Patents by Inventor Nasir MALIK

Nasir MALIK has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Engineering neural stem cells using homologous recombination
    Patent number: 9951353
    Abstract: Described herein are recombinant polynucleotide-binding polypeptides, recombinant fusion proteins made with the described polynucleotide-binding polypeptides, methods of using the described recombinant polynucleotide-binding polypeptides and recombinant fusion proteins to modify genomic DNA of cells and, in some embodiments, create recombinant cells. Methods are also provided herein for genetically modifying a neuronal stem cell. Methods are also provided for treating a neurological disorder in a subject that include the administration of genetically modified neuronal stem cells produced by the methods disclosed herein.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: April 24, 2018
    Assignee: The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Mahendra S. Rao, Nasir Malik, Raymond Funahashi, Jizhong Zou
  • ENGINEERING NEURAL STEM CELLS USING HOMOLOGOUS RECOMBINATION
    Publication number: 20160264999
    Abstract: Described herein are recombinant polynucleotide-binding polypeptides, recombinant fusion proteins made with the described polynucleotide-binding polypeptides, methods of using the described recombinant polynucleotide-binding polypeptides and recombinant fusion proteins to modify genomic DNA of cells and, in some embodiments, create recombinant cells. Methods are also provided herein for genetically modifying a neuronal stem cell. Methods are also provided for treating a neurological disorder in a subject that include the administration of genetically modified neuronal stem cells produced by the methods disclosed herein.
    Type: Application
    Filed: November 14, 2014
    Publication date: September 15, 2016
    Inventors: Mahendra S. RAO, Nasir MALIK, Raymond FUNAHASHI, Jizhong ZOU