20250205284Abstract: Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.Type: ApplicationFiled: March 7, 2025Publication date: June 26, 2025Applicant: Cellphire, Inc.Inventors: Keith Andrew MOSKOWITZ, Braden Carl ISHLER, William Matthew DICKERSON, Narendra Nath TANDON, Amber Nicole LEE, Stephen Edward AMOS, Rafael JORDA, Michael Alexander MATHEWS
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Patent number: 12295972Abstract: Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.Type: GrantFiled: August 20, 2024Date of Patent: May 13, 2025Assignee: Cellphire, Inc.Inventors: Keith Andrew Moskowitz, Braden Carl Ishler, William Matthew Dickerson, Narendra Nath Tandon, Amber Nicole Lee, Stephen Edward Amos, Rafael Jorda, Michael Alexander Mathews
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Patent number: 12208122Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.Type: GrantFiled: April 24, 2024Date of Patent: January 28, 2025Assignee: Cellphire, IncInventors: Keith Andrew Moskowitz, Braden Carl Ishler, William Matthew Dickerson, Narendra Nath Tandon, Amber Nicole Lee, Glen Michael Fitzpatrick
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Publication number: 20240408141Abstract: Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.Type: ApplicationFiled: August 20, 2024Publication date: December 12, 2024Applicant: Cellphire, Inc.Inventors: Keith Andrew MOSKOWITZ, Braden Carl ISHLER, William Matthew DICKERSON, Narendra Nath TANDON, Amber Nicole LEE, Stephen Edward AMOS, Rafael JORDA, Michael Alexander MATHEWS
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Publication number: 20240277771Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.Type: ApplicationFiled: April 24, 2024Publication date: August 22, 2024Applicant: Cellphire, Inc.Inventors: Keith Andrew MOSKOWITZ, Braden Carl ISHLER, William Matthew DICKERSON, Narendra Nath TANDON, Amber Nicole LEE, Glen Michael FITZPATRICK
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Publication number: 20230285465Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.Type: ApplicationFiled: May 16, 2023Publication date: September 14, 2023Applicant: Cellphire, Inc.Inventors: Keith Andrew MOSKOWITZ, Braden Carl ISHLER, William Matthew DICKERSON, Narendra Nath Tandon, Amber Nicole LEE, Glen Michael FITZPATRICK
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Patent number: 11701388Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.Type: GrantFiled: August 14, 2020Date of Patent: July 18, 2023Assignee: Cellphire, Inc.Inventors: Keith Andrew Moskowitz, Braden Carl Ishler, William Matthew Dickerson, Narendra Nath Tandon, Amber Nicole Lee, Glen Michael Fitzpatrick
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Publication number: 20220273724Abstract: Provided herein are methods and compositions for treating a coagulopathy in a subject. Such methods can include administering to the subject in need thereof, for example because they have been administered an anticoagulant agent, an effective amount of a composition including platelets, or in illustrative embodiments platelet derivatives, and in further illustrative embodiments freeze-dried platelet derivatives (FDPDs). Various properties of exemplary embodiments of such methods and platelet derivatives used therein, as well as numerous additional aspects and embodiments are provided herein.Type: ApplicationFiled: February 17, 2022Publication date: September 1, 2022Applicant: CELLPHIRE INC.Inventors: Keith Andrew MOSKOWITZ, Braden Carl ISHLER, William Matthew DICKERSON, Narendra Nath TANDON, Amber Nicole LEE, Stephon Edward AMOS, Rafael JORDA, Michael Alexander MATHEWS
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Publication number: 20220168353Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject that is being administered or has been administered an antiplatelet agent, the method comprising: (a) determining that the subject has an abnormal result for evaluation of one or more clotting parameters; and (b) after (a), administering to the subject in need thereof an effective amount of a composition comprising platelets or platelet derivatives and an incubating agent comprising one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent.Type: ApplicationFiled: February 16, 2022Publication date: June 2, 2022Applicant: CELLPHIRE INC.Inventors: Keith Andrew MOSKOWITZ, Braden Carl ISHLER, William Matthew DICKERSON, Narendra Nath TANDON, Amber Nicole LEE, Stephon Edward AMOS, Rafael JORDA, Michael Alexander MATTHEWS
