Patents by Inventor Narina Y. Stepanova

Narina Y. Stepanova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250256275
    Abstract: According to an embodiment, a sample collection system includes a sample collection device and an eluent delivery element. The sample collection devices includes a housing including an airflow path extending from a proximal end including an air inlet to a distal end; a piercing element arranged within the airflow path; and a sample collector including porous sample collection media arranged to occlude the airflow path. The eluent delivery element includes a reservoir containing an eluent; and a membrane disposed at a coupling end of the reservoir and sealing the reservoir, the coupling end being constructed to couple with the proximal end of the airflow path such that the piercing element pierces the membrane.
    Type: Application
    Filed: October 18, 2022
    Publication date: August 14, 2025
    Inventors: Audrey A. Sherman, Brett J. Sitter, Alan R. Dombrowski, Narina Y. Stepanova, Tonya D. Bonilla, Michael R. Berrigan, Laura R. Nereng
  • Publication number: 20240341627
    Abstract: A protected sample collection media for use in a sample collection device includes a piece of porous sample collection media having a first major side and an opposing second major side; and a protective sheath fully covering the first major side and the second major side. The protective sheath has a first portion and a second portion. The first portion is removable without removing the second portion. The second portion forms a tab constructed to be gripped by hand. The protected sample collection media may be part of a system including a sample collection device. The system may be provided as a kit including instructions for use of the kit.
    Type: Application
    Filed: July 20, 2022
    Publication date: October 17, 2024
    Inventors: Audrey A. Sherman, Alan R. Dombrowski, Michael R. Berrigan, Brett J. Sitter, Tonya D. Bonilla, Narina Y. Stepanova, Laura R. Nereng, Michael C. Wohl
  • Publication number: 20240341628
    Abstract: A sample collection device includes a housing including an exhalation portion and a coupling portion. The coupling portion can be coupled with/to a sample collection tube. An airflow path extends through the housing. The device further includes porous sample collection media partially disposed between within the housing and arranged to occlude the airflow path. The porous sample collection includes nonwoven material and may include polylactic acid, polypropylene, or a combination thereof. The housing can be a single piece, part, or component, or can be multiple pieces, parts, components, or portions. In an embodiment of a two-piece housing, the first part includes an exhalation piece (e.g., a mouthpiece or nosepiece) and the second part includes a coupling end constructed for coupling with a sample collection tube.
    Type: Application
    Filed: July 20, 2022
    Publication date: October 17, 2024
    Inventors: Audrey A. Sherman, Alan R. Dombrowski, Brett J. Sitter, Michael R. Berrigan, Tonya D. Bonilla, Narina Y. Stepanova, Laura R. Nereng
  • Publication number: 20240285263
    Abstract: A sample collection system includes a housing comprising a first part and a second part, the first and second parts being movable relative to one another; porous sample collection media disposed along an airflow path in the first part; and an assay disposed on the second part and constructed to receive a sample captured by the porous sample collection media. The first and second parts are rotatably movable relative to one another. Moving the first and second parts relative to one another aligns the porous sample collection media with at least a portion of the assay. The assay may be a lateral flow assay or a vertical flow assay. The media is constructed to collect a sample from exhalation airflow. A collected sample may be eluted from the media onto the assay using a liquid.
    Type: Application
    Filed: May 24, 2022
    Publication date: August 29, 2024
    Inventors: Michael R. Berrigan, Alan R. Dombrowski, Laura R. Nereng, Audrey A. Sherman, Brett J. Sitter, Narina Y. Stepanova
  • Publication number: 20240277321
    Abstract: A sample collection device includes a planar sheet of material having opposing edges and a first major surface and an opposing second major surface, the planar sheet of material having at least two fold lines. A porous sample collection media has at least three edges and opposing major surfaces, at least one edge is fixed to the first major surface of the planar sheet of material. The planar sheet of material is configured to form an airflow channel by fixing the opposing edges together, the airflow channel extends from a mouthpiece end to an air outlet end. The porous sample collection media substantially occludes the airflow channel between the mouthpiece end and the air outlet end.
