Patents by Inventor Naresh Chintaman Dumbre

Naresh Chintaman Dumbre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives
    Patent number: 10752647
    Abstract: There is a need for a new antibiotic having a novel mechanism of action, which exhibits strong antibacterial activity not only against sensitive bacteria, but also against resistant bacteria thereof, and at the same time possess excellent solubility and safety profile amenable to human use. As a result of intensive research, the present inventors have found that N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives represented by general formula (I), a regioisomer, a stereoisomer, or a pharmaceutically acceptable salt thereof possess excellent solubility and safety profile for use in human for the treatment of bacterial infectious diseases.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: August 25, 2020
    Assignee: Daiichi Sankyo Company, Limited
    Inventors: Manoj Kumar Khera, Naresh Chintaman Dumbre, Pasha Khan
  • N-PHOSPHONOXYMETHL PRODRUGS OF HYDROXYALKYL THIADIAZOLE DERIVATIVES
    Publication number: 20200040019
    Abstract: There is a need for a new antibiotic having a novel mechanism of action, which exhibits strong antibacterial activity not only against sensitive bacteria, but also against resistant bacteria thereof, and at the same time possess excellent solubility and safety profile amenable to human use. As a result of intensive research, the present inventors have found that N-phosphonoxymethyl prodrugs of hydroxyalkyl thiadiazole derivatives represented by general formula (I), a regioisomer, a stereoisomer, or a pharmaceutically acceptable salt thereof possess excellent solubility and safety profile for use in human for the treatment of bacterial infectious diseases.
    Type: Application
    Filed: March 13, 2018
    Publication date: February 6, 2020
    Applicant: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Manoj Kumar Khera, Naresh Chintaman Dumbre, Pasha Khan