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Publication number: 20210308185Abstract: Provided herein are methods and compositions for treating acquired hemophilia with platelets and/or platelet derivatives. In some cases, the platelets and or platelet derivatives are loaded with an anti-fibrinolytic.Type: ApplicationFiled: February 3, 2021Publication date: October 7, 2021Inventors: Keith Andrew Moskowitz, Shan Xu, William Matthew Dickerson, Amber Nicole Lee, Braden Carl Ishler, Daniel Allen Sheik, Narendra Nath Tandon
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Publication number: 20210299179Abstract: Provided herein are methods and compositions for treating congenital hemophilia with platelets and/or platelet derivatives. In some cases, the platelets and or platelet derivatives are loaded with an anti-fibrinolytic.Type: ApplicationFiled: February 3, 2021Publication date: September 30, 2021Inventors: Keith Andrew Moskowitz, Shan Xu, William Matthew Dickerson, Amber Nicole Lee, Braden Carl Ishler, Daniel Allen Sheik, Narendra Nath Tandon
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Publication number: 20210046121Abstract: In some embodiments provided herein is a method of treating a coagulopathy in a subject, the method including administering to the subject in need thereof an effective amount of a composition including platelets or platelet derivatives and an incubating agent including one or more salts, a buffer, optionally a cryoprotectant, and optionally an organic solvent, wherein the subject has been treated or is being treated with an antiplatelet agent.Type: ApplicationFiled: August 14, 2020Publication date: February 18, 2021Inventors: Keith Andrew Moskowitz, Braden Carl Ishler, William Matthew Dickerson, Narendra Nath Tandon, Amber Nicole Lee
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Patent number: 7645592Abstract: The present invention describes antibodies generated against platelet membrane glycoprotein VI (GPVI), methods of producing the anti-GPVI antibodies, and the use of these antibodies as research, diagnostic and immunotherapeutic agents, in particular, as diagnostic and therapeutic agents for the detection and treatment of thrombosis and other vascular diseases.Type: GrantFiled: November 15, 2006Date of Patent: January 12, 2010Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Hisao Takizawa, Yutaka Matsumoto, Narendra Nath Tandon, Keiji Okuyama
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Patent number: 7611707Abstract: The present invention describes antibodies generated against platelet membrane glycoprotein VI-(GPVI), methods of producing the anti-GPVI antibodies, and the use of these antibodies as research and immunotherapeutic agents, in particular, as antithrombotic therapeutic agents.Type: GrantFiled: April 26, 2005Date of Patent: November 3, 2009Assignee: Otsuka Pharmaceutical Co., Ltd.Inventors: Narendra Nath Tandon, Yutaka Matsumoto, Hisao Takizawa, Keiji Okuyama
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Patent number: 6998469Abstract: The present invention comprises a method of purifying GPVI, GPVI peptides, cDNA and protein sequence, and methods for using GPVI and antibodies directed against GPVI.Type: GrantFiled: May 29, 2003Date of Patent: February 14, 2006Assignee: Otsuka America Pharmaceutical, Inc.Inventors: Narendra Nath Tandon, Bing Sun, Takashi Nakamura, Naomasa Yamamoto
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Publication number: 20040152628Abstract: The present invention comprises a method of purifying GPVI, GPVI peptides, cDNA and protein sequence, and methods for using GPVI and antibodies directed against GPVI.Type: ApplicationFiled: May 29, 2003Publication date: August 5, 2004Applicant: Otsuka America Pharmaceutical Inc.Inventors: Narendra Nath Tandon, Bing Sun, Takashi Nakamura, Naomasa Yamamoto
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Publication number: 20030186885Abstract: The present invention comprises a method of purifying GPVI, GPVI peptides, cDNA and protein sequence, and methods for using GPVI and antibodies directed against GPVI.Type: ApplicationFiled: May 29, 2003Publication date: October 2, 2003Applicant: Otsuka America Pharmaceutical Inc.Inventors: Narendra Nath Tandon, Bing Sun, Takashi Nakamura, Naomasa Yamamoto