Patents by Inventor Natalia Alexeevna Sanina

Natalia Alexeevna Sanina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water-soluble binuclear nitrosyl iron complexes with natural aliphatic thiolyls possessing cytotoxic, apoptotic and no-donor activity
    Patent number: 8067628
    Abstract: The present invention relates to water-soluble binuclear cationic nitrosyl iron complexes with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4, wherein R is sulfur-containing aliphatic ligands of natural origin, preferably, cystamine or penicillamine, to a method for the preparation thereof, to use thereof as an anticancer agent, to an apoptosis inducer, to a pharmaceutical composition comprising said complexes in an effective amount, and to a kit useful for the treatment of cancer diseases.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: November 29, 2011
    Assignee: Institute of Problems of Chemcial Physics RAS (IPCP RAS)
    Inventors: Natalia Alexeevna Sanina, Konstantin Alexandrovich Lysenko, Olga Stepanovna Zhukova, Tatyana Nikolaevna Rudneva, Nina Sergeevna Emelianova, Sergei Mikhailovich Aldoshin
  • WATER-SOLUBLE BINUCLEAR NITROSYL IRON COMPLEXES WITH NATURAL ALIPHATIC THIOLYLS POSSESSING CYTOTOXIC, APOPTOTIC AND NO-DONOR ACTIVITY
    Publication number: 20100190850
    Abstract: The present invention relates to water-soluble binuclear cationic nitrosyl iron complexes with natural aliphatic thiolyls of general formula [Fe2(SR)2(NO)4]SO4, wherein R is sulfur-containing aliphatic ligands of natural origin, preferably, cystamine or penicillamine, to a method for the preparation thereof, to use thereof as an anticancer agent, to an apoptosis inducer, to a pharmaceutical composition comprising said complexes in an effective amount, and to a kit useful for the treatment of cancer diseases.
    Type: Application
    Filed: June 2, 2008
    Publication date: July 29, 2010
    Applicant: Institute Of Problems of Chemical Physics RAS (IPCP RAS)
    Inventors: Natalia Alexeevna Sanina, Konstantin Alexandrovich Lysenko, Olga Stepanovna Zhukova, Tatyana Nikolaevna Rudneva, Nina Sergeevna Emelianova, Sergei Mikhailovich Aldoshin