    Type: Application
    Filed: May 18, 2022
    Publication date: August 22, 2024
    Inventors: Michael R. Berrigan, Alan R. Dombrowski, Laura R. Nereng, Audrey A. Sherman, Brett J. Sitter, Narina Y. Stepanova
  • Publication number: 20240261780
    Abstract: A sample collection system includes a housing comprising a first part and a second part, the first and second parts being movable relative to one another; porous sample collection media disposed along an airflow path in the first part; and an assay disposed on the second part and constructed to receive a sample captured by the porous sample collection media. The first and second parts may be slidably movable relative to one another. The first and second parts may be rotatably movable relative to one another. Moving the first and second parts relative to one another aligns the porous sample collection media with at least a portion of the assay. The assay may be a lateral flow assay or a vertical flow assay. The media is constructed to collect a sample from exhalation airflow. A collected sample may be eluted from the media onto the assay using a liquid.
    Type: Application
    Filed: May 19, 2022
    Publication date: August 8, 2024
    Inventors: Michael R. Berrigan, Alan R. Dombrowski, Laura R. Nereng, Audrey A. Sherman, Brett J. Sitter, Narina Y. Stepanova, Michael C. Wohl
  • Publication number: 20240237971
    Abstract: A sample collection device includes a housing extending from a mouthpiece end to an air outlet end, the housing defining an airflow channel from the mouthpiece end to the air outlet end, the mouthpiece end configured to receive an exhalation airflow. A porous sample collection media is fixed within the housing and along the airflow channel. A mouthpiece end cap is replaceably coupled to the mouthpiece end and an air outlet end cap is replaceably coupled to the air outlet end.
    Type: Application
    Filed: February 11, 2022
    Publication date: July 18, 2024
    Inventors: Michael R. Berrigan, Tonya D. Bonilla, Alan R. Dombrowski, Laura R. Nereng, Audrey A. Sherman, Brett J. Sitter, Narina Y. Stepanova, Michael C. Wohl
  • Publication number: 20240188939
    Abstract: The present disclosure relates to sample collection devices and sample collection and testing devices. The devices described herein includes a housing defining a fluid channel from a first portion to a second portion. The devices further include a porous sample collection media disposed within the housing and in fluid communication with the fluid channel. The devices further include a fluid inlet port disposed in fluid communication with the porous sample collection media. The fluid inlet port is configured to direct a test fluid onto the porous sample collection media. The sample collection device further includes an assay configured to receive a fluid that was incident on the porous sample collection media (and eluent) and test that eluent for the presence (or absence) of a pathogen or virus.
    Type: Application
    Filed: February 11, 2022
    Publication date: June 13, 2024
    Inventors: Audrey A. Sherman, Brett J. Sitter, Alan R. Dombrowski, Laura R. Nereng, Michael R. Berrigan, Narina Y. Stepanova, Adam S. Troness, Michael C. Wohl
  • Publication number: 20240188562
    Abstract: A disinfecting composition useful for care and protection of interior automotive surfaces. The composition includes a silicone package, typically including a silicone fluid, and a disinfectant, typically a quaternary ammonium compound.
    Type: Application
    Filed: March 24, 2022
    Publication date: June 13, 2024
    Inventors: DanLi WANG, Brian P. DUTKIEWICZ, Narina Y. STEPANOVA, Briklyn M. WUICH, Bathsheba E.F. Chong Conklin, Linda J. Murray, Judd D. Olson
  • Publication number: 20240180443
    Abstract: The present disclosure provides a sample collection device. The sample collection device includes a housing defining a fluid channel from a first portion to a second portion. The sample collection device further includes a porous sample collection media disposed within the housing and in fluid communication with the fluid channel. The sample collection device further includes a fluid inlet port disposed in fluid communication with the porous sample collection media. The fluid inlet port is configured to direct a test fluid onto the porous sample collection media. The sample collection device further includes an assay configured to receive a fluid that was incident on the porous sample collection media.
