Patents by Inventor Natalia Pavlovna Zakataeva

Natalia Pavlovna Zakataeva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Novel Gene and Method for Producing L-Amino Acids
    Publication number: 20160289716
    Abstract: The present invention describes a bacterium which has an ability to produce an amino acid and in which the rhtC gene encoding a protein having an enhanced activity of imparting L-threonine resistance to a bacterium expressing the protein. Preferably, the bacterium further includes an rhtB gene encoding for a protein having an enhanced activity of imparting to a bacterium L-homoserine resistance expressing the protein. The present invention also describes a method of cultivating the bacterium in a culture medium to produce and accumulate amino acids in the medium, and the amino acid is recovered from the medium.
    Type: Application
    Filed: June 17, 2016
    Publication date: October 6, 2016
    Applicant: AJINOMOTO CO., INC.
    Inventors: Vitaliy Arkadyevich Livshits, Natalia Pavlovna Zakataeva, Vladimir Veniaminovich Aleshin, Alla Valentinovna Belareva, Irina Lyvovna Tokhmakova
  • Method for producing an amino acid using a bacterium overexpressing an rhtC gene
    Patent number: 9394346
    Abstract: The present invention describes a bacterium which has an ability to produce an amino acid and in which the rhtC gene encoding a protein having an enhanced activity of imparting L-threonine resistance to a bacterium expressing the protein. Preferably, the bacterium further includes an rhtB gene encoding for a protein having an enhanced activity of imparting to a bacterium L-homoserine resistance expressing the protein. The present invention also describes a method of cultivating the bacterium in a culture medium to produce and accumulate amino acids in the medium, and the amino acid is recovered from the medium.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: July 19, 2016
    Assignee: AJINOMOTO CO., INC.
    Inventors: Vitaliy Arkadyevich Livshits, Natalia Pavlovna Zakataeva, Vladimir Veniaminovich Aleshin, Alla Valentinovna Belareva, Irina Lyvovna Tokhmakova
  • Method for producing purine nucleosides and nucleotides by fermentation using bacterium belonging to the genus or
    Patent number: 9012182
    Abstract: Methods for producing purine nucleosides, and purine nucleotides, such as inosine and 5?-inosinic acid are provided which include using a bacterium belonging to the genus Bacillus or to the genus Escherichia wherein the purine nucleoside productivity of said bacterium is enhanced by increasing an activity of the YdhL protein. Also disclosed is the amino acid sequence of the YdhL protein from Bacillus amyloliquefaciens and the gene encoding it.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: April 21, 2015
    Assignee: Ajinomoto Co., Inc.
    Inventors: Natalia Pavlovna Zakataeva, Vitaly Arkadievich Livshits, Sergey Viktorovich Gronsky, Ekaterina Aleksandrovna Kutukova, Anna Evgenievna Novikova, Yury Ivanovich Kozlov
  • Method for producing purine nucleosides and nucleotides by fermentation using a bacterium belonging to the genus or
    Patent number: 8034767
    Abstract: A method is provided for producing a purine nucleoside, such as inosine and guanosine, and a method for producing a 5?-purine nucleotide such as 5?-inosinic acid or 5?-guanylic acid, using a bacterium belonging to the either genus Escherichia or genus Bacillus, wherein purine nucleoside productivity of said bacterium is enhanced by enhancing an activity of a protein encoded by the yeaS (leuE) gene.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: October 11, 2011
    Assignee: Ajinomoto Co., Inc.
    Inventors: Ekaterina Aleksandrovna Kutukova, Natalia Pavlovna Zakataeva, Vitaly Arkadievich Livshits
  • METHOD FOR PRODUCING PURINE NUCLEOSIDES AND NUCLEOTIDES BY FERMENTATION USING A BACTERIUM BELONGING TO THE GENUS ESCHERICHIA OR BACILLUS
    Publication number: 20090298127
    Abstract: A method is provided for producing a purine nucleoside, such as inosine and guanosine, and a method for producing a 5?-purine nucleotide such as 5?-inosinic acid or 5?-guanylic acid, using a bacterium belonging to the either genus Escherichia or genus Bacillus, wherein purine nucleoside productivity of said bacterium is enhanced by enhancing an activity of a protein encoded by the yeaS (leuE) gene.
