Patents by Inventor Nathan Alves

Nathan Alves has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Enzyme/Protein Packaged Bacterial Vesicles for Therapeutic Delivery
    Publication number: 20160222372
    Abstract: A method of producing a protein includes providing a bacterial cell expressing both (a) a protein of interest fused to one of the SpyTag/SpyCatcher pair and (b) an outer membrane protein fused to the other of the SpyTag/SpyCatcher pair; causing the bacterial cell to express both of the protein of interest fusion and the outer membrane protein fusion in outer membrane vesicles; and purifying the outer membrane vesicles.
    Type: Application
    Filed: January 29, 2016
    Publication date: August 4, 2016
    Inventors: Scott Walper, Nathan Alves, Kendrick Turner, Igor L. Medintz, George P. Anderson
  • SELECTIVE UV CROSSLINKING OF PEPTIDES AND FUNCTIONAL MOIETIES TO IMMUNOGLOBULINS
    Publication number: 20160022834
    Abstract: The invention provides for a method of crosslinking a hetero-bifunctional photo crosslinking compound to an immunoglobulin having at least one heterocyclic photo reactive group and at least one non-photo reactive group where the non-photo reactive group is coupled to an effector molecule and the photo reactive group is coupled to the nucleotide binding site of an immunoglobulin. Alternatively, the photo crosslinker contains an orthogonal reactive group such as a thiol, which can be coupled to an effector molecule or functionalized ligand.
    Type: Application
    Filed: March 14, 2014
    Publication date: January 28, 2016
    Applicant: UNIVERSITY OF NOTRE DAME DU LAC
    Inventors: Zihni Basar Bilgicer, Nathan Alves