Patents by Inventor Natasa Hafner-Milac

Natasa Hafner-Milac has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystalline form of omeprazole
    Publication number: 20040122056
    Abstract: A novel crystalline form of the substrate known under the chemical name 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfiny] -1H-benzimidazole, and having the generic name omeprazole, hereinafter referred to as omeprozole form C, is disclosed. Further, a process for the preparation of omeprazole form C, a pharmaceutical formulation containing omeprazole form C in admixture with pharmaceutically acceptable excipients and the use of omeprazole form C for treatment of gastrointestinal disorders are disclosed.
    Type: Application
    Filed: October 17, 2003
    Publication date: June 24, 2004
    Inventors: Natasa Hafner Milac, Anton Copar, Barbara Podobnik, Andreja Cizerle Belcic, Alenka Kosak, Brina Ornik, Uros Urleb
  • Process of synthesis of 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl] sulfinyl-1 H-benzimidazole
    Publication number: 20020007069
    Abstract: An improved process of synthesis of 5-methoxy-2-[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]sulfinyl-1H-benzimidazole (omeprazole) by oxidation of 5-methoxy-2[[(4-methoxy-3,5-dimethyl-2-pyridyl)methyl]thio]benzimidazole with 3-chloroperoxybenzoic acid in ethyl acetate wherein omeprazole is poorly soluble, at a temperature between −10° C. and 5° C. is disclosed. The second step is a purification of the crude product by dissolution and reprecipitation of the final product.
    Type: Application
    Filed: July 30, 2001
    Publication date: January 17, 2002
    Inventors: Natasa Hafner Milac, Darja Jereb
  • Sodium alumoglucoheptonate, a process for its preparation and its use as sequestering agent
    Patent number: 4354940
    Abstract: Sodium alumoglucoheptonate, process of preparing from sodium glucoheptonate and sodium aluminate, and use of sodium alumoglucoheptonate as a sequestering agent.
    Type: Grant
    Filed: July 9, 1981
    Date of Patent: October 19, 1982
    Assignee: LEK, tovarna farmacevtskih in kemicnih izdelkov, n.sol.o.
    Inventors: Peter Suhac, Natasa Hafner-Milac, Bozidar Dolenc
  • Process for preparing 4-(n-hexadecylamino)-benzoic acid
    Patent number: 4304929
    Abstract: Preparation of 4-(n-hexadecylamino)-benzoic acid or salt thereof employing as catalyst quaternary ammonium or phosphonium salt.
    Type: Grant
    Filed: March 7, 1980
    Date of Patent: December 8, 1981
    Assignee: LEK tovarna farmacevtskih in kemicnih izdelkov, n.sol.o.
    Inventors: Branko Jenko, Natasa Hafner-Milac, Joza Habjan, Anton Prosen, Igor Langof
  • Sodium alumoglucoheptonate and a process for its preparation
    Patent number: 4297293
    Abstract: Sodium alumoglucoheptonate, process of preparing from sodium glucoheptonate and sodium aluminate, and use of sodium alumoglucoheptonate as a sequestering agent.
    Type: Grant
    Filed: February 6, 1980
    Date of Patent: October 27, 1981
    Assignee: LEK, tovarna farmacevtskih in kemicnih izdelkov. n.sol.o.
    Inventors: Peter Suhac, Natasa Hafner-Milac, Bozidar Dolenc