Patents by Inventor Natalja V. Kaverina

Natalja V. Kaverina has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5264432
    Abstract: 5-(w-Aminoacyl)-5,10-dihydro-11H-dibenzo(b,e)(1,4)-diazepine-11-ones, and their preparation are disclosed for treatment of antiarrhythmia and as an anticholinergic drug.
    Type: Grant
    Filed: November 4, 1992
    Date of Patent: November 23, 1993
    Assignee: Arzneimittelwerk Dresden G.m.b.H
    Inventors: Carla Ruger, Wolfgang Sauer, Dieter Lohmann, Hildegard Poppe, Reni Bartsch, Arkadij M. Lichoserstov, Natalja V. Kaverina, Alexandr P. Skoldinov, Yekaterina K. Grigoryeva, Yekaterina A. Talmachova, Valentin V. Lyskovzev, Alwina W. Stawrowskaya, Gennadi G. Chichkanov
  • Patent number: 5192760
    Abstract: New 3-carbalkoxyamino-5-(alpha-aminopropionyl)-5H-dibenz[b,f]azepines of formula I and their pharmaceutically acceptable salts were found to be suitable actives for the treatment of cardiac arrhythmia. Previously unknown 3-carbalkoxyamino-5-(alpha-halogenpropionyl)-5H-dibenz[b,f]azepines are obtained from 3-carbalkoxyamino-5H-dibenz[b,f]azepines by reaction with alpha-halogenpropionyl halides. Through their reaction with ammonia, primary amines or secondary amines, the new 3-carbalkoxyamino-5-(alpha-aminopropionyl)-5H-dibenz[b,f]azepines are obtained, which can be optionally converted into their pharmaceutically acceptable acid addition salts.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: March 9, 1993
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Helmut Wunderlich, Andreas Stark, Dieter Lohmann, Lothar Zenkar, Reni Bartsch, Hildegard Poppe, Aleksandr P. Skoldinov, Natalja V. Kaverina, Anna N. Grizenko, Valentin V. Lyskovzev, Ekaterina K. Grigoreva
  • Patent number: 5116974
    Abstract: New 3-carbalkoxyamino-5-aminoacyl-5H-dibenz[b,f]azepines and their pharmaceutically acceptable acid addition salts, and methods for their synthesis are described. These compounds are useful as antiarrhythmic agents in the treatment of heart disorders. The new compounds are made by reacting a 3-carbalkoxyamino-5-halogenacyl-5H-dibenz[b,f]azepines with an amine to form the desired target product, which can be optionally converted into its pharmaceutically acceptable acid addition salt.
    Type: Grant
    Filed: June 29, 1990
    Date of Patent: May 26, 1992
    Assignee: Arzneimittelwerk Dresden GmbH
    Inventors: Helmut Wunderlich, Andreas Stark, Lothar Zenker, Dieter Lohmann, Hildegard Poppe, Reni Bartsch, Aleksandr P. Skoldinov, Natalja V. Kaverina, Anna N. Grizenko, Valentin V. Lyskovzev