Patents by Inventor Nataly Tarasenko

Nataly Tarasenko has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NUCLEOSIDE ANALOGS AND USES THEREOF
    Publication number: 20160228444
    Abstract: Disclosed herein is a compound having general Formula I: wherein X, R1 and R2 are as defined herein, for use in methods of treating an inflammatory disease or disorder, treating or preventing anthracycline-induced cardiomyopathy, downregulating interleukin-6, MCP-1, TNF-?, and/or TLR4, and/or upregulating interleukin-10.
    Type: Application
    Filed: January 21, 2016
    Publication date: August 11, 2016
    Inventors: Ada Rephaeli, Nataly Tarasenko, Abraham Nudelman
  • 5-AMINOLEVULINIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF
    Publication number: 20150216830
    Abstract: There are provided conjugates comprising 5-aminolevulinic acid (5-ALA), an aldehyde and a carboxylic acid (e.g., a histone deacetylase inhibitor), compositions comprising same, methods for their preparation and uses thereof for treatment of cancer and anemia, and for inducing erythropoiesis.
    Type: Application
    Filed: March 20, 2015
    Publication date: August 6, 2015
    Inventors: Ada REPHAELI, Nataly TARASENKO, Zvi MALIK, Abraham NUDELMAN, Gili BERKOVITCH-LURIA, Dvir DORON
  • 5-aminolevulinic acid derivatives, methods for their preparation and uses thereof
    Patent number: 9018257
    Abstract: The present invention provides drug conjugates comprising 5-aminolevulinic acid (ALA), an aldehyde and a carboxylic acid that may function as a histone deacetylase inhibitor (HDACI). These conjugates may serve as co-drugs which release a plurality of active species in vivo. The novel drug conjugates may be used, for the treatment or prevention of cancer in PDT-dependent and/or PDT-independent (nonPDT) treatments, as well as for cosmetic uses. In addition the present invention provides novel uses for both the novel and known compounds. According to some embodiments, the present invention provides drug conjugates (co-drugs) comprising (i) ALA, (ii) an aldehyde and (iii) a carboxylic acid that may function as a histone deacetylase inhibitor (HDACO for the treatment of anemia and/or for the induction of erythropoiesis.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: April 28, 2015
    Assignees: Bar Ilan University, Ramot at Tel Aviv University Ltd.
    Inventors: Ada Rephaeli, Nataly Tarasenko, Zvi Malik, Abraham Nudelman, Gili Berkovitch-Luria, Dvir Doron
  • 5-AMINOLEVULINIC ACID DERIVATIVES, METHODS FOR THEIR PREPARATION AND USES THEREOF
    Publication number: 20140024710
    Abstract: The present invention provides drug conjugates comprising 5-aminolevulinic acid (ALA), an aldehyde and a carboxylic acid that may function as a histone deacetylase inhibitor (HDACI). These conjugates may serve as co-drugs which release a plurality of active species in vivo. The novel drug conjugates may be used, for the treatment or prevention of cancer in PDT-dependent and/or PDT-independent (nonPDT) treatments, as well as for cosmetic uses. In addition the present invention provides novel uses for both the novel and known compounds. According to some embodiments, the present invention provides drug conjugates (co-drugs) comprising (i) ALA, (ii) an aldehyde and (iii) a carboxylic acid that may function as a histone deacetylase inhibitor (HDACO for the treatment of anemia and/or for the induction of erythropoiesis.
    Type: Application
    Filed: March 22, 2012
    Publication date: January 23, 2014
    Applicants: RAMOT AT TEL AVIV UNIVERSITY LTD., BAR ILAN UNIVERSITY
    Inventors: Ada Rephaeli, Nataly Tarasenko, Zvi Malik, Abraham Nudelman, Gili Berkovitch-Luria, Dvir Doron