Abstract: An adaptive optics system comprises a spatial light modulator, a beamsplitter, a pixelated spatial phase shifter, a beam combiner, an imaging device, and a processor. The spatial light modulator can modulate an incoming beam with an aberrated wavefront. The beamsplitter can receive the modulated beam and divide the modulated beam into a first beam and a second beam. The pixelated spatial phase shifter can spatially phase shift the second beam by at least two phases. The beam combiner can interfere the spatially phase shifted second beam with the first beam to form at least two interferograms on the imaging device, which can capture an image of the at least two interferograms in a single frame. The processor can determine the aberrated wavefront based on the at least two interferograms and provide one or more control signals to the spatial light modulator to mitigate aberrations in the aberrated wavefront.