    Type: Application
    Filed: March 29, 2022
    Publication date: June 6, 2024
    Inventors: Audrey A. Sherman, Brett J. Sitter, Alan R. Dombrowski, Laura R. Nereng, Michael R. Berrigan, Narina Y. Stepanova
  • Publication number: 20240115246
    Abstract: A sample collection device including a housing extending from a mouthpiece portion to an air outlet portion. The housing defines an airflow channel from the mouthpiece portion to the air outlet portion. The mouthpiece portion is configured to receive an h exhalation airflow. A porous sample collection media is disposed within the housing and along the airflow channel. A fluid inlet port defines an aperture through the housing and is adjacent to the porous sample collection media. The fluid inlet port is configured to direct id onto the porous sample collection media. A metered fluid dose element is attached to the fluid inlet port. The metered fluid dose element is configured to dispense a metered volume of fluid into the fluid inlet port.
    Type: Application
    Filed: February 11, 2022
    Publication date: April 11, 2024
    Inventors: Michael R. Berrigan, Alan R. Dombrowski, Laura R. Nereng, Audrey A. Sherman, Brett J. Sitter, Narina Y. Stepanova, Michael C. Wohl
  • Publication number: 20240114905
    Abstract: The composition includes an antimicrobial monomer represented by formula CH2?C(R1)—C(O)—O-Q-N+(R)2CnH2n+1(X—), a non-fluorinated crosslinking monomer having at least two acrylate groups, methacrylate groups, or a combination thereof, a polar monomer having at least one of acrylic acid, methacrylic acid, or a carboxylate salt thereof, and a nonpolar monomer represented by formula CH2?C(R1)—C(O)—O—R2. The antimicrobial monomer, the non-fluorinated crosslinking monomer, the polar monomer, and the nonpolar monomer together account for greater than 95 percent by weight, based on the total weight of the composition. The article includes a film having a plurality of pendent groups represented by formula —C(O)—O-Q-N+(R)2CnH2n+1(X—) covalently bonded in a crosslinked non-fluorinated acrylic network. A method of making an article is also described.
    Type: Application
    Filed: January 28, 2022
    Publication date: April 11, 2024
    Inventors: Mahfuza B. Ali, Jodi L. Connell, Judith M. Invie, Narina Y. Stepanova, Bryan V. Hunt, Timothy J. Hebrink
  • Publication number: 20230049504
    Abstract: A transfer article includes an acrylate layer releasable from a release layer including a metal layer, a metal oxide layer, or a doped semiconductor layer at a release value of from 2 to 50 grams/inch (0.8 to 20 g/cm). A functional layer overlies the acrylate layer, wherein the functional layer includes at least one layer of a functional material selected to provide at least one of a therapeutic, aesthetic or cosmetic benefit on a dental appliance in a mouth of a patient, and wherein the transfer article has a thickness of less than 3 micrometers. A pattern of a transfer material is on a major surface of the functional layer, wherein the transfer material includes an adhesion modifying material chosen from release materials and adhesives.
    Type: Application
    Filed: December 29, 2020
    Publication date: February 16, 2023
    Inventors: Bhaskar V. Velamakanni, Kevin W. Gotrik, Kevin T. Reddy, Scott J. Jones, Matthew S. Stay, Matthew R.D. Smith, Yizhong Wang, Mikhail L. Pekurovsky, Narina Y. Stepanova
  • Patent number: 11571490
    Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer and a substrate having a nanostructured surface. The nanostructured surface is coated with a metal oxide layer and the metal oxide layer includes a metal oxide.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: February 7, 2023
    Assignee: 3M INNOVATIVE PROPERTIES COMPANY
    Inventors: Ta-Hua Yu, Junkang Jacob Liu, Narina Y. Stepanova, Badri Veeraraghavan, Moses M. David
  • Publication number: 20220110906
    Abstract: A dental appliance includes a polymeric shell with an arrangement of one or more cavities configured to receive one or more teeth, and the polymeric shell includes an antimicrobial lipid, such as monolaurin, and optionally an enhancer.
