Patents by Inventor Natalia B. Dyatkina

Natalia B. Dyatkina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7629328
    Abstract: Disclosed are methods for treating hepatitis C viral infections using deaza-purine compounds of Formula I: wherein W, W1, W2, Y, R1, Z, Y? and R are as defined herein.
    Type: Grant
    Filed: September 8, 2008
    Date of Patent: December 8, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Christopher D. Roberts, Jesse Keicher, Natalia B. Dyatkina
  • Patent number: 7629320
    Abstract: Disclosed are ?-D-ribofuranosyl-pyrazolo[3,4-d]pyrimidine compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Representative compounds include those having the general formula.
    Type: Grant
    Filed: May 19, 2008
    Date of Patent: December 8, 2009
    Assignee: SmithKline Beecham Corporation
    Inventors: Natalia B. Dyatkina, Christopher D. Roberts
  • Publication number: 20090036399
    Abstract: Disclosed are methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein W, W1, W2, Y, R1, Z, Y? and R are as defined herein.
    Type: Application
    Filed: September 8, 2008
    Publication date: February 5, 2009
    Inventors: Christopher D. Roberts, Jesse Keicher, Natalia B. Dyatkina
  • Publication number: 20080249060
    Abstract: Disclosed are compounds, compositions and methods for treating hepatitis C virus infections.
    Type: Application
    Filed: May 19, 2008
    Publication date: October 9, 2008
    Inventors: Christopher Don Roberts, Natalia B. Dyatkina
  • Patent number: 7432248
    Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein W, W1, W2, Y, R1, Z, Y? and R are as defined herein.
    Type: Grant
    Filed: July 24, 2006
    Date of Patent: October 7, 2008
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher D. Roberts, Jesse Keicher, Natalia B. Dyatkina
  • Patent number: 7425547
    Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula IB as follows: and pharmaceutically acceptable prodrugs and salts thereof, where R, R1, R13, R14, W, W2, W3, Y and Z are as defined herein.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: September 16, 2008
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher Don Roberts, Natalia B. Dyatkina
  • Patent number: 7414031
    Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
    Type: Grant
    Filed: November 15, 2005
    Date of Patent: August 19, 2008
    Assignee: Genelabs Technologies, Inc.
    Inventors: Jesse D. Keicher, Christopher D. Roberts, Natalia B. Dyatkina
  • Patent number: 7405204
    Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a Flaviviridae family virus, such as hepatitis C virus.
    Type: Grant
    Filed: April 25, 2006
    Date of Patent: July 29, 2008
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher D. Roberts, Ronald Conrad Griffith, Natalia B. Dyatkina, Marija Prhavc
  • Patent number: 7244713
    Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein, T, Y, W, W1 and W2 are as defined herein.
    Type: Grant
    Filed: October 21, 2004
    Date of Patent: July 17, 2007
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher D. Roberts, Jesse D. Keicher, Natalia B. Dyatkina
  • Patent number: 7169918
    Abstract: Disclosed are methods and intermediates for the preparation of 7-(2?-R1-substituted-?-D-ribofuranosyl)-4-amino-5-(optionally substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine compounds. These compounds are useful in treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such 7-(2?-substituted-?-D-ribofuranosyl)-4-amino-5-(optionally substituted ethyn-1-yl)-pyrrolo[2,3-d]pyrimidine compounds are represented by Formula I as follows: wherein, each of R1, R2, and R3 are as defined herein.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: January 30, 2007
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher D. Roberts, Jesse D. Keicher, Natalia B. Dyatkina
  • Patent number: 7157434
    Abstract: Disclosed are compounds, compositions and methods for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus. Such compounds are represented by Formula I as follows: wherein, Y, W, W1 and W2 are as defined herein.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: January 2, 2007
    Assignee: Genelabs Technologies, Inc.
    Inventors: Jesse D. Keicher, Christopher D. Roberts, Natalia B. Dyatkina
  • Patent number: 7094768
    Abstract: Disclosed are 6-hydroxyamino- or a 6-alkoxyamino-7-deazapurine-ribofuranose derivatives, salts, pharmaceutical compositions, and methods of use thereof for treating viral infections caused by a flaviviridae family virus, such as hepatitis C virus.
    Type: Grant
    Filed: April 8, 2004
    Date of Patent: August 22, 2006
    Assignee: Genelabs Technologies, Inc.
    Inventors: Christopher D. Roberts, Jesse Keicher, Natalia B. Dyatkina
  • Patent number: 7064218
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
    Type: Grant
    Filed: December 24, 2002
    Date of Patent: June 20, 2006
    Assignee: Genelabs Technologies, Inc.
    Inventors: Natalia B. Dyatkina, Dong-Fang Shi, Christopher Don Roberts, Mark Douglas Velligan, Sebastian Johannes Reinhard Liehr, Janos Botyanszki, Wentao Zhang, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Patent number: 6906103
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
    Type: Grant
    Filed: October 23, 2002
    Date of Patent: June 14, 2005
    Assignee: Genelabs Technologies, Inc.
    Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Patent number: 6849713
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity. The compounds are of Formula (I): Pharmaceutical compositions containing these compounds, methods of making and methods for using these compounds are also provided.
    Type: Grant
    Filed: June 26, 2001
    Date of Patent: February 1, 2005
    Assignee: Genelabs Technologies, Inc.
    Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Publication number: 20040147464
    Abstract: Disclosed are compounds, compositions and methods for treating hepatitis C virus infections.
    Type: Application
    Filed: September 30, 2003
    Publication date: July 29, 2004
    Applicant: Genelabs Technologies, Inc.
    Inventors: Christopher Don Roberts, Natalia B. Dyatkina
  • Publication number: 20040063658
    Abstract: Disclosed are compounds, compositions and methods for treating hepatitis C virus infections.
    Type: Application
    Filed: May 6, 2003
    Publication date: April 1, 2004
    Inventors: Christopher Don Roberts, Natalia B. Dyatkina, Jesse D. Keicher, Sebastian Johannes Reinhard Liehr, Eric Jason Hanson
  • Publication number: 20030212113
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity.
    Type: Application
    Filed: December 24, 2002
    Publication date: November 13, 2003
    Inventors: Natalia B. Dyatkina, Dong-Fang Shi, Christopher Don Roberts, Mark Douglas Velligan, Sebastian Johannes Reinhard Liehr, Janos Botyanszki, Wentao Zhang, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Publication number: 20030119749
    Abstract: The present invention provides novel compounds possessing one or more of the following activities: antibacterial, antifungal and antitumor activity.
    Type: Application
    Filed: October 23, 2002
    Publication date: June 26, 2003
    Inventors: Wentao Zhang, Sebastian Johannes Reinhard Liehr, Mark Douglas Velligan, Natalia B. Dyatkina, Janos Botyanszki, Dong-Fang Shi, Christopher Don Roberts, Alexander Khorlin, Peter Harold Nelson, Joseph Martin Muchowski
  • Publication number: 20020198254
    Abstract: This invention is directed to novel antibacterial/antifungal/antiparasitic agents of Formula (I): 1
    Type: Application
    Filed: December 27, 2001
    Publication date: December 26, 2002
    Inventors: Mark D. Velligan, Alexander Khorlin, Natalia B. Dyatkina, Dong-Fang Shi, Janos Botyanszki, Sebastian Liehr