Patents by Inventor Nathalie Bamas-Jacques

Nathalie Bamas-Jacques has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7604970
    Abstract: The present invention relates to novel variants of the PapM polypeptide of bacteria of the Streptomyces genus which possess a substrate selectivity and/or an improved effectiveness compared to the wild-type polypeptide. It also relates to the nucleic acids encoding these variants, to the microorganisms which incorporate these nucleic acids and to their use for producing B components of Streptogramins.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: October 20, 2009
    Assignee: Aventis Pharma S.A.
    Inventors: Nathalie Bamas-Jacques, Denis Thibaut, Alain Famechon
  • Publication number: 20080188378
    Abstract: The present invention relates to novel variants of the PapM polypeptide of bacteria of the Streptomyces genus which possess a substrate selectivity and/or an improved effectiveness compared to the wild-type polypeptide. It also relates to the nucleic acids encoding these variants, to the microorganisms which incorporate these nucleic acids and to their use for producing B components of Streptogramins.
    Type: Application
    Filed: June 25, 2003
    Publication date: August 7, 2008
    Applicant: Aventis Pharma S.A.
    Inventors: Nathalie Bamas-Jacques, Denis Thibaut, Alain Famechon
  • Patent number: 6833382
    Abstract: Novel group B streptogramin-like compounds of general formula (I), and a method for preparing streptogramines by mutasynthesis using a mutated micro-organism to influence the biosynthesis of at least one of the precursors of group B streptogramins are disclosed. Novel nucleotide sequences involved in the biosynthesis of said precursors, and their uses, are also disclosed.
    Type: Grant
    Filed: November 15, 2001
    Date of Patent: December 21, 2004
    Assignee: Aventis Pharma S.A.
    Inventors: Véronique Blanc, Denis Thibaut, Nathalie Bamas-Jacques, Francis Blanche, Joël Crouzet, Jean-Claude Barriere, Laurent Debussche, Alain Famechon, Jean-Marc Paris, Gilles Dutruc-Rosset
  • Publication number: 20020142947
    Abstract: Novel group B streptogramine-like compounds of general formula (I), and a method for preparing streptogramines by muta-synthesis using a mutated micro-organism to influence the biosynthesis of at least one of the precursors of group B streptogramines, are disclosed. Novel nucleotide sequences involved in the biosynthesis of said precursors, and their uses, are also disclosed.
    Type: Application
    Filed: November 15, 2001
    Publication date: October 3, 2002
    Applicant: Aventis Pharma, S.A.
    Inventors: Veronique Blanc, Denis Thibaut, Nathalie Bamas-Jacques, Francis Blanche, Joel Crouzet, Jean-Claude Barriere, Laurent Debussche, Alain Famechon, Jean-Marc Paris, Gilles Dutruc-Rosset
  • Patent number: 6352839
    Abstract: The invention provides a method for preparing streptogramins using genetically-modified microorganisms to influence the biosynthesis of at least one of the precursors of the group B streptogramins. Cultures of the genetically-modified microorganisms are supplemented with a least one precursor that is different from the streptogramin precursor whose biosynthesis is altered and the streptogramins produced are recovered.
    Type: Grant
    Filed: March 20, 1997
    Date of Patent: March 5, 2002
    Assignee: Aventis Pharma S.A.
    Inventors: Véronique Blanc, Denis Thibaut, Nathalie Bamas-Jacques, Francis Blanche, Joël Crouzet, Jean-Claude Barriere, Laurent Debussche, Alain Famechon, Jean-Marc Paris, Gilles Dutruc-Rosset