Patents by Inventor Natasha CRAKE

Natasha CRAKE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted coumarin dyes and uses as fluorescent labels
    Patent number: 12351871
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Grant
    Filed: April 9, 2024
    Date of Patent: July 8, 2025
    Assignee: ILLUMINA CAMBRIDGE LIMITED
    Inventors: Nikolai Nikolaevich Romanov, Michael Callingham, Carole Anastasi, Patrick McCauley, Niall Hynes, Natasha Crake, Xiaolin Wu, Xiaohai Liu
  • NUCLEOTIDES WITH ENZYMATICALLY CLEAVABLE 3'-O-GLYCOSIDE BLOCKING GROUPS FOR SEQUENCING
    Publication number: 20250215493
    Abstract: Embodiments of the present disclosure relate to nucleotide and nucleoside molecules with 3?-O-glycoside blocking groups. Also provided herein are methods to prepare such nucleotide and nucleoside molecules, and methods and kits for sequencing applications.
    Type: Application
    Filed: December 20, 2024
    Publication date: July 3, 2025
    Inventors: Stephane Emond, Antoine Francais, Adam Culley, Cassie Zerbe, Natasha Crake, Elena Cressina, Alexandre Hofer
  • SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS
    Publication number: 20240271209
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: April 9, 2024
    Publication date: August 15, 2024
    Inventors: Nikolai Nikolaevich Romanov, Michael Callingham, Carole Anastasi, Patrick McCauley, Niall Hynes, Natasha Crake, Xiaolin Wu, Xiaohai Liu
  • Substituted coumarin dyes and uses as fluorescent labels
    Patent number: 11981964
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Grant
    Filed: July 26, 2021
    Date of Patent: May 14, 2024
    Assignee: Illumina Cambridge Limited
    Inventors: Nikolai Nikolaevich Romanov, Michael Callingham, Carole Anastasi, Patrick Mccauley, Niall Hynes, Natasha Crake, Xiaolin Wu, Xiaohai Liu
  • SUBSTITUTED COUMARIN DYES AND USES AS FLUORESCENT LABELS
    Publication number: 20220033900
    Abstract: The present application relates to substituted coumarin derivatives and their uses as fluorescent labels. These compounds may be used as fluorescent labels for nucleotides in nucleic acid sequencing applications.
    Type: Application
    Filed: July 26, 2021
    Publication date: February 3, 2022
    Inventors: Nikolai Nikolaevich ROMANOV, Michael CALLINGHAM, Carole ANASTASI, Patrick MCCAULEY, Niall HYNES, Natasha CRAKE, Xiaolin WU, Xiaohai LIU