    Type: Application
    Filed: December 30, 2019
    Publication date: April 14, 2022
    Inventors: Ta-Hua Yu, Timothy J. Hebrink, Yongshang Lu, Karl J.L. Geisler, Narina Y. Stepanova, Mary E. Johansen, Jay M. Jennen, Bhaskar V. Velamakanni, David P. Siglin, Mark T. Gibson, Troy J. Anderson
  • Publication number: 20210251724
    Abstract: A dental appliance includes a polymeric shell with a first major surface having a plurality of cavities for receiving one or more teeth, and a layer of a metal oxide MOx on the first major surface.
    Type: Application
    Filed: June 10, 2019
    Publication date: August 19, 2021
    Inventors: Bhaskar V. Velamakanni, Ta-Hua Yu, Daniel J. Skamser, Narina Y. Stepanova, Mitchell A. Hirsch, Junkang J. Liu, Carola A. Carrera Vidal
  • Patent number: 10639395
    Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate having two opposing major surfaces, wherein one opposing major surface is a nanostructured surface; a metal oxide layer, wherein the nanostructured surface is coated with the metal oxide layer and the metal oxide layer comprises a metal oxide; and a metal layer overlaying the metal oxide layer.
    Type: Grant
    Filed: November 10, 2016
    Date of Patent: May 5, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Ta-Hua Yu, Döne Demirgöz, Junkang J. Liu, Badri Veeraraghavan, Narina Y. Stepanova
  • Patent number: 10617784
    Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate overlaying the occlusive layer, wherein the substrate having two opposing major surfaces; a metal oxide layer overlaying the substrate, wherein the metal oxide layer comprises a metal oxide and wherein the metal oxide layer comprises less than 40 wt. % non-oxidized metal; and a metal layer overlaying the metal oxide layer.
    Type: Grant
    Filed: November 3, 2016
    Date of Patent: April 14, 2020
    Assignee: 3M Innovative Properties Company
    Inventors: Ta-Hua Yu, Döne Demirgöz, Junkang J. Liu, Badri Veeraraghavan, Narina Y. Stepanova
  • Publication number: 20190275191
    Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate overlaying the occlusive layer, wherein the substrate having two opposing major surfaces; a metal oxide layer overlaying one opposing major surface of the substrate, wherein the metal oxide layer comprises a metal oxide; and a metal layer overlaying the other opposing major surface of the substrate; wherein the substrate is between the metal oxide layer and the metal layer; and wherein electric potential of the metal oxide layer is at least 0.454V more than electric potential of the metal layer.
    Type: Application
    Filed: October 5, 2017
    Publication date: September 12, 2019
    Inventors: Junkang Jacob Liu, Ta-Hua Yu, Amy K. McNulty, Narina Y. Stepanova, Badri Veeraraghavan, Eric J. Olson, Matthew T. Scholz, Ranjani V. Parthasarathy, Kevin D. Hagen
  • Publication number: 20180353638
    Abstract: An article having anti-microbial effect is provided. The article includes an occlusive layer; a substrate overlaying the occlusive layer, wherein the substrate having two opposing major surfaces; a metal oxide layer overlaying the substrate, wherein the metal oxide layer comprises a metal oxide and wherein the metal oxide layer comprises less than 40 wt. % non-oxidized metal; and a metal layer overlaying the metal oxide layer.
    Type: Application
    Filed: November 3, 2016
    Publication date: December 13, 2018
    Inventors: Ta-Hua Yu, Döne Demirgöz, Junkang J. Liu, Badri Veeraraghavan, Narina Y. Stepanova