    Type: Application
    Filed: June 2, 2009
    Publication date: December 3, 2009
    Inventors: EKATERINA ALEKSANDROVNA KUTUKOVA, NATALIA PAVLOVNA ZAKATAEVA, VITALY ARKADIEVICH LIVSHITS
  • Method for producing an L-amino acid by enhancing expression of the yfiK gene in an bacterium
    Patent number: 7527950
    Abstract: A bacterium belonging to the genus Escherichia which has an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing expression of the yfiK gene is described. A method for producing the L-amino acid using the bacterium is also described.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: May 5, 2009
    Assignee: Ajinomoto Co., Inc.
    Inventors: Vitaliy Arkadievich Livshits, Natalia Pavlovna Zakataeva, Kazuo Nakanishi, Vladimir Veniaminovich Aleshin, Petr Vladimirovich Troshin, Irina Lyvovna Tokhmakova
  • Method for producing an L-amino acid by enhancing expression of the gene in an bacterium
    Patent number: 7524656
    Abstract: A bacterium belonging to the genus Escherichia which has an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing expression of the yggA gene is described. A method for producing the L-amino acid using the bacterium is also described.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: April 28, 2009
    Assignee: Ajinomoto Co., Inc.
    Inventors: Vitaliy Arkadievich Livshits, Natalia Pavlovna Zakataeva, Kazuo Nakanishi, Vladimir Veniaminovich Aleshin, Petr Vladimirovich Troshin, Irina Lyvovna Tokhmakova
  • Method for Producing Purine Nucleosides and Nucleotides by Fermentation Using Bacterium Belonging to the Genus Bacillus or Escherichia
    Publication number: 20080241888
    Abstract: Methods for producing purine nucleosides, and purine nucleotides, such as inosine and 5?-inosinic acid are provided which include using a bacterium belonging to the genus Bacillus or to the genus Escherichia wherein the purine nucleoside productivity of said bacterium is enhanced by increasing an activity of the YdhL protein. Also disclosed is the amino acid sequence of the YdhL protein from Bacillus amyloliquefaciens and the gene encoding it.
    Type: Application
    Filed: September 29, 2006
    Publication date: October 2, 2008
    Inventors: Natalia Pavlovna Zakataeva, Vitaly Arkadievich Livshits, Sergey Viktorovich Gronsky, Ekaterina Aleksandrovna Kutukova, Anna Evgenievna Novikova, Yury Ivanovich Kozlov
  • Method for producing an L-amino acid in an bacterium via altering expression levels of target proteins
    Patent number: 7399617
    Abstract: A bacterium belonging to the genus Escherichia which has an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing expression of an L-amino acid excretion protein is described. A method for producing the L-amino acid using the bacterium is also described.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: July 15, 2008
    Assignee: Ajinomoto Co., Inc.
    Inventors: Vitaliy Arkadievich Livshits, Natalia Pavlovna Zakataeva, Kazuo Nakanishi, Vladimir Veniaminovich Aleshin, Petr Vladimirovich Troshin, Irina Lyvovna Tokhmakova
  • Eschericha bacteria overexpressing the yahn gene for feedback-insensitive amino acid production
    Patent number: 6979560
    Abstract: A bacterium belonging to the genus Escherichia and having an ability to produce an L-amino acid, wherein the ability to produce the L-amino acid is increased by increasing an expression amount of an L-amino acid excretion protein, and a method for producing the L-amino acid using the bacterium.
    Type: Grant
    Filed: December 13, 1999
    Date of Patent: December 27, 2005
    Assignee: Ajinomoto Co., Inc.
    Inventors: Vitaliy Arkadievich Livshits, Natalia Pavlovna Zakataeva, Kazuo Nakanishi, Vladimir Veniaminovich Aleshin, Petr Vladimirovich Troshin, Irina Lyvovna Tokhmakova
  • Method for producing xanthosine-5'-monophosphate by fermentation using mutant strains of Coryneform bacteria
    Publication number: 20020098552
    Abstract: Xanthosine-5′-monophosphate is produced by cultivating the bacterium which has a resistance to growth inhibition by an inhibitor selected from the group consisting of inhibitors of cell membrane biosynthesis and/or functioning, phosphorylation inhibitors, uncoupling agents, RNA-polymerase inhibitors and methionine analogs, and has an ability to produce xanthosine-5′-monophosphate according to produce and accumulate xanthosine-5′-monophosphate in the culture, and recovering the xanthosine-5′-monophosphate therefrom.
    Type: Application
    Filed: November 19, 2001
    Publication date: July 25, 2002
    Applicant: AJINOMOTO CO., INC.
    Inventors: Vitaliy Arkadyevich Livshits, Lyudmila Anatolievna Kazarinova, Sergey Viktorovich Gronskiy, Ekaterina Aleksandrovna Kutukova, Natalia Pavlovna Zakataeva