Patents by Inventor Natalia Lomovskaya

Natalia Lomovskaya has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing doxorubicin
    Patent number: 6210930
    Abstract: The present invention is directed to a process for improving daunorubicin and doxorubicin production by means of a recombinant microorganism in which a gene of daunorubicin metabolism is mutated. The mutated gene is preferably dnrU and/or dnrX.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: April 3, 2001
    Assignee: Pharmacia & Upjohn, S.P.A.
    Inventors: Silvia Filippini, Natalia Lomovskaya, Leonid Fonstein, Anna Luisa Colombo, C. Richard Hutchinson, Sharee L. Otten, Umberto Breme
  • Process for preparing daunorubicin and doxorubicin
    Patent number: 5989869
    Abstract: The present invention is directed to a process for improving daunorubicin and doxorubicin production by means of a recombinant microorganism in which a gene of daunorubicin metabolism involved in the glycosylation of daunorubicin to acid-sensitive, baumycin-like compounds is inactivated.
    Type: Grant
    Filed: March 6, 1997
    Date of Patent: November 23, 1999
    Assignee: Pharmacia & Upjohn S.p.A.
    Inventors: Silvia Filippini, Natalia Lomovskaya, Leonid Fonstein, Anna Luisa Colombo, C. Richard Hutchinson