Abstract: Improved intraluminal imaging devices and methods of manufacturing the devices are provided. In an embodiment, an intraluminal imaging device can include a flexible elongate member configured to be positioned within a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion, an ultrasound scanner assembly coupled to and positioned distally of the distal portion of the flexible elongate member, the ultrasound scanner assembly comprising a plurality of electrical components disposed adjacent to a cavity of the ultrasound scanner assembly, and a coating extending over and directly contacting the distal portion of the flexible elongate member and a portion of the ultrasound scanner assembly to hermetically seal the cavity of the ultrasound scanner assembly. The coating provides a uniform barrier layer extending over a junction of two or more components having diverse cross-sectional profiles to prevent ingress of external fluids into the scanner assembly.

Abstract: An intraluminal ultrasound imaging device includes a flexible elongate member and an ultrasound imaging assembly coupled to a distal portion of the flexible elongate member. The ultrasound imaging assembly includes a flexible substrate comprising a scanner body portion, one or more control circuits mounted on the scanner body portion, and one or more transducer elements mounted on the scanner body portion. The ultrasound imaging assembly also includes an attachment portion extending proximally from the scanner body portion. The attachment portion defines a path that curves in a first direction and different second direction, and includes a plurality of conductive traces in electrical communication with the one or more control circuits. The plurality of conductive traces follows the curved path of the attachment portion, and each conductive trace comprises a pattern that bends relative to the curved path of the attachment portion.

Abstract: An intraluminal imaging catheter includes a flexible elongate member configured to be positioned within a body lumen of a patient. The flexible elongate member includes a proximal portion and a distal portion. The catheter includes an ultrasound imaging assembly coupled to the flexible elongate member at the distal portion. The ultrasound imaging assembly includes a flexible substrate. The flexible substrate includes a first surface and an opposite, second surface. The imaging assembly also includes an ultrasound transducer array disposed on the flexible substrate. The flexible substrate includes a first recess extending from the first surface to the second surface. The ultrasound imaging assembly is coupled to the flexible elongate member via a first adhesive positioned in a space between the flexible substrate and the flexible elongate member via the first recess.

Abstract: An intraluminal imaging device includes a flexible elongate member configured to be positioned within a body lumen of a patient. An ultrasound imaging assembly is disposed at the distal portion of the flexible elongate member. In some embodiments, a tip member with a protrusion is coupled to the ultrasound imaging assembly. The ultrasound imaging assembly and/or the flexible elongate member includes a recess that that receives the protrusion. In some embodiments, a support member includes a first stand, a second stand, a third stand, and a ridge. A flexible substrate with integrated circuit chips and an ultrasound transducer assembly is positioned around the support member. A filling material and an acoustic backing material are disposed in different spaces defined by the stands and flexible substrate. A tip member includes a groove receiving the ridge.

Abstract: An intravascular imaging probe including a multiple material support member or chassis, and associated devices, systems, and methods are provided. According to one embodiment, an intraluminal ultrasound imaging catheter includes a flexible elongate member configured to be positioned within a body lumen of a patient, a support member coupled to a distal portion of the flexible elongate member, and an ultrasound scanner assembly positioned around the support member. The support member includes a hollow inner member comprising a first material, and a first annular member positioned around a perimeter of the hollow inner member at a proximal portion of the hollow inner member. The first annular member extends radially outward from the hollow inner member and includes a second material that is different from the first material.

Abstract: An imaging catheter assembly is provided. In one embodiment, the imaging catheter assembly includes a flexible elongate member comprising a distal portion and a proximal portion; a tip member coupled to a distal end of the distal portion of the flexible elongate member, wherein the tip member includes a tubular body comprising a closed distal end, an opened proximal end, and a proximal curved top outer wall extending from the proximal opened end and tapering into a distal flat top outer wall towards the closed distal end; and an imaging component mounted within the tip member. In one embodiment, the imaging catheter assembly includes a flexible elongate member; a tip member coupled to a distal end of the flexible elongate member, wherein the tip member includes a cylindrical body and a uniform outer diameter; and an imaging component mounted within the tip member.

Abstract: An intraluminal device is provided. In on embodiment, an intraluminal device includes a flexible elongate member including a proximal portion and a distal portion; an imaging component coupled to the distal portion of the flexible elongate member; and a plurality of radiopaque markers positioned at the distal portion of the flexible elongate member, wherein the plurality of radiopaque markers are separated from each other, wherein the plurality of radiopaque markers are arranged on the flexible elongate member at two different orientations with respect to the imaging component, and wherein at least a first radiopaque marker of the plurality of radiopaque markers includes an arc-shaped portion and an extended portion extending from the arc-shaped portion.

Abstract: In an embodiment, an intraluminal device is disclosed. One embodiment of the intraluminal device comprises a flexible elongate body comprising a distal portion configured to be positioned within a body lumen of a patient and a functional device disposed at the distal portion of the flexible elongate body, the functional device configured to obtain physiological data or perform a treatment within the body lumen. The intraluminal device further comprises a stiffening member moveably disposed within and along a longitudinal length of the flexible elongate body without extending beyond a distal end of the flexible elongate body, the stiffening member being moveable during an intraluminal procedure to selectively vary a stiffness of the intraluminal device.

Abstract: Improved intraluminal imaging devices and methods of manufacturing the devices are provided. In an embodiment, an intraluminal imaging device can include a flexible elongate member configured to be positioned within a body lumen of a patient, the flexible elongate member comprising a proximal portion and a distal portion, an ultrasound scanner assembly coupled to and positioned distally of the distal portion of the flexible elongate member, the ultrasound scanner assembly comprising a plurality of electrical components disposed adjacent to a cavity of the ultrasound scanner assembly, and a coating extending over and directly contacting the distal portion of the flexible elongate member and a portion of the ultrasound scanner assembly to hermetically seal the cavity of the ultrasound scanner assembly. The coating provides a uniform barrier layer extending over a junction of two or more components having diverse cross-sectional profiles to prevent ingress of external fluids into the scanner assembly.

Abstract: An imaging catheter assembly is provided. In one embodiment, the imaging catheter assembly includes a flexible elongate member comprising a distal portion and a proximal portion; a tip member coupled to a distal end of the distal portion of the flexible elongate member, wherein the tip member includes a tubular body comprising a closed distal end, an opened proximal end, and a proximal curved top outer wall extending from the proximal opened end and tapering into a distal flat top outer wall towards the closed distal end; and an imaging component mounted within the tip member. In one embodiment, the imaging catheter assembly includes a flexible elongate member; a tip member coupled to a distal end of the flexible elongate member, wherein the tip member includes a cylindrical body and a uniform outer diameter; and an imaging component mounted within the tip member.