Abstract: Disclosed is a medical imaging conversion method, automatically converting: at least one or more real x-ray images of a patient, including at least a first anatomical structure of the patient and a second anatomical structure of the patient, into at least one digitally reconstructed radiograph (DRR) of the patient representing the first anatomical structure without representing the second anatomical structure, by a single operation using either one convolutional neural network (CNN) or a group of convolutional neural networks (CNN) which is preliminarily trained to, both or simultaneously: differentiate the first anatomical structure from the second anatomical structure, and convert a real x-ray image into at least one digitally reconstructed radiograph (DRR).