Patents by Inventor Natalia LÓPEZ

Natalia LÓPEZ has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SINGLE DOMAIN VHH ANTIBODIES AGAINST SARS-COV-2 VIRUS
    Publication number: 20240067705
    Abstract: The invention provides a set of novel Single domain VHH antibodies against SARS-CoV-2 (SEQ ID N? 1-6) and their use to detect and neutralize the wild type virus.
    Type: Application
    Filed: November 15, 2022
    Publication date: February 29, 2024
    Inventors: Alejandro ROJAS, Guillermo VALENZUELA, Ronald JARA, Johanna HIMELREICHS, Constanza SALINAS, Teresa PINTO, Natalia LÓPEZ, Yorka CHEUQUEMILLA, Alexei CUEVAS, Zaray MIRANDA, Benjamín UBERTI, Ananda MULLER
  • ONE-STEP FAST GRADIENT METHOD FOR NANOANTIBODY GENERATION
    Publication number: 20230324403
    Abstract: One-step rapid gradient method for rapid generation of nanoantibodies (HHV) against any antigen. Where the method comprises the separation of nanoantibodies against a specific antigen from a nanoantibody expression library through the following steps: (a) binding the antigen of interest to beads made of protein-binding polymers (b) incubating the microorganisms of the expression library with the pearls of stage (a), (c) placing the beads of step (b) in a tube with an inert medium with a density greater than or equal to 1 g/mL and centrifuge for 45 s to 2 minutes at a rate between 150 and 250 g; d) discarding the upper fraction and supernatant with the free microorganisms, and obtain the beads with the linked microorganisms, which correspond to those that express HHV that recognizes the antigen.
    Type: Application
    Filed: May 14, 2021
    Publication date: October 12, 2023
    Inventors: Alejandro ROJAS, Guillermo VALENZUELA, Ronald JARA, Johanna HIMELREICHS, Constanza SALINAS, Teresa PINTO, Natalia LÓPEZ, Yorka CHEUQUEMILLA, Alexei CUEVAS, Zaray MIRANDA, Benjamín UBERTI, Ananda MULLER
  • IMMUNOGENIC FORMULATIONS FOR TREATING CANCER
    Publication number: 20220152167
    Abstract: Aspects of the present disclosure generally relate to immunotherapy, cancer vaccines and the treatment of cancer diseases. By way of example, the present disclosure relates to novel combined with an immunologically effective amount of adjuvant, for treating cancer in a subject methods of generating such formulations, and methods of use thereof.
    Type: Application
    Filed: March 5, 2020
    Publication date: May 19, 2022
    Inventors: Flavio Andres SALAZAR ONFRAY, Cristian Javier PEREDA RAMOS, Mercedes Natalia LOPEZ NITSCHE, Maria Alejandra GLEISNER MUNOZ, Andres TITTARELLI, Fermin GONZALEZ, Fabian TEMPIO, Marisol BRIONES
  • Ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related diseases
    Patent number: 9694059
    Abstract: The present invention relates to an ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related diseases. At the same time, it is related to a cellular composition that contributes to stimulate the activated antigen-presenting cells to induce a specific immune response against tumors in patients with cancer or other pathologies involving immune responses.
    Type: Grant
    Filed: May 1, 2013
    Date of Patent: July 4, 2017
    Assignee: Universidad de Chile
    Inventors: Flavio Andres Salazar Onfray, Mercedes Natalia Lopez Nitsche, Cristian Javier Pereda Ramos, Raquel Elvira Aguilera Insunza, Alejandro Felipe Escobar Alvarez
  • EX VIVO, FAST AND EFFICIENT PROCESS TO OBTAIN ACTIVATED ANTIGEN-PRESENTING CELLS THAT ARE USEFUL FOR THERAPIES AGAINST CANCER AND IMMUNE SYSTEM-RELATED DISEASES
    Publication number: 20100303868
    Abstract: The present invention relates to an ex vivo, fast and efficient process to obtain activated antigen-presenting cells that are useful for therapies against cancer and immune system-related diseases. At the same time, it is related to a cellular composition that contributes to stimulate the activated antigen-presenting cells to induce a specific immune response against tumors in patients with cancer or other pathologies involving immune responses.
    Type: Application
    Filed: September 26, 2008
    Publication date: December 2, 2010
    Applicants: UNIVERSIDAD DE CHILE, ONCOBIOMED
    Inventors: Flavio Andrés Salazar Onfray, Mercedes Natalia López Nitsche, Cristián Javier Pereda Ramos, Raquel Elvira Aguilera Insunza, Alejandro Felipe Escobar Álvarez