Patents by Inventor Narendra Wajapeyee

Narendra Wajapeyee has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Insulin-like growth factor binding protein 7 for treatment of cancer
    Patent number: 9248163
    Abstract: Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
    Type: Grant
    Filed: December 2, 2013
    Date of Patent: February 2, 2016
    Assignee: University of Massachusetts
    Inventors: Michael Green, Narendra Wajapeyee
  • INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 FOR TREATMENT OF CANCER
    Publication number: 20140178339
    Abstract: Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
    Type: Application
    Filed: December 2, 2013
    Publication date: June 26, 2014
    Inventors: Michael Green, Narendra Wajapeyee
  • Insulin-like growth factor binding protein 7 for treatment of cancer
    Patent number: 8598135
    Abstract: Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
    Type: Grant
    Filed: October 7, 2011
    Date of Patent: December 3, 2013
    Assignee: University of Massachusetts
    Inventors: Michael Green, Narendra Wajapeyee
  • INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 FOR TREATMENT OF CANCER
    Publication number: 20120094925
    Abstract: Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
    Type: Application
    Filed: October 7, 2011
    Publication date: April 19, 2012
    Applicant: UNIVERSITY OF MASSACHUSETTS
    Inventors: Michael Green, Narendra Wajapeyee
  • Insulin-like growth factor binding protein 7 for treatment of cancer
    Patent number: 8034792
    Abstract: Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
    Type: Grant
    Filed: September 11, 2008
    Date of Patent: October 11, 2011
    Assignee: University of Massachusetts
    Inventors: Michael Green, Narendra Wajapeyee
  • RAS-MEDIATED EPIGENETIC SILENCING EFFECTORS AND USES THEREOF
    Publication number: 20100137411
    Abstract: The invention relates to methods for inhibiting gene silencing, methods for inhibiting cell proliferation, methods for inhibiting Ras mediated tumor growth, methods for screening for regulators of FAS expression, and methods for identifying inhibitors of Ras mediated tumor growth.
    Type: Application
    Filed: August 5, 2008
    Publication date: June 3, 2010
    Applicant: University of Massachusetts
    Inventors: Michael R. Green, Claude Gazin, Narendra Wajapeyee
  • INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 FOR TREATMENT OF CANCER
    Publication number: 20090142302
    Abstract: Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
    Type: Application
    Filed: September 11, 2008
    Publication date: June 4, 2009
    Inventors: Michael Green, Narendra Wajapeyee