Patents by Inventor Natasha Vinanica

Natasha Vinanica has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Blockade of CD7 expression and chimeric antigen receptors for immunotherapy of T-cell malignancies
    Patent number: 11945865
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Grant
    Filed: July 14, 2022
    Date of Patent: April 2, 2024
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana
  • BLOCKADE OF CD7 EXPRESSION AND CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY OF T-CELL MALIGNANCIES
    Publication number: 20220348655
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Application
    Filed: July 14, 2022
    Publication date: November 3, 2022
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana
  • Blockade of CD7 expression and chimeric antigen receptors for immunotherapy of T-cell malignancies
    Patent number: 11440958
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: September 13, 2022
    Assignee: NATIONAL UNIVERSITY OF SINGAPORE
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana
  • A Method to Specifically Stimulate Survival and Expansion of Genetically-Modified Immune Cells
    Publication number: 20210324388
    Abstract: The present invention relates to a vector encoding a wildtype or truncated form of erythropoietin receptor (EpoR) to promote T cell survival and proliferation. Specifically, it exemplifies a bicistronic vector that expresses a truncated EpoR with an anti-CD19-41 BB-003? chimeric antigen receptor (CAR) that has a greater ex vivo expansion than CAR-T cells and demonstrates a significantly higher anti-leukemic activity in vivo. It also describes the method of producing cells expressing said vector and the use of these cells to kill CD19+ tumour cells.
    Type: Application
    Filed: August 27, 2019
    Publication date: October 21, 2021
    Inventors: Natasha Vinanica, Arthur Yong, Dario Campana, Masaru Imamura
  • Blockade of CD7 expression and chimeric antigen receptors for immunotherapy of T-cell malignancies
    Patent number: 10550183
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Grant
    Filed: November 22, 2017
    Date of Patent: February 4, 2020
    Assignee: National University of Singapore
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana
  • BLOCKADE OF CD7 EXPRESSION AND CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY OF T-CELL MALIGNANCIES
    Publication number: 20180179280
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Application
    Filed: November 22, 2017
    Publication date: June 28, 2018
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana
  • BLOCKADE OF CD7 EXPRESSION AND CHIMERIC ANTIGEN RECEPTORS FOR IMMUNOTHERAPY OF T-CELL MALIGNANCIES
    Publication number: 20180148506
    Abstract: The present invention provides compositions comprising an anti-CD7 chimeric activating receptor (CAR) and an anti-CD7 protein expression blocker, and methods of using such compositions in cancer therapy.
    Type: Application
    Filed: November 22, 2017
    Publication date: May 31, 2018
    Inventors: Yi Tian Png, Natasha Vinanica, Takahiro Kamiya, Dario Campana