Patents by Inventor Nathalie Juge

Nathalie Juge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SIALIC ACID TRANSPORTER PROTEINS AS BIOMARKERS AND DRUG TARGETS
    Publication number: 20210254138
    Abstract: A method of identifying, monitoring and/or diagnosing mucosal bacterial presence or infection, said method including the step of detecting at least part of a sialic acid transporter protein encoded by Ruminococcus gnavus (R. gnavus) ATCC 29149 Nan cluster. In addition, a method of inhibition of the growth of bacterium, said method including the step of inhibition of a sialic acid transporter protein is included.
    Type: Application
    Filed: June 17, 2019
    Publication date: August 19, 2021
    Applicant: Quadram Institute Bioscience
    Inventors: Nathalie Juge, Andrew Bell, John Walshaw
  • Intramolecular Trans-Sialidase
    Publication number: 20190037899
    Abstract: The present invention relates to an intramolecular trans-sialidase (IT-sialidase) enzyme from Ruminococcus gnavus and fragments thereof. It also relates to methods of production of the IT-sialidase or its fragments, in addition to uses of the IT-sialidase, its fragments, or compositions comprising the IT-sialidase. One of the uses of the IT-sialidase or its fragments encompassed by the present invention is a method for production of 2,7-anhydro sialic acid derivatives. Further uses of the IT-sialidase enzyme include the therapeutic and prophylactic treatment of infections and respiratory conditions.
    Type: Application
    Filed: February 6, 2017
    Publication date: February 7, 2019
    Inventors: Nathalie Juge, Marie Maguelonne Monestier, Robert Andrew Field