Patents by Inventor Natalie V. Ostrerova

Natalie V. Ostrerova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5756702
    Abstract: Thermophilic Strand Displacement Amplification (tSDA) for amplification of nucleic acid target sequences in situ in cells in suspension, on slides or in tissues is described. Excellent specimen morphology is preserved, and either DNA targets, RNA targets, or both may be selectively amplified. In situ amplification by tSDA is compatible with immunochemical techniques, so that both amplification of target sequences and immunological staining can be perfonned on the same specimen.
    Type: Grant
    Filed: January 10, 1997
    Date of Patent: May 26, 1998
    Assignee: Becton, Dickinson and Company
    Inventors: Kenton L. Lohman, Natalie V. Ostrerova, Mark Van Cleve, Robert Alan Reid
  • Patent number: 5733752
    Abstract: Thermophilic Strand Displacement Amplification (tSDA) for amplification of nucleic acid target sequences in situ in cells in suspension, on slides or in tissues is described. Excellent specimen morphology is preserved, and either DNA targets, RNA targets, or both may be selectively amplified. In situ amplification by tSDA is compatible with immunochemical techniques, so that both amplification of target sequences and immunological staining can be performed on the same specimen.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: March 31, 1998
    Assignee: Becton, Dickinson and Company
    Inventors: Kenton L. Lohman, Natalie V. Ostrerova, Mark Van Cleve, Robert Alan Reid
  • Patent number: 5631147
    Abstract: Thermophilic Strand Displacement Amplification (tSDA) for amplification of nucleic acid target sequences in situ in cells in suspension, on slides or in tissues is described. Excellent specimen morphology is preserved, and either DNA targets, RNA targets, or both may be selectively amplified. In situ amplification by tSDA is compatible with immunochemical techniques, so that both amplification of target sequences and immunological staining can be performed on the same specimen.
    Type: Grant
    Filed: September 21, 1995
    Date of Patent: May 20, 1997
    Assignee: Becton, Dickinson and Company
    Inventors: Kenton L. Lohman, Natalie V. Ostrerova, Mark V. Cleve, Robert A. Reid